Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Complete coverage of the basis of cancer and molecular biology - from globally recognized experts The Basic Science of Oncology is an accessible and thorough introduction to cancer causation, cancer biology, and the biology underlying cancer treatment. You'll find everything you need to know about the latest critical thinking in oncology, as well ready to apply information about state-of-the-art science and therapeutic applications. Written by leading oncology researchers and clinicians, this is an essential resource for health professionals, students, advanced undergraduates and graduates in biological sciences, and clinicians needing an understanding of cancer cells. Presented in full-color, The Basic Science of Oncology reflects the latest research and developments in the field. Features NEW chapters: Epigenetics and Principles of Genome Regulation and Targeted Cancer Diagnosis and Treatment Thoroughly revised content, with expanded coverage of key topics such as immune system and immunotherapy, tumor growth and metabolism, vaccine development, methods of molecular analysis, tumor environment, and more The most current, evidence-based oncology primer-one that encapsulates the science of cancer causation, cancer biology, and cancer therapy Key insights into molecular and genetic aspects of cancer familiarize you with cancer biology as applied to prognosis and personalized cancer medicine In-depth focus on the discovery, evaluation, and biology of anti-cancer drugs, immunotherapy, and molecularly-targeted agents Up-to-date coverage of the basic science of radiation therapy

A dictionary containing over 1900 biographical notices of Sudanese and foreign persons who died before 1948.

Comprehensive, contemporary, and engaging, Animal Physiology provides evolutionary and ecological context to help students make connections across all levels of physiological scale. One of the major challenges instructors and students face in Animal Physiology is making connections across levels of biological scale. Animal Physiology addresses this challenge by providing ecological and evolutionary context to the study of physiology at all levels of organization: genome, molecular biology, biochemistry, cells, tissues, organs, and organ systems. Hill's inclusion of ecology and evolution helps readers gain a holistic perspective on animal function and sets Animal Physiology apart from texts that focus more narrowly on physiology. Hill's Animal Physiology is trusted by instructors and students because of its authoritative, current, engaging, and lavishly illustrated presentation.

This title was first published in 2003. Donald Cardwell's interest in the inter-relationships between science, technology, education and society are exemplified in the selection of his studies and essays brought together here. The first section deals with the rise of scientific education in Britain, comparing it with that on the Continent. The next studies explore the development of the scientific understanding of power, especially steam power, and its application in the new technologies of the Industrial Revolution. The final section looks at learned societies, and in particular at Manchester, making explicit a theme running through many of the articles - the reasons why science, society and education came together to make this city what he called 'the centre of the industrial revolution'.

The twenty-first-century psychotherapist can no longer be constrained by specific schools of practice or limited reservoirs of knowledge. But this new "era of information" needs to be integrated and made manageable for every practitioner. This book helps therapists learn more about this new knowledge and how to apply it effectively. In this single-volume learning resource, Richard Hill and Matthew Dahlitz introduce practitioners to the many elements that create our psychology. From basic neuroscience to body-brain systems and genetic processes, therapists will discover how to become more "response-able" to their clients. Topics include neurobiology, genetics, key therapeutic practices to treat anxiety, depression, trauma and other disorders; memory; mirror neurons and empathy, and more. All are presented with case studies and treatment applications.

The indie game developer's complete guide to running a studio. The climate for the games industry has never been hotter, and this is only set to continue as the marketplace for tablets, consoles and phones grow. Seemingly every day there is a story of how a successful app or game has earned thousands of downloads and revenue. As the market size increases, so does the number of people developing and looking to develop their own app or game to publish. The Indie Game Developer Handbook covers every aspect of running a game development studio from the initial creation of the game through to completion, release and beyond. Accessible and complete guide to many aspects of running a game development studio from funding and development through QA, publishing, marketing, and more. Provides a useful knowledge base and help to support the learning process of running an indie development studio in an honest, approachable and easy to understand way. Case studies, interviews from other studies and industry professionals grant an first-hand look into the world of indie game development

This title was first published in 2003. Donald Cardwell's interest in the inter-relationships between science, technology, education and society are exemplified in the selection of his studies and essays brought together here. The first section deals with the rise of scientific education in Britain, comparing it with that on the Continent. The next studies explore the development of the scientific understanding of power, especially steam power, and its application in the new technologies of the Industrial Revolution. The final section looks at learned societies, and in particular at Manchester, making explicit a theme running through many of the articles - the reasons why science, society and education came together to make this city what he called 'the centre of the industrial revolution'.

A dictionary containing over 1900 biographical notices of Sudanese and foreign persons who died before 1948.

