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Cilia are microscopic finger-like cell-surface organelles possessed by a great many eukaryotic organisms, including humans, whose purposes include generating local fluid movements via rhythmic whip-like beating and environmental sensing. Despite intense research efforts since their discovery by van Leeuwenhoek in the 1670's, several key questions regarding ciliary functions, experimental manipulation and in silico imitation remain unanswered. Major justifications for cilia research lie in their involvement in various forms of human disease (ciliopathies) and their ability to instantiate decentralised, asynchronous sensorial-actuation of adjacent matter through modulation of beating characteristics. Further elucidation of these characteristics, which is a problem requiring the combined expertise of mathematicians, computer scientists, engineers and life scientists, will lead to novel biomedical therapies, creation of `smart' actuating surfaces for microfluidics/lab-on-chip applications and a greater understanding of fluid mechanics in real-world scenarios. This lavishly-illustrated anthology presents recent advances in the fields of ciliary investigation, manipulation, emulation, mimesis and modelling from key researchers in their fields: its goal is to explain the state-of-the-art in cilia bioengineering and bio-computation in a uniquely creative, accessible manner, towards encouraging further transdisciplinary work in the field as well as educating a broad spectrum of scientists and lay people. The volume is split into three distinct but interwoven themes: 1. Biology: Biological preliminaries for the study of cilia; the state-of-the-art in genetic engineering of ciliated cells for biomedical purposes; reprogramming of cilia dynamics in live cells. 2. Engineering: Creation of macro cilia robots for object sorting applications; pneumatic cilia for the optimization of fluid motion; electrostatic, magnetic and MEMS cilia for microfluidic mixing; reviews in artificial cilia fabrication, actuation and flow induction methods. 3. Numerical and computational modelling. Analyses of thin film cilia for `lab on chip' microfluidic mixing applications; modelling of gel-based artificial cilia towards simulating dynamic behaviors of responsive cilia layers in complex fluids across a wide range of potential applications.
Wilton Park is a unique phenomenon: part of the Britih Government but academically independent; well-known among policy makers, but with a low public profile; created to help foster democracy in post-war Germany, but now with global reach; a vehicle for international dialogue, never one for British propaganda.
Wilton Park was once a secret camp for interrogating enemy generals during World War II. But it took on its true, unique role in 1946 as a training centre for German prisoners-of-war. This volume tells of its history and the extraordinary life of Heinz Koeppler, its founding father.
Cross Channel Currents explores the understandings and
misunderstandings that make up the Entente Cordiale - the
hundred-year relationship between Britain and France, as well as
the everyday common interests and shared pleasures that give it
substance.
Britain's relationship with its European Community partners has been bedevilled by divergent views about the aim of a political union with federal institutions. Federalism is often depicted in Britain as an alien concept with which the British cannot come to terms. Federal Union shows this view to be false.
This study of European Common Market Community is a clear, readable account of how the market works, what its roots are, what its part is in the movement toward European unity, and what its effect will be on the United States. The Community of Europe has been written from the inside by an acknowledged expert, a Cambridge historian who has been an official of the European Economic Community for six years. It has particular relevance for college courses in contemporary European history, comparative economic systems, economic history, and international relations.
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