Longitudinal data consists of a series of repeated observations of the same subjects over an extended time frame, and is thus useful for measuring change. Such studies arise in a variety of fields, such as health sciences, genomic studies, experimental physics, sociology, sports and student enrollment in universities. Many challenges can arise in longitudinal studies. For example, in health studies, intra-subject correlation of responses must be accounted for, covariates can vary with time, and bias can arise due to patients dropping out of the study. This volume under development brings recent and classical works in the modeling and analysis of longitudinal data and their utility for improving society.

Environmental and Health Management of Novel Coronavirus Disease (COVID-19) examines mitigation measures that can be adopted at the time of a novel coronavirus outbreak to lessen environmental contamination and impacts on human health. The book discusses origin, structure and pathogenesis, epidemiology, environmental transmission and the potential spread routes of COVID-19 via surfaces, air, water, wastewater, medical waste and food products. It also covers guidelines and protocols for setting safety conditions to provide adequate health care and reduce the risk of infection in health and non-healthcare settings, along with preventative measures and disinfection technologies. In addition, the book discusses challenges, opportunities and future perspectives, the global crisis, and global consequences on the environment and health. With contributions from experts, this book presents a multidisciplinary reference resource for virologists, microbiologists, public health professionals, environmental health managers and others engaged in the study and mitigation of the environmental and health impacts of the virus.

Integrated Population Biology and Modeling: Part A offers very complex and precise realities of quantifying modern and traditional methods of understanding populations and population dynamics. Chapters cover emerging topics of note, including Longevity dynamics, Modeling human-environment interactions, Survival Probabilities from 5-Year Cumulative Life Table Survival Ratios (Tx+5/Tx): Some Innovative Methodological Investigations, Cell migration Models, Evolutionary Dynamics of Cancer Cells, an Integrated approach for modeling of coastal lagoons: A case for Chilka Lake, India, Population and metapopulation dynamics, Mortality analysis: measures and models, Stationary Population Models, Are there biological and social limits to human longevity?, Probability models in biology, Stochastic Models in Population Biology, and more.

Environmental pollution by man-made Persistent Organic Chemicals (POCs) has been a serious global issue for over half a century. Exposure to POCs may result in health effects, including, endocrine disruption leading to birth defects, intellectual disability, low testosterone, childhood obesity, autism and attention deficit hyperactivity disorder (ADHD). Therefore, POCs have been the subject of intensive regional, national, and international efforts to limit the production, use, and disposal of these chemicals. Since POCs are ubiquitous and recalcitrant, and cause long-term effects on wildlife and humans, trend monitoring studies are valuable in making clear the behavior and fate of these compounds and to protect our environment and living resources. The Pacific Basin is a unique geographical region representing tropical, temperate and polar zones. This region is home to two-thirds of the world's population and consists of rapidly growing economies (countries) and highly developed countries. Due to this diversity of climatic and socio-economic conditions, environment and biota in different countries in this basin have varying degrees of environmental contamination and effects on wildlife and humans. The Pacific Rim countries play a pivotal role in governing global POC contamination and resulting harmful health effects. Because articles on POCs and their effect on environment and health are published in a large number of different journals, it is useful to have a book that includes original papers and reviews on the latest advances by well-known scientists in the field, especially focusing on the countries in the Pacific Rim. The two volumes of this book satisfy this need. Topics covered in Volume 1 include an overview of POCs contamination status and trends in the Pacific Basin Countries; human exposure to brominated flame retardants; POCs in sediments, soil and atmosphere of South Korea; and new research on sequestration and redistribution of emerging and classical persistent organic pollutants by polystyrene. The collection of chapters in these volumes may serve as a reasonable representation of current and future trends of POCs in the Pacific Basin countries. It is hoped that the book can inspire students and researchers, as well as professionals, to facilitate the understanding of the environmental and biological behavior of these persistent chemicals and to help in the development of strategies and practices for protecting the global environment for future generations.

This issue of Clinics in Geriatric Medicine, devoted to Geriatric Oncology, is guest edited by Drs. Harvey J. Cohen and Arati V. Rao of Duke University Medical Center. Articles in this issue include: Cancer and Aging: General Principles, Biology and Geriatric Assessment; Cancer Screening in the Elderly; Cancer Survivorship: Management of Long-term Toxicities; Socioeconomic Considerations and Shared Care Models of Older Cancer Care; Palliative Care and Symptom Management; Management of Prostate Cancer in the Elderly; Management of Breast Cancer in the Elderly; Management of Lung Cancer in the Elderly; Colorectal Cancer in the Elderly; Myelodysplastic Syndrome and Acute Myeloid Leukemia in the Elderly; Chronic Lymphocytic Leukemia and Other Lymphoproliferative Disorders; and Monoclonal Gammopathies and Multiple Myeloma in the Elderly.

