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Evolutionary Diversity as a Source for Anticancer Molecules
discusses evolutionary diversity as source for anticancer agents
derived from bacteria, algae, bryophytes, pteridophytes, and
gymnosperms. The book goes over the isolation of anticancer agents
and the technologyenabled screening process used to develop
anticancer drugs. The book also includes discussion of the
nutraceuticals and natural products derived from invertebrates that
can be used as part of cancer treatment. Evolutionary Diversity as
a Source for Anticancer Molecules also deals with some of the
current challenges in the prevention of cancer as well as the side
effects of conventional drugs used for cancer patients. This book
is a valuable resource for cancer researchers, oncologists,
biotechnologists, pharmacologists, and any member of the biomedical
field interested in understanding more about natural products with
anticancer potential.
Xenobiotics in Chemical Carcinogenesis: Translational Aspects in
Toxicology covers the translational toxicology of xenobiotics
substances in carcinogenesis by explaining the toxicokinetic and
toxicodynamic, toxicogenomic, biotransformation, and resistance
mechanisms in the human body. The book begins with a historical
review and link to future prospects for chemical carcinogenesis. It
discusses major environmental xenobiotics and their risks in
inducing cancer, along with content on toxic xenobiotics and their
routes of exposure in humans, the role of xenobiotic metabolism in
carcinogenesis, and the toxicokinetic and toxicodynamic of
xenobiotics in cancer development. Lastly, the book explores
current achievements such as using toxicogenomics for predicting
the carcinogenicity of xenobiotic substances and the challenges
posed by carcinogenic xenobiotic substances when examining
preventive methods, diagnosis, and the development of anticancer
drugs for specific toxicants.
Phytochemicals and derivatives have become promising alternatives
to increase treatment potential in cancer patients with minimal
side effects. Drug-delivery Systems of Phytochemicals as
Therapeutic Strategies in Cancer Therapy elucidates the importance
of various phytochemicals in cancer therapy and explains various
routes/methods to deliver phytochemicals for overcoming the
problems associated with delivery system in cancer treatment.
Several nanotechnological methods are followed to enhance drug
solubility, sustainability, bioavailability and gastrointestinal
permeability of these phytochemicals. The advanced field of
drug-delivery systems explains that combination therapy for cancer
treatment has important benefits over mono-delivery therapeutics.
Natural compounds, because of their biobased origin, have drawn
higher attention than synthetic drugs. Synthesis of
nano-phytomedicines has impacted the bioavailability of
phytochemicals. Novel formulations have been synthesized loaded
with phytochemicals and have revealed extraordinary results in
treatment of various cancers. Current understanding of the relevant
information presented in Drug-delivery systems of phytochemicals as
therapeutic strategies in cancer therapy fulfils the requirements
of oncologists, molecular biologists, pharmacologist and related
researchers, who want to work in the areas of drug development
targeting phytochemicals for cancer therapy
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