Leather is an important economic commodity. The feel of the leather invariably decides the quality of the leather. The rate and mode of drying alters the physico-mechanical properties of the leather significantly. Typically, in leather manufacture wet leathers with about 70% moisture levels are subjected to mechanical squeezing operation, samming, for removal of freely held water before subjecting to conventional drying processes to produce leathers with 15- 20% moisture. Experiments are conducted to gain a clear picture of how drying variable affects the mechanical properties of dried leathers. Shorter drying time and proper initial water content are favorable conditions to produce stronger and softer leather. Possibility have been explored of using mass quantity such as drying rate to generalize relationship between drying variables and mechanical properties. From the experiments, it can be concluded that by vacuum drying process stronger and softer leather can be achieved, which will have high tensile strength, grain crack strength and tongue tear strength. Further they would not undergo any wear and tear during finishing processes.