Enzymes as Sensors, Volume 589, the latest release in the Methods in Enzymology series, covers a variety of topics, including advances in genetically coded fluorescent sensors, enzymes as sensors, and bioapplications of electrochemical sensors and biosensors. Users will find a comprehensive discussion of timely topics that presents a micro-level delivery of specific content related to the study of enzymes in sensors. New to this edition are highly specialized chapters on integrated strategies for gaining a systems level view of dynamic signaling networks, sensitive protein detection and quantification in paper-based microfluidics for point-of-care, and microneedle enzyme sensor arrays for continuous in vivo monitoring. This state-of-the-art series is ideal for those interested in the latest information on enzymology, with this edition focusing on sensors and their role in enzymes.

An exploration of fashion through the ages that asks what our clothing reveals about ourselves and our society.

Dress codes are as old as clothing itself. For centuries, clothing has been a wearable status symbol; fashion, a weapon in struggles for social change; and dress codes, a way to maintain political control. Merchants dressing like princes and butchers’ wives wearing gem-encrusted crowns were public enemies in medieval societies structured by social hierarchy and defined by spectacle. In Tudor England, silk, velvet, and fur were reserved for the nobility, and ballooning pants called “trunk hose” could be considered a menace to good order. The Renaissance-era Florentine patriarch Cosimo de Medici captured the power of fashion and dress codes when he remarked, “One can make a gentleman from two yards of red cloth.” Dress codes evolved along with the social and political ideals of the day, but they always reflected struggles for power and status. In the 1700s, South Carolina’s “Negro Act” made it illegal for Black people to dress “above their condition.” In the 1920s, the bobbed hair and form-fitting dresses worn by free-spirited flappers were banned in workplaces throughout the United States, and in the 1940s, the baggy zoot suits favored by Black and Latino men caused riots in cities from coast to coast.

Even in today’s more informal world, dress codes still determine what we wear, when we wear it—and what our clothing means. People lose their jobs for wearing braided hair, long fingernails, large earrings, beards, and tattoos or refusing to wear a suit and tie or make-up and high heels. In some cities, wearing sagging pants is a crime. And even when there are no written rules, implicit dress codes still influence opportunities and social mobility. Silicon Valley CEOs wear t-shirts and flip-flops, setting the tone for an entire industry: women wearing fashionable dresses or high heels face ridicule in the tech world, and some venture capitalists refuse to invest in any company run by someone wearing a suit.

In Dress Codes, law professor and cultural critic Richard Thompson Ford presents a “deeply informative and entertaining” (The New York Times Book Review) history of the laws of fashion from the middle ages to the present day, a walk down history’s red carpet to uncover and examine the canons, mores, and customs of clothing—rules that we often take for granted. After reading Dress Codes, you’ll never think of fashion as superficial again—and getting dressed will never be the same.

THE TOP FIVE SUNDAY TIMES BESTSELLER A BOOK OF THE YEAR ROUGH TRADE, THE TIMES, ROLLING STONE, CLASH, MOJO, UNCUT The memoir of international music icon Richard Thompson, co-founder of the legendary folk rock group Fairport Convention. 'I encourage everyone to read this wonderful book.' ELVIS COSTELLO 'Thompson could be said to be an English Dylan - only in some ways he's even better than that.' GUARDIAN Richard Thompson came of age during an extraordinary moment in 1960s Britain - as music began to reflect a great cultural awakening, the guitarist and songwriter co-founded Fairport Convention, ushering in the era of folk rock. An intimate memoir of personal discovery and creative intensity, Beeswing vividly captures the life of an international music icon in a world on the cusp of change 'Gripping . . . A quiet joy of a memoir.' GUARDIAN 'Thompson writes exceptionally well . . . If you love music in all its myriad forms, you'll love this book.' NEW YORK JOURNAL OF BOOKS 'An intimate, revealing tome, Beeswing is the voice of a figure at the heart of the British counter-culture.' CLASH 'Perceptive, lyrical, amiable and seemingly effortless . . . required reading.' CAUGHT BY THE RIVER

