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Behavioral and Neural Genetics of Zebrafish assembles the
state-of-the-art methodologies and current concepts pertinent to
their neurobehavioral genetics. Discussing their natural behavior,
motor function, learning and memory, this book focuses on the fry
and adult zebrafish, featuring a comprehensive account of modern
genetic and neural methods adapted to, or specifically developed
for, Danio rerio. Numerous examples of how these behavioral methods
may be utilized for disease models using the zebrafish are
presented, as is a section on bioinformatics and "big-data" related
questions.
Molecular-Genetic and Statistical Techniques for Behavioral and
Neural Research presents the most exciting molecular and
recombinant DNA techniques used in the analysis of brain function
and behavior, a critical piece of the puzzle for clinicians,
scientists, course instructors and advanced undergraduate and
graduate students. Chapters examine neuroinformatics, genetic and
neurobehavioral databases and data mining, also providing an
analysis of natural genetic variation and principles and
applications of forward (mutagenesis) and reverse genetics (gene
targeting). In addition, the book discusses gene expression and its
role in brain function and behavior, along with ethical issues in
the use of animals in genetics testing. Written and edited by
leading international experts, this book provides a clear
presentation of the frontiers of basic research as well as
translationally relevant techniques that are used by
neurobehavioral geneticists.
The first volume in the new Cambridge Handbooks in Behavioral
Genetics series, Behavioral Genetics of the Mouse provides baseline
information on normal behaviors, essential in both the design of
experiments using genetically modified or pharmacologically treated
animals and in the interpretation and analyses of the results
obtained. The book offers a comprehensive overview of the genetics
of naturally occurring variation in mouse behavior, from perception
and spontaneous behaviors such as exploration, aggression, social
interactions and motor behaviors, to reinforced behaviors such as
the different types of learning. Also included are numerous
examples of potential experimental problems, which will aid and
guide researchers trying to troubleshoot their own studies. A
lasting reference, the thorough and comprehensive reviews offer an
easy entrance into the extensive literature in this field, and will
prove invaluable to students and specialists alike.
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