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The field of statistics not only affects all areas of scientific activity, but also many other matters such aspublic policy. It is branching rapidly into so many different subjects that a series of handbooks is the only way of comprehensively presenting the various aspects of statistical methodology, applications, and recent developments. The Handbook of Statistics, a series of self-contained reference
books. Each volume is devoted to a particular topic in statistics
with Volume 28 dealing with bioinformatics. Every chapter is
written by prominent workers in the area to which the volume is
devoted. The series is addressed to the entire community of
statisticians and scientists in various disciplines who use
statistical methodology in their work. At the same time, special
emphasis is placed on applications-oriented techniques, with the
applied statistician in mind as the primary audience.
One of the major themes of human population genetics is assaying genetic variation in human populations. The ultimate goal of this objective is to understand the extent of genetic diversity and the use of this knowledge to reconstruct our evolutionary history. The discipline had undergone a revolutionary transition with the advent of molecular techniques in the 1980s. With this shift, statistical methods have also been developed to perceive the biological and molecular basis of human genetic variation. Using the new perspectives gained during the above transition, this volume describes the applications of molecular markers spanning the autosomal, Y-chromosomal and mitochondrial genome in the analysis of human diversity in contemporary populations. This is the first reference book of its kind to bring together data from these diverse sets of markers for understanding evolutionary histories and relationships of modern humans in a single volume.
One of the major themes of human population genetics is assaying genetic variation in human populations. The ultimate goal of this objective is to understand the extent of genetic diversity and the use of this knowledge to reconstruct our evolutionary history. The discipline had undergone a revolutionary transition with the advent of molecular techniques in the 1980s. With this shift, statistical methods have also been developed to perceive the biological and molecular basis of human genetic variation. Using the new perspectives gained during the above transition, this volume describes the applications of molecular markers spanning the autosomal, Y-chromosomal and mitochondrial genome in the analysis of human diversity in contemporary populations. This is the first reference book of its kind to bring together data from these diverse sets of markers for understanding evolutionary histories and relationships of modern humans in a single volume.
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