"A Meteor of Intelligent Substance""Something was Missing in our Culture, and Here It Is""Liberties is THE place to be. Change starts in the mind." Liberties, a journal of Culture and Politics, is essential reading for those engaged in the cultural and political issues and causes of our time. Liberties features serious, independent, stylish, and controversial essays by significant writers and leaders throughout the world; new poetry; and, introduces the next generation of writers and voices to inspire and impact the intellectual and creative lifeblood of today's culture and politics. This issue of Liberties includes: new work from Nobel Prize winner Mario Vargas Llosa; drawings by Leonard Cohen published for the first time; Mamtimin Ala's essay on China's genocide of the Uyghurs; Jaroslaw Anders' analysis of the crisis in Belarus; Cass R. Sunstein on liberalism inebriated; Richard Thompson Ford on what slavery does and does not explain; Sean Wilentz on the historical strategy of the Republican Party; Benjamin Moser writes about translation as a form of tourism in literary life; Jonathan Zimmerman on the scandal of college teaching; Mark Lilla on cults of innocence and their victims; Helen Vendler on Adrienne Rich; Holly Brewer on race and enlightenment; David Thomson asks, What shall we watch now?; Celeste Marcus (managing editor) on the legend of Alice Neel; Leon Wieseltier (editor) on Zionism's beautiful stubbornness of survival; and new poetry from Ange Mlinko and Shaul Tchernikhovsky, translated by Robert Alter.

Informative, vivid and richly illustrated, this volume explores the history of England's northern borders - the former counties of Northumberland, Cumberland, Durham, Westmorland and the Furness areas of Lancashire - across 1000 years. The book explores every aspect of this changing scene, from the towns and poor upland farms of early modern Cumbria to life in the teeming communities of late Victorian Tyneside. In their final chapters the authors review the modern decline of these traditional industries and the erosion of many of the region's historical characteristics.

The present volume is the product of several years of collaboration at a distance between two people who both knew Yres R. Simon personally and admired his work. The question raised by Simon more than half a century ago, when this book was first published, are still with us: What is the nature of knowledge? What kind of activity is it to know? What is involved in the development of human knowledge? If one had to describe Simon's accomplishment by reducing it to a single point, what he succeeded in showing was that an ontology of knowledge based on common experience disproves all idealism and leads to realism by strictest necessity.

This book is the first to combine interests in two currently popular approaches to language description, both of which are based on the observation of naturally-occurring, as opposed to invented, language. Systemic Functional Linguistics is a theory that focuses on meaning, choice and probability in language and on language as a social phenomenon. Corpus Linguistics is a practice, rather than a theory: a corpus is a large collection of texts that are used as the basis for language description. It is natural that SFL should turn to corpora as a source of information about grammatical preference, probability and variety, and some of the papers in this collection explore this dimension of the interaction between system and corpus. Conversely, corpus linguists have made generalisations about language that contextualize but also challenge the theories of SFL. Some of the papers in the collection expand on this theme. A concluding paper by M.A.K. Halliday responds to the issues raised. The book will therefore be of interest to students and researchers involved in either of these two influential topics in linguistics.

This book is the first to combine interests in two currently popular approaches to language description, both of which are based on the observation of naturally-occurring, as opposed to invented, language. Systemic Functional Linguistics is a theory that focuses on meaning, choice and probability in language and on language as a social phenomenon. Corpus Linguistics is a practice, rather than a theory: a corpus is a large collection of texts that are used as the basis for language description. It is natural that SFL should turn to corpora as a source of information about grammatical preference, probability and variety, and some of the papers in this collection explore this dimension of the interaction between system and corpus. Conversely, corpus linguists have made generalisations about language that contextualize but also challenge the theories of SFL. Some of the papers in the collection expand on this theme. A concluding paper by M.A.K. Halliday responds to the issues raised. This book will therefore be of interest to students and researchers involved in either of these two influential topics in linguistics.