This book provides a valuable reference for digital forensics practitioners and cyber security experts operating in various fields of law enforcement, incident response and commerce. It is also aimed at researchers seeking to obtain a more profound knowledge of Digital Forensics and Cybercrime. Furthermore, the book is an exceptional advanced text for PhD and Master degree programmes in Digital Forensics and Cyber Security. Each chapter of this book is written by an internationally-renowned expert who has extensive experience in law enforcement, industry and academia. The increasing popularity in the use of IoT devices for criminal activities means that there is a maturing discipline and industry around IoT forensics. As technology becomes cheaper and easier to deploy in an increased number of discrete, everyday objects, scope for the automated creation of personalised digital footprints becomes greater. Devices which are presently included within the Internet of Things (IoT) umbrella have a massive potential to enable and shape the way that humans interact and achieve objectives. These also forge a trail of data that can be used to triangulate and identify individuals and their actions. As such, interest and developments in autonomous vehicles, unmanned drones and 'smart' home appliances are creating unprecedented opportunities for the research communities to investigate the production and evaluation of evidence through the discipline of digital forensics.

This textbook describes the hands-on application of data science techniques to solve problems in manufacturing and the Industrial Internet of Things (IIoT). Monitoring and managing operational performance is a crucial activity for industrial and business organisations. The emergence of low-cost, accessible computing and storage, through Industrial Digital Technologies (IDT) and Industry 4.0, has generated considerable interest in innovative approaches to doing more with data. Data science, predictive analytics, machine learning, artificial intelligence and general approaches to modelling, simulating and visualising industrial systems have often been considered topics only for research labs and academic departments. This textbook debunks the mystique around applied data science and shows readers, using tutorial-style explanations and real-life case studies, how practitioners can develop their own understanding of performance to achieve tangible business improvements. All exercises can be completed with commonly available tools, many of which are free to install and use. Readers will learn how to use tools to investigate, diagnose, propose and implement analytics solutions that will provide explainable results to deliver digital transformation.

Artist Kent Monkman's all-encompassing project, Shame and Prejudice: A Story of Resilience, takes viewers on a journey through Canada's history, starting in the present and going back to before Canadian confederation. Throughout the book there are clever, albeit controversial, commentaries told by Monkman's genderfluid, time-travelling, supernatural alter-ego Miss Chief Eagle Testickle. Her narratives take viewers through the history of New France and the fur trade, the nineteenth-century dispossession of First Nations lands through Canadian colonial policies, the horrors of the residential school system, and modern First Nations experiences in urban environments. Shame and Prejudice challenges predominant narratives of Canadian history and honours the resilience of First Nations peoples. This book accompanies Monkman's largest solo exhibition to date, which is currently travelling across Canada at venues including the Art Museum at the University of Toronto, the Winnipeg Art Gallery, the Glenbow Museum in Calgary, and the Museum of Anthropology in Vancouver. The exhibition includes the artist's own paintings, drawings, and sculptural works, which form a dialogue with historical artefacts and artworks borrowed from museums and private collections across Canada. The book is trilingual with all text in English, French and Cree.

This book provides a valuable reference for digital forensics practitioners and cyber security experts operating in various fields of law enforcement, incident response and commerce. It is also aimed at researchers seeking to obtain a more profound knowledge of Digital Forensics and Cybercrime. Furthermore, the book is an exceptional advanced text for PhD and Master degree programmes in Digital Forensics and Cyber Security. Each chapter of this book is written by an internationally-renowned expert who has extensive experience in law enforcement, industry and academia. The increasing popularity in the use of IoT devices for criminal activities means that there is a maturing discipline and industry around IoT forensics. As technology becomes cheaper and easier to deploy in an increased number of discrete, everyday objects, scope for the automated creation of personalised digital footprints becomes greater. Devices which are presently included within the Internet of Things (IoT) umbrella have a massive potential to enable and shape the way that humans interact and achieve objectives. These also forge a trail of data that can be used to triangulate and identify individuals and their actions. As such, interest and developments in autonomous vehicles, unmanned drones and 'smart' home appliances are creating unprecedented opportunities for the research communities to investigate the production and evaluation of evidence through the discipline of digital forensics.

The indie game developer's complete guide to running a studio. The climate for the games industry has never been hotter, and this is only set to continue as the marketplace for tablets, consoles and phones grow. Seemingly every day there is a story of how a successful app or game has earned thousands of downloads and revenue. As the market size increases, so does the number of people developing and looking to develop their own app or game to publish. The Indie Game Developer Handbook covers every aspect of running a game development studio-from the initial creation of the game through to completion, release and beyond. Accessible and complete guide to many aspects of running a game development studio from funding and development through QA, publishing, marketing, and more. Provides a useful knowledge base and help to support the learning process of running an indie development studio in an honest, approachable and easy to understand way. Case studies, interviews from other studies and industry professionals grant an first-hand look into the world of indie game development

