Empirical and anecdotal data suggests that education technology increases access to learning, democratizes knowledge, and increases the breadth and richness of the learning experience. Due to this, there is a need to disseminate awareness and information about the role of emotional intelligence and technology from various dimensions to help students and teachers maintain the quality of e-learning and emotional well-being. Technology-Driven E-Learning Pedagogy Through Emotional Intelligence provides updated research perspectives focusing on the relationship between e-learning pedagogy, technology, and emotional intelligence. Covering key topics such as blended learning, resilience, social awareness, and empathy, this reference work is ideal for administrators, researchers, scholars, academicians, practitioners, instructors, and students.

This second edition volume expands on the previous edition with updated discussions on new genetic, molecular, and cellular methods used to study somatic stem cells. The chapters in this book focus on the isolation, classification, purity, and plasticity of these stem cells in a variety of organic tissues. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Somatic Stem Cells: Methods and Protocols, Second Edition is a valuable resource for both novice and experienced molecular biologists, developmental biologists, tissue engineers, and geneticists who are interested in stem cell research and its potentials in regenerative medicine.

miRNAs are a class of endogenous, small non-protein coding RNA molecules (~ 22 nucleotides) which are novel post-transcriptional regulators of gene expression. Since we have hundreds of miRNAs, the major challenge is now to understand their specific biological function. In fact the experimental evidence suggests that signaling pathways could be ideal candidates for miRNA-mediated regulation. Several studies suggest that miRNAs affect the responsiveness of cells to signaling molecules such as WNT, Notch, TGF- and EGFR. Altered expression of particular miRNAs has been implicated in the onset and development of cancer and could be used as potential biomarkers for the disease. Recently, many studies have found miRNAs have crucial regulatory roles in Cancer stem cells (CSCs) a kind of tumor initiating cells (TICs) and dormancy. Findings also suggest that DNA methylation may be important in regulating the expression of many miRNAs in several cancer initiating cells. Several miRNAs are known to either upregulated or downregulated in CSCs when compared to non-cancerous cells from the same tissues. CSCs are a small subpopulation of cells identified in a variety of tumors and involve in self-renewal, differentiation, chemoresistance and tumorigenesis. The volume will give a comprehensive account of important advancements in the area of miRNAs and cancer.

"Mouse Genetics: Methods and Protocols" provide selected mouse genetic techniques and their application in modeling varieties of human diseases. The chapters are mainly focused on the generation of different transgenic mice to accomplish" "the manipulation of genes of interest, tracing cell lineages and modeling human diseases. Composed in the highly successful "Methods in Molecular Biology "series format, each chapter contains a brief introduction, a list of necessary materials, systematic, readily reproducible methods and a notes section, which shares tips on troubleshooting in order to avoid known pitfalls.

Comprehensive and authoritative, "Mouse Genetics: Methods and Protocols" promises to deliver fundamental techniques and protocols to geneticists, molecular biologists, cell and developmental biologists, students and postdoctoral fellows working in the various disciplines of mouse biology and modeling human disease.

Stem cells are found in almost all organisms from the early stages of development to the end of life. There are several types of stem cells and all of them may prove useful for medical research; however, each of the different types has both promise and limitations. "Somatic Stem Cells: Methods and Protocols" presents selected genetic, molecular, and cellular techniques used in somatic stem cell research and its clinical application. Chapters focus on the isolation, characterization, purity, plasticity, and clinical uses of somatic stem cells from a variety of human and animal tissues. Written in the highly successful "Methods in Molecular Biology " series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Through and intuitive, "Somatic Stem Cells: Methods and Protocols" seeks to provides scientists with the fundamental techniques of stem cell research and its potential application in regenerative medicine.

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This fully updated edition provides selected mouse genetic techniques and their application in modeling varieties of human diseases. The chapters are mainly focused on the generation of different transgenic mice to accomplish the manipulation of genes of interest, tracing cell lineages, and modeling human diseases. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Mouse Genetics: Methods and Protocols, Second Edition delivers fundamental techniques and protocols to geneticists, molecular biologists, cell and developmental biologists, students, and postdoctoral fellows working in the various disciplines of genetics, developmental biology, mouse genetics, and modeling human diseases.

