The National Plant Genome Initiative was launched in 1998 as a long-term project to explore DNA structure and function in plants so that useful properties of plants can be understood, improved, and ultimately harnessed to address national needs, including agriculture, nutrition, energy and waste reduction. Experts in the community were asked to consider how to build on current accomplishments in order to address major questions in plant biology and to make recommendations for objectives for the next five-year phase of the Initiative.

The emergence of HIV disease and AIDS, the reemergence of tuberculosis, and the increased opportunity for disease spread through international travel demonstrate the critical importance of global vigilance for infectious diseases. This volume highlights risk factors for the emergence of microbial threats to health, warns against complacency in public health, and promotes early prevention as a cost-effective and crucial strategy for maintaining public health in the United States and worldwide. The volume identifies infectious disease threats posed by bacteria and viruses, as well as protozoans, helminths, and fungi. Rich in information, it includes a historical perspective on infectious disease, with focuses on Lyme disease, peptic ulcer, malaria, dengue, and recent increases in tuberculosis. The panel discusses how "new" diseases arise and how "old" ones resurge and considers the roles of human demographics and behavior, technology and industry, economic development and land use, international travel and commerce, microbial adaptation and change, and breakdown of public health measures in changing patterns of infectious disease. Also included are discussions and recommendations on disease surveillance; vaccine, drug, and pesticide development; vector control; public education and behavioral change; research and training; and strengthening of the U.S. public health system. This volume will be of immediate interest to scientists specializing in all areas of infectious diseases and microbiology, healthy policy specialists, public health officials, physicians, and medical faculty and students, as well as anyone interested in how their health can be threatened by infectious diseases. Table of Contents FRONT MATTER EXECUTIVE SUMMARY 1 BACKGROUND 2 FACTORS IN EMERGENCE 3 ADDRESSING THE THREATS REFERENCES APPENDIXES A TASK FORCES B CATALOG OF EMERGING INFECTIOUS DISEASE AGENTS C GLOBAL RESOURCES FOR INFECTIOUS DISEASE SURVEILLANCE D COMMITTEE AND STAFF BIOGRAPHIES GLOSSARY ACRONYMS AND ABBREVIATIONS INDEX