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This thorough volume explores recent advances that have
revolutionized the field of precision oncology. The chapters,
contributed by experts in the areas of cancer systems and
integrative biology, provide hands-on guidance toward developing
tools to monitor spatial and temporal changes in tumors, tracking
tumor markers in blood, and ultimately developing precision
medicine to combat cancer in real time. Written for the highly
successful Methods in Molecular Biology series, chapters include
the kind of detailed implementation advice that ensures successful
results. Authoritative and informative, Cancer Systems and
Integrative Biology serves as an invaluable resource for
researchers, pharmaceutical scientists, and oncologists interested
in expanding their knowledge base in the current developments in
cancer research.
This book uses Ludwig Wittgenstein's philosophical methodology to
solve a problem that has perplexed thinkers for thousands of years:
'how come (abstract) mathematics applies so wonderfully well to the
(concrete, physical) world?' The book is distinctive in several
ways. First, it gives the reader a route into understanding
important features of Wittgenstein's writings and lectures by using
his methodology to tackle this long-standing and seemingly
intractable philosophical problem. More than this, though, it
offers an outline of important (sometimes little-known) aspects of
the development of mathematical thought through the ages, and an
engagement of Wittgenstein's philosophy with this and with
contemporary philosophy of mathematics on its own terms. A clear
overview of all this in the context of Wittgenstein's philosophy of
mathematics is interesting in its own right; it is also just what
is needed to solve the problem of mathematics and world.
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