"Much of life can be understood in rational terms if expressed in the language of chemistry. It is an international language, a language without dialects, a language for all time, a language that explains where we came from, what we are, and where the physical world will allow us to go. Chemical Language has great esthetic beauty and links the physical sciences to the b- logical sciences. " from The Two Cultures: Chemistry and Biology by Arthur Kornberg (Nobel Prize in Physiology and Medicine, 1959) Over the past two centuries, chemistry has evolved from a relatively pure disciplinary pursuit to a position of central importance in the physical and life sciences. More generally, it has p- vided the language and methodology that has unified, integrated and, indeed, molecularized the sciences, shaping our understanding of the molecular world and in so doing the direction, development and destiny of scientific research. The "language of chemistry" referred to by my former Stanford colleague is made up of atoms and bonds and their interactions. It is a s- tem of knowledge that allows us to understand structure and events at a molecular level and increasingly to use that understanding to create new knowledge and beneficial change. The words on this page, for example, are detected by the eye in a series of events, now generally understood at the molecular level.

A best-selling mechanistic organic chemistry text in Germany, this text's translation into English fills a long-existing need for a modern, thorough and accessible treatment of reaction mechanisms for students of organic chemistry at the advanced undergraduate and graduate level. Knowledge of reaction mechanisms is essential to all applied areas of organic chemistry; this text fulfills that need by presenting the right material at the right level.

Das dreibAndige Praktikum PrAparative Organische Chemie beschreibt 570 Versuche zunehmenden Experimentier-Anspruchs in der folgenden Partitionierung:

Organisch-chemisches Grundpraktikum beschreibt grundlegende Synthesetechniken in der Themenfolge des Lehrbuchs a žReaktionsmechanismen - Organische Reaktionen, Stereochemie, moderne Synthesemethoden."

Organisch-chemisches Fortgeschrittenenpraktikum behandelt als Band 2 fortgeschrittene Experimentiertechniken wie das Arbeiten mit empfindlichen Reagenzien und im kleinen MaAstab.

Band 3, Organisch-chemisches Schwerpunktpraktikum, lehrt am Beispiel von Asymmetrischen Katalyse State-of-the-Art-Experimentierkunst.

Jeder Band enthAlt Versuchsvorschriften pur. Jedes PrAparat darin wurde unter Praktikumsbedingungen erfolgreich getestet. Jede Reaktion bzw. Reaktionssequenz, die wir berA1/4cksichtigten, qualifizierte sich A1/4ber das Kriterium, lehrreich zu sein - sowohl in Bezug auf die Schulung des ExperimentiervermAgens als auch im Hinblick auf das Vertraut werden mit der Vielfalt organisch-chemischer StoffumwandlungsmAglichkeiten.

This English edition of a best-selling and award-winning German textbook Reaction Mechanisms: Organic Reactions . Stereochemistry . Modern Synthetic Methods is aimed at those who desire to learn organic chemistry through an approach that is facile to understand and easily committed to memory. Michael Harmata, Norman Rabjohn Distinguished Professor of Organic Chemistry (University of Missouri) surveyed the accuracy of the translation, made certain contributions, and above all adapted its rationalizations to those prevalent in the organic chemistry community in the English-speaking world.

Throughout the book fundamental and advanced reaction mechanisms are presented with meticulous precision. The systematic use of red "electron-pushing arrows" allows students to follow each transformation elementary step by elementary step. Mechanisms are not only presented in the traditional contexts of rate laws and substituent effects but, whenever possible, are illustrated using practical, useful and state-of-the-art reactions. The abundance of stereoselective reactions included in the treatise makes the reader familiar with key concepts of stereochemistry.

The fundamental topics of the book address the needs of upper-level undergraduate students, while its advanced sections are intended for graduate-level audiences. Accordingly, this book is an essential learning tool for students and a unique addition to the reference desk of practicing organic chemists, who as life-long learners desire to keep abreast of both fundamental and applied aspects of our science. In addition, it will well serve ambitious students in chemistry-related fields such as biochemistry, medicinal chemistry and pharmaceutical chemistry.

From the reviews:

"Professor Bruckner has further refined his already masterful synthetic organic chemistry classic; the additions are seamless and the text retains the magnificent clarity, rigour and precision which were the hallmark of previous editions. The strength of the book stems from Professor Bruckner s ability to provide lucid explanations based on a deep understanding of physical organic chemistry and to limit discussion to very carefully selected reaction classes illuminated by exquisitely pertinent examples, often from the recent literature. The panoply of organic synthesis is analysed and dissected according to fundamental structural, orbital, kinetic and thermodynamic principles with an effortless coherence that yields great insight and never over-simplifies. The perfect source text for advanced Undergraduate and Masters/PhD students who want to understand, in depth, the art of synthesis ."
Alan C. Spivey, Imperial College London

"Bruckner s Organic Mechanisms accurately reflects the way practicing organic chemists think and speak about organic reactions. The figures are beautifully drawn and show the way organic chemists graphically depict reactions. It uses a combination of basic valence bond pictures with more sophisticated molecular orbital treatments. It handles mechanisms both from the "electron pushing perspective" and from a kinetic and energetic view. The book will be very useful to new US graduate students and will help bring them to the level of sophistication needed to be serious researchers in organic chemistry."
Charles P. Casey, University of Wisconsin-Madison

"This is an excellent advanced organic chemistry textbook that provides a key resource for students and teachers alike."
Mark Rizzacasa, University of Melbourne, Australia."

Mechanistische UEberlegungen nehmen heute einen festen Platz in der Organischen Chemie ein: Welche Faktoren beeinflussen die Reaktivitat eines Molekuls? Welche typischen Reaktionsprinzipien und -muster gibt es, und in welchen Schritten verlaufen organisch-chemische Reaktionen? Wie lassen sich Reaktionen steuern? Anhand moderner und praparativ nutzlicher Reaktionen erlautert der Autor die Reaktionsprinzipien; klar und verstandlich werden Konzepte herausgearbeitet, stets auch stereochemische Konsequenzen abgeleitet. Der Autor bietet Faustregeln zur Reaktivitatsabschatzung sowie Tips und Tricks fur die Praxis. Die zweifarbige Gestaltung erhoeht die UEbersichtlichkeit und erleichtert das Verfolgen der Mechanismen. In der vorliegenden 3. Auflage wurden nach dem uberwaltigenden Verkaufserfolg der 2. Auflage die Fehler in Text und Grafiken korrigiert und die Literatur nochmals aktualisiert. Der Index eignet sich nun fur eine detaillierte Stichwortsuche.