Combined cycle power plants are one of the most promising ways of improving fossil-fuel and biomass energy production. The combination of a gas and steam turbine working in tandem to produce power makes this type of plant highly efficient and allows for CO2 capture and sequestration before combustion. This book provides a comprehensive review of the design, engineering and operational issues of a range of advanced combined cycle plants.
After introductory chapters on basic combined cycle power plant and advanced gas turbine design, the book reviews the main types of combined cycle system. Chapters discuss the technology, efficiency and emissions performance of natural gas-fired combined cycle (NGCC) and integrated gasification combined cycle (IGCC) as well as novel humid air cycle, oxy-combustion turbine cycle systems. The book also reviews pressurised fluidized bed combustion (PFBC), externally fired combined cycle (EFCC), hybrid fuel cell turbine (FC/GT), combined cycle and integrated solar combined cycle (ISCC) systems. The final chapter reviews techno-economic analysis of combined cycle systems.
With its distinguished editor and international team of contributors, Combined cycle systems for near-zero emission power generation is a standard reference for both industry practitioners and academic researchers seeking to improve the efficiency and environmental impact of power plants.
Provides a comprehensive review of the design, engineering and operational issues of a range of advanced combined cycle plantsIntroduces basic combined cycle power plant and advanced gas turbine design and reviews the main types of combined cycle systemsDiscusses the technology, efficiency and emissions performance of natural gas-fired combined cycle (NGCC) systems and integrated gasification combined cycle (IGCC) systems, as well as novel humid air cycle systems and oxy-combustion turbine cycle systems

Neurostimulation for Epilepsy: Advances, Applications and Opportunities comprehensively reviews the diverse array of neurostimulation technologies currently in use and development for the treatment of epilepsy. The book covers basic research on mechanisms of neurostimulation, technical features of various FDA-approved and investigational devices for neurostimulation, clinical applications and programming considerations of these devices, and emerging insights and research based on data derived from these devices. It provides a contemporary assessment of neurostimulation in epilepsy, one that reveals recent progress in clinical applications and outcomes, fundamental questions that remain unanswered in the field, and future directions and considerations in developing next-generation devices.

Artificial Intelligence, Volume 49 in the Handbook of Statistics series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Chapters in this new release include AI Teacher-Student based Adaptive Structural Deep Learning Model and Its Estimating Uncertainty of Image Data, Machine-derived Intelligence: Computations Beyond the Null Hypothesis, Object oriented basis of artificial intelligence methodologies I in Judicial Systems in India, Artificial Intelligence in Systems Biology, Machine-Learning in Geometry and Physics, Innovation and Machine Learning: Crowdsourcing Open-Source Natural Language Processing (NLP) Algorithms to Advance Public Health Surveillance, and more. Other chapters cover Learning and identity testing of Markov chains, Data privacy for machine learning and statistics, and The interface between AI and Mathematics.

Neurotoxicity of Halogenated Organic Compounds, Volume 10 covers three groups of Halogenated Organic Compounds (Chlorinated, Brominated, and Fluorinated Compounds) that are legacy and emerging contaminants, providing background information, characteristics, physicochemical properties, environmental contamination, and human exposure. Specific chapters covered in this release include Perspective on Halogenated Organic Compounds, The Neurotoxicity of Polychlorinated Biphenyls (PCBs), Neuroendocrine Effects of Polychlorinated Biphenyls (PCBs), Mechanisms of PCB Neurotoxicity: AHR and THR Dogma meet RYR reality, Microbiome and the Neurotoxicity of Brominated Flame Retardants (BFRs), and much more. Other chapters cover Neuroendocrine Effects of Brominated Flame Retardants (BFRs), Focused on Polybrominated Diphenyl Ethers (PBDEs), Neurochemical Effects of Halogenated Organic Compounds: Possible Mode(s) of action and Structure-Activity Relationships, The Neurotoxic Effects of Perfluoroalkyl Substances (PFAS) in Animal Models and Human Cohorts, Neurochemical Mechanisms of Perfluoroalkyl Substances (PFAS) Neurotoxic Action, and Future Directions and Regulatory aspects of Halogenated Organic Compounds.

