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Lipids traditionally have been viewed as serving two functions: to
form cellular membranes and to serve as energy stores. During the
last two decades, a new role for lipids has taken center stage:
lipids can act as signalling molecules. This book deals with a
variety of lipids that have been shown to be messengers. Leading
scientists explore all known lipid classes except steroid hormones.
Researchers and educators in biochemistry as well as in molecular
and cellular biology will appreciate this volume.
Scientists in lipid biochemistry research have increasingly
recognized the role of lipids as signaling molecules, aside from
their importance in forming cellular membranes and storing energy.
This book provides the latest findings on a wide variety of complex
lipids in cells that function either as intracellular or
intercellular messengers. International investigators present
current data on the most extensively studied examples of both
intracellular and intercellular messengers generated from lipids,
and describe their basic mechanisms, which also utilize receptors
in the G-protein-coupled family. The in-depth discussions address
such topics as lipid signaling for protein kinase C activation,
phosphatidic acid and lyso-phosphatidic acid, ceramide as a
messenger, bioactive properties of Sphingosine and structurally
related compounds, platelet-activating factor and PAF-like
mimetics, and prostaglandins and related compounds. Lipid Second
Messengers is an up-to-date reference on developments in the
expanding field of lipid-derived signals and will be of interest to
biochemists, physiologists, pharmacologists, geneticists, and
biologists.
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