This professional guide and reference examines the challenges of assessing security vulnerabilities in computing infrastructure. Various aspects of vulnerability assessment are covered in detail, including recent advancements in reducing the requirement for expert knowledge through novel applications of artificial intelligence. The work also offers a series of case studies on how to develop and perform vulnerability assessment techniques using start-of-the-art intelligent mechanisms. Topics and features: provides tutorial activities and thought-provoking questions in each chapter, together with numerous case studies; introduces the fundamentals of vulnerability assessment, and reviews the state of the art of research in this area; discusses vulnerability assessment frameworks, including frameworks for industrial control and cloud systems; examines a range of applications that make use of artificial intelligence to enhance the vulnerability assessment processes; presents visualisation techniques that can be used to assist the vulnerability assessment process. In addition to serving the needs of security practitioners and researchers, this accessible volume is also ideal for students and instructors seeking a primer on artificial intelligence for vulnerability assessment, or a supplementary text for courses on computer security, networking, and artificial intelligence.

This professional guide and reference examines the challenges of assessing security vulnerabilities in computing infrastructure. Various aspects of vulnerability assessment are covered in detail, including recent advancements in reducing the requirement for expert knowledge through novel applications of artificial intelligence. The work also offers a series of case studies on how to develop and perform vulnerability assessment techniques using start-of-the-art intelligent mechanisms. Topics and features: provides tutorial activities and thought-provoking questions in each chapter, together with numerous case studies; introduces the fundamentals of vulnerability assessment, and reviews the state of the art of research in this area; discusses vulnerability assessment frameworks, including frameworks for industrial control and cloud systems; examines a range of applications that make use of artificial intelligence to enhance the vulnerability assessment processes; presents visualisation techniques that can be used to assist the vulnerability assessment process. In addition to serving the needs of security practitioners and researchers, this accessible volume is also ideal for students and instructors seeking a primer on artificial intelligence for vulnerability assessment, or a supplementary text for courses on computer security, networking, and artificial intelligence.

This book reviews the theoretical concepts, leading-edge techniques and practical tools involved in the latest multi-disciplinary approaches addressing the challenges of big data. Illuminating perspectives from both academia and industry are presented by an international selection of experts in big data science. Topics and features: describes the innovative advances in theoretical aspects of big data, predictive analytics and cloud-based architectures; examines the applications and implementations that utilize big data in cloud architectures; surveys the state of the art in architectural approaches to the provision of cloud-based big data analytics functions; identifies potential research directions and technologies to facilitate the realization of emerging business models through big data approaches; provides relevant theoretical frameworks, empirical research findings, and numerous case studies; discusses real-world applications of algorithms and techniques to address the challenges of big datasets.

This book reviews the theoretical concepts, leading-edge techniques and practical tools involved in the latest multi-disciplinary approaches addressing the challenges of big data. Illuminating perspectives from both academia and industry are presented by an international selection of experts in big data science. Topics and features: describes the innovative advances in theoretical aspects of big data, predictive analytics and cloud-based architectures; examines the applications and implementations that utilize big data in cloud architectures; surveys the state of the art in architectural approaches to the provision of cloud-based big data analytics functions; identifies potential research directions and technologies to facilitate the realization of emerging business models through big data approaches; provides relevant theoretical frameworks, empirical research findings, and numerous case studies; discusses real-world applications of algorithms and techniques to address the challenges of big datasets.

Over the past two decades, we have witnessed unprecedented innovations in the development of miniaturized electromechanical devices and low-power wireless communication making practical the embedding of networked computational devices into a rapidly widening range of material entities. This trend has enabled the coupling of physical objects and digital information into cyber-physical systems and it is widely expected to revolutionize the way resource computational consumption and provision will occur. Specifically, one of the core ingredients of this vision, the so-called Internet of Things (IoT), demands the provision of networked services to support interaction between conventional IT systems with both physical and artificial objects. In this way, IoT is seen as a combination of several emerging technologies, which enables the transformation of everyday objects into smart objects. It is also perceived as a paradigm that connects real world with digital world. The focus of this book is exactly on the novel collective and computational intelligence technologies that will be required to achieve this goal. While, one of the aims of this book is to discuss the progress made, it also prompts future directions on the utilization of inter-operable and cooperative next generation computational technologies, which supports the IoT approach, that being an advanced functioning towards an integrated collective intelligence approach for the benefit of various organizational settings.

This book describes the landscape of cloud computing from first principles, leading the reader step-by-step through the process of building and configuring a cloud environment. The book not only considers the technologies for designing and creating cloud computing platforms, but also the business models and frameworks in real-world implementation of cloud platforms. Emphasis is placed on "learning by doing," and readers are encouraged to experiment with a range of different tools and approaches. Topics and features: includes review questions, hands-on exercises, study activities and discussion topics throughout the text; demonstrates the approaches used to build cloud computing infrastructures; reviews the social, economic, and political aspects of the on-going growth in cloud computing use; discusses legal and security concerns in cloud computing; examines techniques for the appraisal of financial investment into cloud computing; identifies areas for further research within this rapidly-moving field.