Water Treatment Using Engineered Carbon Nanotubes provides complete and detailed information on carbon nanotubes for wastewater treatment, covering preparation, properties, and application. The book begins by introducing the cross-disciplinary fundamentals of pollutants, water treatment, and carbon-based nanomaterials, followed by chapters focusing on the adsorption mechanisms, properties, modelling, and preparation techniques for carbon nanotube-based materials in the context of wastewater treatment. The subsequent sections of the book focus on specific applications of carbon nanotubes in removal of pollutants and as catalysts of co-catalysts for water treatment. Finally, other novel applications, key challenges, and research trends are discussed. This is a valuable resource for researchers and advanced students across nanotechnology, materials science, environmental science, chemical engineering, chemistry, biotechnology, sustainability, and engineering, as well as scientists, engineers, and R&D professionals with an interest in advanced nanomaterials for water treatment and environmental protection.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Diseases and Health Consequences of Air Pollution is part of a series of three volumes of Air Pollution, Adverse Effects, and Epidemiological Impact that focuses on epidemiological studies and diseases attributed to ambient and indoor air pollutants. Each chapter of the book discusses a specific area of diseases that has been link to exposure to indoor and outdoor air pollutants. This coverage includes the health impact to the respiratory, cardiovascular, cerebrovascular, reproductive, and nervous systems and the manifestation of resulting disease from air pollutants like skin conditions, diabetes, and cancer. The book also evaluates the health cost and economic burden of air pollution and offers risk management and solutions to mitigating the health implications of indoor and ambient air pollution.

Health Effects of Indoor Air Pollution is part of a series of three volumes of Air Pollution, Adverse Effects, and Epidemiological Impact. This volume covers the classification of indoor air pollutants and discusses the health impact of indoor pollutants such as bio-aerosol, tobacco smoke, and carbon monoxide. It also examines epidemiological studies and assesses the effect of gaseous pollutants and fine particulate matter (PM) on health. The book includes sources of indoor air pollutants and the exposure and risk management of indoor air pollutants. It also explores “sick building syndrome” which causes acute health and discomfort that appear to be linked to time spent in a building. Occupation exposure such as toxic air pollutants in waste, composting, and water treatment facilities is also covered. Other topics include epidemiology studies, estimating health and cost effects, indoor air quality indices, guidelines, standards, and information networks of indoor air pollutants.

Hybrid Nanomaterials for Sustainable Applications: Case Studies and Applications brings together the latest advances in hybrid nanocomposites and their diverse applications for improved sustainability. The book begins by introducing hybrid nanomaterials, synthesis strategies, and approaches to production for engineering applications. Subsequent sections provide chapters on key application areas, including water purification, nanobiotechnologies, energy storage, and biomedicine, presenting approaches for sustainable application for each usage. Throughout the book, key challenges are addressed, with case studies used to support implementation and improve end applications. This is a valuable resource for researchers and advanced students in nanotechnology, polymer science, sustainable materials, chemistry, chemical engineering, environmental science, and materials engineering, as well as industrial scientists, engineers, and R&D professionals with an interest in hybrid nanomaterials for a range of applications.

Deep Learning, Volume 48 in the Handbook of Statistics series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Generative Adversarial Networks for Biometric Synthesis, Data Science and Pattern Recognition, Facial Data Analysis, Deep Learning in Electronics, Pattern Recognition, Computer Vision and Image Processing, Mechanical Systems, Crop Technology and Weather, Manipulating Faces for Identity Theft via Morphing and Deepfake, Biomedical Engineering, and more.

The COVID-19 pandemic demonstrated the necessity for establishing practical strategic global education collaboration throughout the world. The challenges are serious and come in many forms, including but not limited to educational policies, technology limitations, economic, mental health, linguistic barriers, and power struggles. Undoubtedly, international education has a profound impact on the world community, and both teachers and learners need to equip themselves with global critical ways and skills to navigate all kinds of challenges and bring about positive change in the world. The Role of Educators as Agents and Conveyors for Positive Change in Global Education highlights the role of educators as agents and conveyors for positive change in local, regional, and global arenas. As such, it analyzes various conventional and modern educational and learning theories and teaching pedagogies to promote global citizenship among students and teachers. Covering key topics such as learning engagement, curriculum, and online learning, this reference work is ideal for higher education faculty, administrators, researchers, practitioners, academicians, instructors, and students.

Advancements in Bayesian Methods and Implementation, Volume 47 in the Handbook of Statistics series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Fisher Information, Cramer-Rao and Bayesian Paradigm, Compound beta binomial distribution functions, MCMC for GLMMS, Signal Processing and Bayesian, Mathematical theory of Bayesian statistics where all models are wrong, Machine Learning and Bayesian, Non-parametric Bayes, Bayesian testing, and Data Analysis with humans, Variational inference or Functional horseshoe, Generalized Bayes.