This timely book emphasizes the importance of regulation in enabling and channelling innovation at a time when technology is increasingly embedded in healthcare. It considers the adequacy of current regulatory approaches, identifying apparent gaps, risks and liabilities, and discusses how these might be collectively addressed. The authors present possible solutions that balance the protection and promotion of public trust in healthcare against enabling technological progress and disruptive innovation. Offering both a theoretical and practical approach to challenges at the intersection of healthcare, law and technology, this thought-provoking book explores broad questions of regulation and innovation before analysing contextual applications of these topics. It moves from a wide-ranging consideration of the polycentric and changing nature of health regulation through to a more specific examination of topics including patient consent, the role of device representatives, privacy, artificial intelligence and big data. Providing an international perspective, Technology, Innovation and Healthcare will be a valuable resource for scholars and students of health law, innovation, technology law, law and development and law and society. It will also be of benefit to lawyers, healthcare professionals, technology developers and policy makers, seeking to better integrate technology with healthcare.

A uniquely engaging description of the mechanics of the guitar, for engineers and craftsmen alike. Clearly written in a conceptual language, it provides readers with an understanding of the dynamic behavior of the instrument, including structural and component dynamics, and various analytical models, such as discrete, finite element, and boundary element models. The text also covers manufacturing processes, including both handmade and mass produced instruments.

The year is 1992 and Delaware's tumultuous gubernatorial debate is interrupted by an inspiring speech from a humble citizen named Karl Bontrager. After the speech, the consequences for Karl are severe: he is immediately fired from his job and becomes the target of media frenzy. Even though the news media is responsible for fueling a riot in his neighborhood, some political chicanery lands an innocent Karl in jail for creating a public disturbance.

But Karl's inspirational speech has awakened the public. Concerned citizens, neighbors, Karl's granddaughter and some of her college classmates converge on the jail and demand Karl's release. Just as the governor issues an executive order to release him, the startled jailer tells the crowd that Karl is not there.

The situation that ensues in Delaware has far more international and political consequences than anyone had imagined. A world away, the Soviet Union has become a struggling Commonwealth of Independent States. Faced with his own dilemma, the director of a former Soviet research facility is confronted by the prospect of losing many of his nuclear technicians to a wealthy dictatorship.

Featuring chapters on physics, structure, sound and design specifics, "Technology of the Guitar" also includes coverage of historical content, composition of strings and their effects on sound quality, and important designs. Additionally, author Mark French discusses case studies of historically significant and technologically innovative instruments.

This is a complete reference useful for a broad range of readers including guitar manufacturer employees, working luthiers, and interested guitar enthusiasts who do not have a science or engineering background.

"

Stained glass is arguably the most appealing of the achievements of the medieval craftsman, synthesizing monumental painting with the best of medieval architecture, but it is also the least-understood of the medieval arts. Drawing upon recent research in English medieval art-historical studies, "English Medieval Stained Glass" is a comprehensive survey of the art and business of producing stained glass windows, intended to both stimulate further research and to heighten awareness of the need to preserve this fragile art form. It considers stained glass in relation to architecture and other arts and, by examining contemporary documents, it throws valuable light on workshop organization, prices, patronage and iconography. Stained glass attracted outstanding craftsmen who were in the forefront of the main artistic innovations in English medieval art. Their significance is highlighted in this study which also makes use of the plentiful documentary material which throws light on workshop organization and practice, the role of patrons and the important contribution made by stained glass to our knowledge of medieval religions, beliefs and cults.

We all have these. Sometimes, they can be the most wonderful treasure this world has to offer. At other times, they can break your heart. I'm talking about relationships. Everybody has a myriad of different relationships in this adventure called life. Each relationship has its own dynamics, its own foibles, and its own language. We interact with parents, children, siblings, co-workers, spouses, authority, and, for some, even God. The greatest resource of joy, progress, hope, and prosperity is in connections with each other.

But the problem is that the way we develop, sustain, and communicate in relationships is unhealthy. The reason they are unhealthy is because we as individuals bring error into them from the past and from harmful views of ourselves. If you can't think healthy about yourself, how can you interrelate with others in beneficial relationships? How can you have a strong family and an intimate love life if you don't know how to communicate or meet each other's needs? What would be the purpose of building friendships if you don't know how to nurture and sustain them?

This book is designed to answer all those questions and more. Each chapter builds on how to improve yourself, your self-image, and the relationships around you. You will discover from documented research how your brain works in diverse situations, the different ways you handle conflict, how to communicate effectively with others, and how to build the theme of "Us-ness" in life's important relationships and much more.

Fresh examinations of one of the most important church furnishings of the middle ages. The churches of medieval Europe contained richly carved and painted screens, placed between the altar and the congregation; they survive in particularly high numbers in England, despite being partly dismantled during the Reformation. While these screens divided "lay" from "priestly" jurisdiction, it has also been argued that they served to unify architectural space. This volume brings together the latest scholarship on the subject , exploring in detail numerous aspects of the construction and painting of screens, it aims in particular to unite perspectives from science and art history. Examples are drawn from a wide geographical range, from Scandinavia to Italy.

The first modern study of the medium, this book considers stained glass in relation to architecture and other arts, and by examining contemporary documents, it throws valuable light on workshop organisation, prices and patronage.