This book provides a clear and thorough account of the process leading up to the revision of the International Telecommunication Regulations (ITRs) one of the four treaties administered by the ITU. The author's inside view of the events and his legal analysis of the new ITRs, are different from that what has been aired in most other accounts to date. His systematic approach shows how much of the criticism of the WCIT-12 process and of the ITRs themselves, is unjustified. This book provides the most accurate view to date of what theITRs really mean and of what really happened at WCIT-12, which was undoubtedly a key event in the history of telecommunication policy and which is likely to have significant long-term effects.

The book covers in some detail the events leading to the non-signature of the treaty by a significant number of states, outlines possible consequences of that split between states, and offers possible ways forward. The book includes a detailed article-by-article analysis of the new ITRs, explaining their implications and concludes with recommendations for national authorities. It concludes with an analysis of events from the point of view of dispute resolution theory, offering suggestions for how to avoid divisive outcomes in the future.

"This is an excellent book, and quite rich and comprehensive. The topic is important and the book will surely be of interest to regulators, diplomats, policy experts, and all those who participated in WCIT. The author is uniquely qualified to write an analysis of the new ITRs and an account of the Conference. This book will be a good reference for the next Plenipotentiary Conference to be held in 2014 which is going to discuss follow-up to WCIT-12." Naser al-Rashedi, United Arab Emirates.

"This is an authoritative expert account of a moment of high significance for vital issues with respect to international networks." Professor Dan Schiller, University of Illinois.

"This is an excellent and timely work." Professor Ian Walden, Queen Mary, University of London.

"Interested persons, businesses and governments can draw their policies from the assessments of a telecommunications insider as presented in this book.

The manifold arguments enlightening the interpretation of the provisions of the ITRs might become an invaluable guidance for those who apply the ITRs in the future."

Professor Dr. Rolf H. Weber, University of Zurich."

This important text provides a single point of reference for state-of-the-art cloud computing design and implementation techniques. The book examines cloud computing from the perspective of enterprise architecture, asking the question; how do we realize new business potential with our existing enterprises? Topics and features: with a Foreword by Thomas Erl; contains contributions from an international selection of preeminent experts; presents the state-of-the-art in enterprise architecture approaches with respect to cloud computing models, frameworks, technologies, and applications; discusses potential research directions, and technologies to facilitate the realization of emerging business models through enterprise architecture approaches; provides relevant theoretical frameworks, and the latest empirical research findings.

Over the past two decades, we have witnessed unprecedented innovations in the development of miniaturized electromechanical devices and low-power wireless communication making practical the embedding of networked computational devices into a rapidly widening range of material entities.
This trend has enabled the coupling of physical objects and digital information into cyber-physical systems and it is widely expected to revolutionize the way resource computational consumption and provision will occur. Specifically, one of the core ingredients of this vision, the so-called Internet of Things (IoT), demands the provision of networked services to support interaction between conventional IT systems with both physical and artificial objects. In this way, IoT is seen as a combination of several emerging technologies, which enables the transformation of everyday objects into smart objects. It is also perceived as a paradigm that connects real world with digital world.
The focus of this book is exactly on the novel collective and computational intelligence technologies that will be required to achieve this goal. While, one of the aims of this book is to discuss the progress made, it also prompts future directions on the utilization of inter-operable and cooperative next generation computational technologies, which supports the IoT approach, that being an advanced functioning towards an integrated collective intelligence approach for the benefit of various organizational settings.

This book constitutes the proceedings of the 19th International Conference on Conceptual Structures, ICCS 2011, held in Derby, UK, in July 2011. The 18 full papers and 4 short papers presented together with 12 workshop papers were carefully reviewed and selected for inclusion in the book. The volume also contains 3 invited talks. ICCS focuses on the useful representation and analysis of conceptual knowledge with research and business applications. It advances the theory and practice in connecting the user's conceptual approach to problem solving with the formal structures that computer applications need to bring their productivity to bear. Conceptual structures (CS) represent a family of approaches that builds on the successes of artificial intelligence, business intelligence, computational linguistics, conceptual modelling, information and Web technologies, user modelling, and knowledge management. Two of the workshops contained in this volume cover CS and knowledge discovery in under-traversed domains and in task specific information retrieval. The third addresses CD in learning, teaching and assessment.

This volume offers a close look at four cases of indigenous language revitalization: Maori in Aotearoa/New Zealand, Sami in Scandinavia, Hnahno in Mexico and Quechua and other indigenous languages in Latin America. Essays by experts from each case are in turn discussed in international perspective by four counterpart experts.