This volume explores the history of England's northern borders - the former counties of Northumberland, Cumberland, Durham, Westmorland and the Furness areas of Lancashire - across 1000 years. For most of them the region was a world of its own, often disrupted by border warfare between England and Scotland yet largely disregarded by the official authorities to south and north. Peace in the 17th century brought prosperity and population growth; a region virtually without wheeled traffic was opened up by turnpike and railway; and the North East grew into one of the dynamic hubs of industrial Britain, with ironworking, shipbuilding and mining prominent among its thriving concerns.

The Royal College of Physicians celebrates its 500th anniversary in 2018, and to observe this landmark is publishing this series of ten books. Each of the books focuses on fifty themed elements that have contributed to making the RCP what it is today, together adding up to 500 reflections on 500 years. Some of the people, ideas, objects and manuscripts featured are directly connected to the College, while others have had an influence that can still be felt in its work. This, the seventh book in the series looks at the history of the Royal College.

This book is open access under a CC BY-NC 4.0 license. The third edition of this indispensable book in radio interferometry provides extensive updates to the second edition, including results and technical advances from the past decade; discussion of arrays that now span the full range of the radio part of the electromagnetic spectrum observable from the ground, 10 MHz to 1 THz; an analysis of factors that affect array speed; and an expanded discussion of digital signal-processing techniques and of scintillation phenomena and the effects of atmospheric water vapor on image distortion, among many other topics. With its comprehensiveness and detailed exposition of all aspects of the theory and practice of radio interferometry and synthesis imaging, this book has established itself as a standard reference in the field. It begins with an overview of the basic principles of radio astronomy, a short history of the development of radio interferometry, and an elementary discussion of the operation of an interferometer. From this foundation, it delves into the underlying relationships of interferometry, sets forth the coordinate systems and parameters to describe synthesis imaging, and examines configurations of antennas for multielement synthesis arrays. Various aspects of the design and response of receiving systems are discussed, as well as the special requirements of very-long-baseline interferometry (VLBI), image reconstruction, and recent developments in image enhancement techniques and astrometric observations. Also discussed are propagation effects in the media between the source and the observer, and radio interference, factors that limit performance. Related techniques are introduced, including intensity interferometry, optical interferometry, lunar occultations, tracking of satellites in Earth orbit, interferometry for remote Earth sensing, and holographic measurements of antenna surfaces. This book will benefit anyone who is interested in radio interferometry techniques for astronomy, astrometry, geodesy, or electrical engineering.

This book is open access under a CC BY-NC 4.0 license. The third edition of this indispensable book in radio interferometry provides extensive updates to the second edition, including results and technical advances from the past decade; discussion of arrays that now span the full range of the radio part of the electromagnetic spectrum observable from the ground, 10 MHz to 1 THz; an analysis of factors that affect array speed; and an expanded discussion of digital signal-processing techniques and of scintillation phenomena and the effects of atmospheric water vapor on image distortion, among many other topics. With its comprehensiveness and detailed exposition of all aspects of the theory and practice of radio interferometry and synthesis imaging, this book has established itself as a standard reference in the field. It begins with an overview of the basic principles of radio astronomy, a short history of the development of radio interferometry, and an elementary discussion of the operation of an interferometer. From this foundation, it delves into the underlying relationships of interferometry, sets forth the coordinate systems and parameters to describe synthesis imaging, and examines configurations of antennas for multielement synthesis arrays. Various aspects of the design and response of receiving systems are discussed, as well as the special requirements of very-long-baseline interferometry (VLBI), image reconstruction, and recent developments in image enhancement techniques and astrometric observations. Also discussed are propagation effects in the media between the source and the observer, and radio interference, factors that limit performance. Related techniques are introduced, including intensity interferometry, optical interferometry, lunar occultations, tracking of satellites in Earth orbit, interferometry for remote Earth sensing, and holographic measurements of antenna surfaces. This book will benefit anyone who is interested in radio interferometry techniques for astronomy, astrometry, geodesy, or electrical engineering.