In this comprehensive and cutting-edge book, leading experts explore the parameters that define germline stem cells and the mechanisms that regulate the cell behavior in order to better isolate, characterize and maintain them. The volume begins by providing protocols for germline stem cell identification and regulation in model organisms, and concludes with detailed chapters covering current techniques involving in vitro culture and the applications of the cells.

Stem cells are found in almost all organisms from the early stages of development to the end of life. There are several types of stem cells and all of them may prove useful for medical research; however, each of the different types has both promise and limitations. Somatic Stem Cells: Methods and Protocols presents selected genetic, molecular, and cellular techniques used in somatic stem cell research and its clinical application. Chapters focus on the isolation, characterization, purity, plasticity, and clinical uses of somatic stem cells from a variety of human and animal tissues. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Through and intuitive, Somatic Stem Cells: Methods and Protocols seeks to provides scientists with the fundamental techniques of stem cell research and its potential application in regenerative medicine.

Mouse Genetics: Methods and Protocols provide selected mouse genetic techniques and their application in modeling varieties of human diseases. The chapters are mainly focused on the generation of different transgenic mice to accomplish the manipulation of genes of interest, tracing cell lineages and modeling human diseases. Composed in the highly successful Methods in Molecular Biology series format, each chapter contains a brief introduction, a list of necessary materials, systematic, readily reproducible methods and a notes section, which shares tips on troubleshooting in order to avoid known pitfalls. Comprehensive and authoritative, Mouse Genetics: Methods and Protocols promises to deliver fundamental techniques and protocols to geneticists, molecular biologists, cell and developmental biologists, students and postdoctoral fellows working in the various disciplines of mouse biology and modeling human disease.

In this comprehensive and cutting-edge book, leading experts explore the parameters that define germline stem cells and the mechanisms that regulate the cell behavior in order to better isolate, characterize and maintain them. The volume begins by providing protocols for germline stem cell identification and regulation in model organisms, and concludes with detailed chapters covering current techniques involving in vitro culture and the applications of the cells.

This fully updated edition provides selected mouse genetic techniques and their application in modeling varieties of human diseases. The chapters are mainly focused on the generation of different transgenic mice to accomplish the manipulation of genes of interest, tracing cell lineages, and modeling human diseases. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Mouse Genetics: Methods and Protocols, Second Edition delivers fundamental techniques and protocols to geneticists, molecular biologists, cell and developmental biologists, students, and postdoctoral fellows working in the various disciplines of genetics, developmental biology, mouse genetics, and modeling human diseases.

Empirical and anecdotal data suggests that education technology increases access to learning, democratizes knowledge, and increases the breadth and richness of the learning experience. Due to this, there is a need to disseminate awareness and information about the role of emotional intelligence and technology from various dimensions to help students and teachers maintain the quality of e-learning and emotional well-being. Technology-Driven E-Learning Pedagogy Through Emotional Intelligence provides updated research perspectives focusing on the relationship between e-learning pedagogy, technology, and emotional intelligence. Covering key topics such as blended learning, resilience, social awareness, and empathy, this reference work is ideal for administrators, researchers, scholars, academicians, practitioners, instructors, and students.

miRNAs are a class of endogenous, small non-protein coding RNA molecules (~ 22 nucleotides) which are novel post-transcriptional regulators of gene expression. Since we have hundreds of miRNAs, the major challenge is now to understand their specific biological function. In fact the experimental evidence suggests that signaling pathways could be ideal candidates for miRNA-mediated regulation. Several studies suggest that miRNAs affect the responsiveness of cells to signaling molecules such as WNT, Notch, TGF- and EGFR. Altered expression of particular miRNAs has been implicated in the onset and development of cancer and could be used as potential biomarkers for the disease. Recently, many studies have found miRNAs have crucial regulatory roles in Cancer stem cells (CSCs) a kind of tumor initiating cells (TICs) and dormancy. Findings also suggest that DNA methylation may be important in regulating the expression of many miRNAs in several cancer initiating cells. Several miRNAs are known to either upregulated or downregulated in CSCs when compared to non-cancerous cells from the same tissues. CSCs are a small subpopulation of cells identified in a variety of tumors and involve in self-renewal, differentiation, chemoresistance and tumorigenesis. The volume will give a comprehensive account of important advancements in the area of miRNAs and cancer.

