This book offers new empirical research and policy-relevant care practices from across the globe to understand the interrelation of care, emotion, and flourishing in the context of acute and persistent crises. From COVID-19 responses around the world to the opioid epidemic in the United States, this volume investigates collective and individual crises as symptoms of underlying systemic pathologies. Crises require deep engagement with both structure and culture, drawing on interdisciplinary perspectives from sociology, nursing, social work, and psychology. Addressing the multi-level challenges of caregiving in families, schools, organizations, and communities, this book presents examples of research and practice that demonstrate compassion, resilience, productive collaboration, and flourishing. It documents the social conditions and processes that spawn effective solutions and positive emotional and health outcomes, which often occur amid chaos, rapid social change, and substantial suffering. The first section focuses on care, emotions, and flourishing in healthcare and educational contexts to examine nurses, students, and teachers as they respond to enduring and acute crises. Section two turns to community and family contexts to understand how emotions and care intertwine in the flourishing practices of women and communities facing isolation during COVID-19, parents of opioid users, and international efforts to address child abuse and healthy aging. Geographically, the book covers experiences in Canada, Ghana, India, Italy, Sweden, the United Kingdom, and the United States. Each chapter discusses how we can move from managing emotions and coping with crisis to transcending crisis and promoting flourishing. The book includes case studies that illustrate hopeful and successful practices that might help us meet the challenges we face in this moment and move through them with compassion and enhanced flourishing. Examining care across a range of professional contexts, including healthcare, education, community, and family settings, the authors explore similarities and differences in how these contexts shape care practices in light of collective threats and crises. This book is also a valuable contribution to the literatures on health and illness, the sociology of emotions, and the interdisciplinary field of well-being and flourishing.