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The phrase "Life, stress and death" connects three terms, but is
there a biological basis for that? Are there molecules that are
essential to/or mediate these phenomena? This contributory volume
"Mortalin Biology: Life, Stress and Death" is a remarkable
compilation of the research outcomes on the stress protein
mortalin, a member of heat shock 70 family of proteins. The book is
unique as it describes mortalin playing essential role in life,
stress response and death either from cancer, when it becomes
hyperactive or from neuro-degeneration, when it becomes hypoactive.
The book provides up-to-date knowledge on mortalin with respect to
its discovery, structure, evolutionary conservation, function and
signal transduction in different organisms in a simple, but most
comprehensive way, that besides offering an enjoyable and in-depth
reading, prompts the reader to ask further questions to explore
this protein with new ideas, approaches and experiments. Twenty-one
chapters by the world leaders on the specific areas of mortalin
research throw light on its multi-functionality, potentials for
biotechnology, diagnostics and therapeutic values. Avenues of
mortalin biology, yet unexplored, hold immense promises for future,
and reading this volume provides an easy, enthusiastic and
energetic head-on start.
The phrase "Life, stress and death" connects three terms, but is
there a biological basis for that? Are there molecules that are
essential to/or mediate these phenomena? This contributory volume
"Mortalin Biology: Life, Stress and Death" is a remarkable
compilation of the research outcomes on the stress protein
mortalin, a member of heat shock 70 family of proteins. The book is
unique as it describes mortalin playing essential role in life,
stress response and death either from cancer, when it becomes
hyperactive or from neuro-degeneration, when it becomes hypoactive.
The book provides up-to-date knowledge on mortalin with respect to
its discovery, structure, evolutionary conservation, function and
signal transduction in different organisms in a simple, but most
comprehensive way, that besides offering an enjoyable and in-depth
reading, prompts the reader to ask further questions to explore
this protein with new ideas, approaches and experiments. Twenty-one
chapters by the world leaders on the specific areas of mortalin
research throw light on its multi-functionality, potentials for
biotechnology, diagnostics and therapeutic values. Avenues of
mortalin biology, yet unexplored, hold immense promises for future,
and reading this volume provides an easy, enthusiastic and
energetic head-on start.
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