In this study, Synthetic Hexaploid lines of Wheat viz., Syn 4, Syn 55 and Syn 86 were screened for resistance against virulence stem rust pathotype 40A at Division of Genetics, IARI, New Delhi. The nature of inheritance of gene governing the resistance in these synthetic lines and their allelic relationship were studied. The gene for resistance in Syn 4 and Syn 55 was found to be same, as confirmed by the test of allelism. In Syn 86. The resistance to stem rust was governed by two genes one dominant and one recessive). The F2 population developed from a cross between Syn 4 x Agra local, was used to identify molecular marker linked to stem rust resistance gene. A total of 75 RAPD's and 35 SSR primer pair were selected covering D-Genome and B-Genome on the basis of chromosomal location of resistance gene. The SSR marker Xgwm533 was found to be linked with resistance gene at a distance of 5cM and marker Xgwm389 was co-segregating. Xgwm533 was taken from B-Genome hence, the resistance gene to be located on 3-B Genome of wheat. The use of these markers in combination with other marker could better predict the presence of gene for resistance to stem rust in breeding population.

The book is prepared for small, medium and large categories of farmers to study the gap between existing and balanced feeding schedule, feed-milk production relationship and least cost feeding schedule for milch cattle & buffaloes in Hisar and Karnal districts of Haryana state in India. The book concludes, the highest quantity of green fodder and concentrate were offered on large farms. While on small farms feeding of dry fodder was higher in both districts. Milk yield per milch animal was found higher on larger farms than smaller ones in both the districts. The optimum least cost feeding schedule for milch dairy animals was found profitable over existing feeding schedule in both districts. Thus farmers could reduce their feeding cost and maximize profit from dairy enterprise by the adoption of least cost feeding schedule and better management of their milch dairy animals. In case of feed-milk production relationship digestible crude protein (DCP), concentrate and green fodder were observed to have significant impact on milk yield in both districts.

Dr. Ram Singh is currently Associate Professor, School of Social Sciences, College of Post Graduate Studies, Central Agricultural University, Barapani, Meghalaya, India. He has a wide research experience and worked in different national and international institute of repute viz, NDRI, Karnal, Haryana, India, CSSRI, Karnal, Haryana, India, CCS HAU, Hisar, Haryana, India and International Maize and Wheat Improvement Center (CIMMYT).He is guiding and teaching post graduate students.His main fields of interest are Agricultural Economics, Natural Resource Economics and Agricultural Marketing. He has authored 29 research papers, 4 popular articles, 12 abstract papers which have been published in various national and international journals and 1 book chapter, 3 project report and 1 research bulletin.He has been participated and presented many research papers and posters in various national and international seminars, workshops, symposium and conferences. He visited Philippines, Bangladesh, Pakistan and Nepal and conducted trainings for various research projects. Presently he is Member Executive Committee in Indian Society of Agricultural Marketing, Nagpur

The book reports how the livelihoods of people particularly in rural area of Nepal depends on natural resources. The study shows the contribution of watershed management; which is management of complex elements(Water, Land, Forest, and People itself) to sustain their livelihoods. The farming system heavily depends on natural resources. Increase in population and its dependency on land resources has resulted on the degradation of watersheds. Government of Nepal has been implementing various watershed management programs to address the issues. Poverty reduction is worthless without considering the sustainable management of land resources, as the majority of the people depend on these resources. Peoples' participation is must for sustainable watershed management. Author has explored different aspects of watershed management and tried to find out the contribution of watershed management program to the livelihoods of local people considering sustainable livelihood framework by identifying the criteria and indicators of watershed management activities. The work is quite beneficial to researchers, students, practitioners and policy makers involved in NRM.

Although there have been tremendous progress in cancer research and treatment, the mortality caused by this disease is still very high. Cancer is the leading cause of death worldwide and second leading cause of death in the United States of America. The book covers topics including the role of various signalling pathway in development, regulation of cell fate, tumour angiogenesis, duodenal neoplasias, breast, colorectal and prostate cancer, cancer development and progression, microRNA in cancer and epigenetic regulation of cancer. This book will provide valuable information for cell biologists, geneticists, cancer biologists, clinicians, and students involved in various aspects of cell signalling, regulation of genes and cancer.