Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular 'drivers' can be exploited from a therapeutic standpoint with currently available targeted agents. Where applicable, integration of targeted therapies with conventional cytotoxic agents will be considered. This volume will provide a comprehensive summary of molecular characteristics of childhood cancers, and how the changes involved in transformation provide us with opportunities for developing relatively less toxic, but curative, therapies.

"Cancer Genomics" addresses how recent technological advances in genomics are shaping how we diagnose and treat cancer. Built on the historical context of cancer genetics over the past 30 years, the book provides a snapshot of the current issues and state-of-the-art technologies used in cancer genomics. Subsequent chapters highlight how these approaches have informed our understanding of hereditary cancer syndromes and the diagnosis, treatment and outcome in a variety of adult and pediatric solid tumors and hematologic malignancies. The dramatic increase in cancer genomics research and ever-increasing availability of genomic testing are not without significant ethical issues, which are addressed in the context of the return of research results and the legal considerations underlying the commercialization of genomic discoveries. Finally, the book concludes with "Future Directions," examining the next great challenges to face the field of cancer genomics, namely the contribution of non-coding RNAs to disease pathogenesis and the interaction of the human genome with the environment.
Tools such as sidebars, key concept summaries, a glossary, and acronym and abbreviation definitions make this book highly accessible to researchers from several fields associated with cancer genomics.Contributions from thought leaders provide valuable historical perspective to relate the advances in the field to current technologies and literature.

The Year Book of Oncology brings you abstracts of the articles that reported the year's breakthrough developments in oncology, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed! Topics include Supportive Care, Breast Cancer, Gynecologic Cancers, Genitourinary Cancers, Hematologic Malignancies, Thoracic Cancer, Gastrointestinal Cancer and Cancer Biology. The Year Book of Oncology is available annually in November.

The Year Book of Oncology brings you abstracts of the articles that reported the year's breakthrough developments in oncology, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed! Topics include Supportive Care, Breast Cancer, Gynecologic Cancers, Genitourinary Cancers, Hematologic Malignancies, Thoracic Cancer, Gastrointestinal Cancer and Cancer Biology. The Year Book of Oncology is available annually in November.

'The Year Book of Oncology' brings you abstracts of articles that reported breakthrough developments in oncology, selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to practice.

This is the third edition of a well-received compendium of information and guidance on the diagnosis and management of the various oncological diseases that are encountered in children and adolescents. In the new edition a chapter on Rare Tumors was added. For each disease entity, fundamental facts are provided that will be relevant for a range of professionals - hospital physicians, specialist nurses, psycho-oncologists, physiotherapists, family doctors, and pediatricians. Compared with the first edition all chapters have been updated. Throughout, rapid orientation is ensured by the clear, consistent layout and the concise, lucid style. Pediatric Oncology: A Comprehensive Guide is an excellent, easy-to-use reference that belongs on the shelf of every practitioner who encounters or treats malignancies in the pediatric age group. Pediatric Oncology is teamwork Fundamental facts for all those involved in diagnosis and management - even social worker, pedagogic teachers, religious care persons.

This is the third edition of a well-received compendium of information and guidance on the diagnosis and management of the various oncological diseases that are encountered in children and adolescents. In the new edition a chapter on Rare Tumors was added. For each disease entity, fundamental facts are provided that will be relevant for a range of professionals - hospital physicians, specialist nurses, psycho-oncologists, physiotherapists, family doctors and pediatricians. Compared with the first edition all chapters have been updated. Throughout, rapid orientation is ensured by the clear, consistent layout and the concise, lucid style. Pediatric Oncology: A Comprehensive Guide is an excellent, easy-to-use reference that belongs on the shelf of every practitioner who encounters or treats malignancies in the pediatric age group. Pediatric Oncology is teamwork! Fundamental facts for all those involved in diagnosis and management - even social worker, pedagogic teachers, religious care persons.

Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular 'drivers' can be exploited from a therapeutic standpoint with currently available targeted agents. Where applicable, integration of targeted therapies with conventional cytotoxic agents will be considered. This volume will provide a comprehensive summary of molecular characteristics of childhood cancers, and how the changes involved in transformation provide us with opportunities for developing relatively less toxic, but curative, therapies.