From the sternoclavicular joint to the distal phalanx, Skeletal Trauma of the Upper Extremity is a practical, one-volume resource covering all aspects of upper limb trauma and surgery. Comprehensive in scope, it features a multidisciplinary, step-by-step approach to evaluation and management, including concise background information and a detailed focus on practical points and surgical techniques. Written by global experts in traumatology, sports medicine, and shoulder, elbow, and hand surgery, this richly illustrated guide brings you into the operating room with leaders in the field. Offers detailed, practical guidance from the originators and/or masters of each procedure, along with multiple, illustrated surgical technique descriptions. Includes pearls and pitfalls, preoperative evaluation and indications, surgical techniques, rehabilitation, and management of complications. Features tables and figures throughout that clearly demonstrate surgical tips and tricks. Identifies controversial topics and covers current challenges such as arthroscopic coracoclavicular/acromioclavicular joint reconstruction, reverse total shoulder arthroplasty for proximal humerus fracture, total elbow arthroplasty for fracture, interosseous membrane reconstruction of the forearm, and many more. Contains more than 500 high-quality illustrations, including anatomical and surgical illustrations, surgical photographs, ultrasounds, and x-rays. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Featuring chapters on physics, structure, sound and design specifics, Technology of the Guitar also includes coverage of historical content, composition of strings and their effects on sound quality, and important designs. Additionally, author Mark French discusses case studies of historically significant and technologically innovative instruments. This is a complete reference useful for a broad range of readers including guitar manufacturer employees, working luthiers, and interested guitar enthusiasts who do not have a science or engineering background.

This revised 2006 edition, which has also been chosen as the official guide to the Cotswold Way relay race, describes the Cotswold Way from the best vantage point - on foot. This is another title from the Cotswold publisher, Reardon. Recommended by TV's "Wish You Were Here", this is the ultimate walking guide to the Cotswolds, "The Cotswold Way". This long distance walk is famous the world over, and rightly so, for it crosses the Cotswolds showing the land as it is seen best by foot. Written by Mark Richards (well-known long distance walker) in his own very special style pointing out the history behind what is seen, showing the reader in illustration the beauty of the Cotswolds and drawing maps so detailed that it would be difficult to get lost even on purpose!. The maps show both the standard way along with the planned official direction changes making it fully up-to-date and usable for many years to come. It features a cover design from a painting of the Cotswolds by the internationally famous David Bellamy and is the official guide used on "The Cotswold Way Relay Race".

DESCRIPTION In a world where big data is the norm and near-real-time decisions are crucial, machine learning (ML) is a critical component of the data workflow. Machine learning systems can quickly crunch massive amounts of information to offer insights and make decisions in a way that matches or even surpasses human cognitive abilities. These systems use sophisticated computational and statistical tools to build models that can recognize and visualize patterns, predict outcomes, forecast values, and make recommendations. Real-World Machine Learning is a practical guide designed to teach developers the art of ML project execution. The book introduces the day-to-day practice of machine learning and prepares readers to successfully build and deploy powerful ML systems. Using the Python language and the R statistical package, it starts with core concepts like data acquisition and modeling, classification, and regression. Then it moves through the most important ML tasks, like model validation, optimization and feature engineering. It uses real-world examples that help readers anticipate and overcome common pitfalls. Along the way, they will discover scalable and online algorithms for large and streaming data sets. Advanced readers will appreciate the in-depth discussion of enhanced ML systems through advanced data exploration and pre-processing methods. KEY FEATURES Accessible and practical introduction to machine learning Contains big-picture ideas and real-world examples Prepares reader to build and deploy powerful predictive systems Offers tips & tricks and highlights common pitfalls AUDIENCE Code examples are in Python and R. No prior machine learning experience required. ABOUT THE TECHNOLOGY Machine learning has gained prominence due to the overwhelming successes of Google, Microsoft, Amazon, LinkedIn, Facebook, and others in their use of ML. The Gartner report predicts that big data analytics will be a $25 billion market by 2017, and financial firms, marketing organizations, scientific facilities, and Silicon Valley startups are all demanding machine learning skills from their developers.

When Freddie Mercury died in 1991, aged just 45, the world was rocked by the vibrant and flamboyant star's tragic secret that he had been battling AIDS. The announcement of his diagnosis reached them less than 24-hours before his death, shocking his millions of fans, and fully opening the eyes of the world to the destructive and fatal disease. In Somebody to Love, biographers Mark Langthorne and Matt Richards skilfully weave Freddie's pursuit of musical greatness with Queen, his upbringing and endless search for love, with the origins and aftermath of a terrible disease that swept across the world in the 1980s. With brand new perspectives from Freddie's closest friends and fellow musicians, this unique and deeply moving tribute casts a very different light on his death. An intimate read, like Freddie and his art, it will stay with you for a long time to come.

We all have these. Sometimes, they can be the most wonderful treasure this world has to offer. At other times, they can break your heart. I'm talking about relationships. Everybody has a myriad of different relationships in this adventure called life. Each relationship has its own dynamics, its own foibles, and its own language. We interact with parents, children, siblings, co-workers, spouses, authority, and, for some, even God. The greatest resource of joy, progress, hope, and prosperity is in connections with each other.

But the problem is that the way we develop, sustain, and communicate in relationships is unhealthy. The reason they are unhealthy is because we as individuals bring error into them from the past and from harmful views of ourselves. If you can't think healthy about yourself, how can you interrelate with others in beneficial relationships? How can you have a strong family and an intimate love life if you don't know how to communicate or meet each other's needs? What would be the purpose of building friendships if you don't know how to nurture and sustain them?

This book is designed to answer all those questions and more. Each chapter builds on how to improve yourself, your self-image, and the relationships around you. You will discover from documented research how your brain works in diverse situations, the different ways you handle conflict, how to communicate effectively with others, and how to build the theme of "Us-ness" in life's important relationships and much more.

Forty colour plates illustrate some of the finest achievements of medieval painting.