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Bridging the gap between medical and surgical specialties in
critical care, Textbook of Critical Care, 8th Edition, offers
a practical, multidisciplinary approach to the effective management
of adult and pediatric patients in the ICU. An outstanding
editorial team, led by world-renowned intensivist Dr. Jean-Louis
Vincent, assisted by Dr. Frederick A. Moore and new editors Drs.
Rinaldo Bellomo and John J. Marini, provides
the evidence-based guidance you need to overcome a full
range of practice challenges. A full-color art program, relevant
basic science and key summary points in every chapter, and expert
contributing authors from all over the world make this an
indispensable resource for every member of the critical care team.
Provides a concise, readable understanding of
the pathophysiology of critical illness and new
therapeutic approaches to critical care. Addresses
both medical and surgical aspects in critical care
for adult and pediatric patients in one comprehensive,
easy-to-use reference. Shares the knowledge and expertise of
the most recognized and trusted leaders in the field,
with more international contributing authors than in
previous editions. Covers new information on
procedural and diagnostic ultrasound, prone positioning, ECMO, and
VADs. Discusses key topics such as organ
support, telemedicine, echocardiography, antibiotic stewardship,
antiviral agents, coagulation and anti-coagulation, and
more. Features a wealth of tables, boxes, algorithms,
diagnostic images, and key points that clarify
important concepts and streamline complex information for quick
reference. Includes companion videos and exclusive
chapters online that cover commonly performed
procedures. Takes a multidisciplinary
approach to critical care, with contributions from experts in
anesthesia, surgery, pulmonary medicine, and pediatrics.Â
Enhanced eBook version included with purchase. Your enhanced
eBook allows you to access all of the text, figures, and references
from the book on a variety of devices.Â
Over the last 10 years the syndrome of severe acute renal failure
has progressively changed in its epidemiology. It is now most
frequently seen in critically ill patients, typically in the
context of sepsis and multiorgan failure. This epidemiologic change
has meant that intensive care physicians and nephrologists must now
work in close cooperation at all times and must take many com plex
issues of prevention, pathogenesis, and management into account
that they did not previously have to tackle. Simultaneously, the
last 10 years have seen the development of major technical and
conceptual changes in the field of renal replacement therapy. There
are now previously unavailable therapeutic options that provide
physicians with a flexible and rapidly evolving armamentarium. The
nutrition of these patients, previously limited by the par tial
efficacy of renal replacement therapies, has also become more
aggressive and more in tune with the needs of critically ill
patients. Increased understanding of the pathogenesis of the multi
organ failure syndrome has focused on the role of many soluble
"mediators of injury" (cytokines, leukotrienes, prostanoids etc.).
These molecules are likely to participate in the pathogenesis of
acute renal failure. Their generation and disposal is also affected
by different techniques of artificial renal support."
The 2nd edition of this book describes the recent techniques,
strategies, and drugs that have been demonstrated by multicenter
randomized trials to influence survival in critically ill, defined
as those who have acute failure of at least one organ, due to
either a pathological condition or a medical intervention, and
require intensive care treatment. Each chapter focuses on a
specific procedure, device, or drug. The scope is accordingly wide,
with coverage of topics as diverse as noninvasive mechanical
ventilation, protective ventilation, prone positioning, intravenous
salbutamol in ARDS, high-frequency oscillatory ventilation, mild
hypothermia after cardiac arrest, daily interruption of sedatives,
tranexamic acid, diaspirin cross-linked hemoglobin, albumin, growth
hormone, glutamine supplementation, tight glucose control,
supranormal oxygen delivery, and hydroxyethyl starch in sepsis. The
topics selection was performed with the help of hundreds of
specialists from dozens of countries; they expressed via web if
they agreed or not with these topics and if they used them in their
daily clinical practice. The clear text is supported by "how to do"
sections and "key point" boxes that provide easily accessible
practical information. Written by acknowledged international
experts, Reducing Mortality in Critically Ill Patients is of
interest for a wide variety of specialists, including intensivists,
emergency doctors, and anesthesiologists.
The latest edition of this text is the go-to book on rapid response
systems (RRS). Thoroughly updated to incorporate current principles
and practice of RRS, the text covers topics such as the logistics
of creating an RRS, patient safety, quality of care, evaluating
program results, and engaging in systems research. Edited and
written by internationally recognized experts and innovators in the
field, Textbook of Rapid Response Systems: Concepts and
Implementation, Second Edition is a valuable resource for medical
practitioners and hospital administrators who want to implement and
improve a rapid response system.
Why Critical Care Evolved METs? In early 2004, when Dr. Michael
DeVita informed me that he was cons- ering a textbook on the new
concept of Medical Emergency Teams (METs), I was surprised. At
Presbyterian-University Hospital in Pittsburgh we int- duced this
idea some 15 years ago, but did not think it was revolutionary
enough to publish. This, even though, our fellows in critical care
medicine training were all involved and informed about the
importance of "C- dition C (Crisis)," as it was called to
distinguish it from "Condition A (Arrest). "We thought it absurd to
intervene only after cardiac arrest had occurred, because most
cases showed prior deterioration and cardiac arrest could be
prevented with rapid team work to correct precluding problems. The
above thoughts were logical in Pittsburgh, where the legendary Dr.
Peter Safar had been working since the late 1950s on improving
current resuscitation techniques, ?rst ventilation victims of
apneic from drowning, treatment of smoke inhalation, and so on.
This was followed by external cardiac compression upon
demonstration of its ef?ciency in cases of unexpected sudden
cardiac arrest. Dr. Safar devoted his entire professional life to
improvement of cardiopulmonary resuscitation. He and many others
emphasized the importance of getting the CPR team to o- of-hospital
victims of cardiac arrest as quickly as possible.
This issue of Critical Care Clinics, Guest Edited by Dr. Rinaldo
Bellomo, focuses on Modern Critical Care Endocrinology. Article
topics include: Diabetes insipidus and SIADH in the ICU; Estrogen
therapy in ICU patients; The angiotensin family, ACE and ACE 2;
Angiotensin II in vasodilatory shock; Vasopressin in vasodilatory
shock; Hydrocortisone in vasodilatory shock; Erythropoietin in
trauma and critical illness; HbA1c and permissive hyperglycemia in
diabetic ICU patients; Osteoporosis and the critically ill patient;
New oral agents for the treatment of diabetes; Melatonin in
critical care; The incretins in ICU patients; Hepcidin; Thyroid
hormone therapy in the ICU; and Hormonal therapy in organ donors.
Continuous Renal Replacement Therapy (CRRT) is the standard of care
for management of critically ill patients with acute renal failure.
Part of the Pittsburgh Critical Care series, Continuous Renal
Replacement Therapy provides concise, evidence-based, bedside
guidance about this treatment modality, offering quick reference
answers to clinicians' questions about treatments and situations
encountered in daily practice. Organized into sections on theory,
practice, special situations, and organizational issues, this
volume provides a complete view of CRRT theory and practice. Tables
summarize and highlight key points, and key studies and trials are
included in each chapter. The second edition has been updated to
include a new chapter on the use of biomarkers to aid in patient
selection and timing, extensive revisions on terminology and
nomenclature to match current standards, and the most up-to-date
information on newly developed CRRT machines.
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