Cancer research has reached a major turning point, and no one is better qualified to explain the past two deacades' dramatic leaps forward in understanding this disease than world-renowned molecular biologist Robert Weinberg, director of the Oncology Research labouratory at the Whitehead Institute in Cambridge, Massachusetts. In One Renegade Cell , Weinberg presents a state-of-the-art account of how cancer begins and how, one day, it will be cured.

In all facets of life, most people strive for success. This could mean getting a promotion to vice-president, making the high school basketball team, having your children grow up to be good citizens, or getting the family together for holidays. Many of the elements of success are likely to include recovering from failure, short and long-term goals, perseverance, focused concentration, coping with adversity and keeping confident despite obstacles. To be successful requires many of these attributes and some people might consider them to be ingredients of mental toughness. But what is mental toughness? Let's look at the following examples and you can decide whether the person is mentally tough or not. A basketball player is injured and despite the fact that he may re-injure himself and hurt his long-term career, he decides to play in the championship game to help his teammates. A businesswoman is feeling really sick but she has a big presentation scheduled for today. Even though she might not be at her very best she "sucks it up" takes some medicine and goes into work to deliver her presentation. Are these examples of mental toughness or not? Would your conclusion be any different based on the outcome of the situation? For example would you say the businesswoman was mentally tough if she gave a great presentation but should have stayed home if, due to her illness, gave a poor presentation? These are difficult decisions, and people will typically come to different conclusions concerning what is mental toughness.In this book, I will provide evidence regarding the meaning of mental toughness. Its component will be broken down and tips for how to build mental toughness will be provided. So get started on the journey of understanding mental toughness and taking concrete steps to become more mentally tough.

In the 1980s, capillary electrophoresis (CE) joined high-performance liquid chromatography (HPLC) as the most powerful separation technique available to analytical chemists and biochemists. Published research using CE grew from 48 papers in the year of commercial introduction (1988) to 1200 in 1997. While only a dozen major pharmaceutical and biotech companies have reduced CE to routine practice, the applications market is showing real or potential growth in key areas, particularly in the DNA marketplace for genomic mapping and forensic identification. For drug development involving small molecules (including chiral separations), one CE instrument can replace 10 liquid chromatographs in terms of speed of analysis. CE also uses aqueous rather than organic solvents and is thus environmentally friendlier than HPLC. The second edition of Practical Capillary Electrophoresis has been extensively reorganized and rewritten to reflect modern usage in the field, with an emphasis on commercially available apparatus and reagents. This authoritative and very comprehensible treatment builds on the author's extensive experience as an instructor of short courses for the American Chemical Society and for industry.
Key Features
* Illustrated with detailed diagrams of electrophoretic phenomena
* Offers step-by-step methods development schemes
* Presents techniques for developing quantitative, robust, and precise methods
* Includes an extensive troubleshooting guide
* Updates and greatly expands on the first edition-more than 50% of the text is new
* Written by an internationally recognized scientist who is an instructor for American Chemical Society short courses on HPCE

Tracing the evolving nature of popular and official beliefs about the purported nature of the Jews from the 18th century onwards, Russia and the Jewish Question explores how perceptions of Jews in late Imperial Russia and the Soviet Union shaped the regimes’ policies toward them. In so doing Robert Weinberg provides a fruitful lens through which to investigate the social, economic, political, and cultural developments of modern Russia. Here, Weinberg reveals that the ‘Jewish Question’ – and, by extension anti-Semitism – emerged at the end of the 18th century when the partitions of Poland made hundreds of thousands of Jews subjects of the Russian crown. He skillfully argues the phrase itself implies the singular nature of Jews as a group of people whose religion, culture, and occupational make-up prevent them from fitting into predominantly Christian societies. The book then expounds how other characteristics were associated with the group over time: in particular, debates about rights of citizenship, the impact of industrialization, the emergence of the nation-state, and the proliferation of new political ideologies and movements contributed to the changing nature of the ‘Jewish Question’. Its content may have not remained static, but its purpose consistently questions whether or not Jews pose a threat to the stability and well-being of the societies in which they live and this, in a specifically Russian context, is what Weinberg examines so expertly.

Classic horror stories from the pulps, including work by Robert E. Howard, Seabury Quinn, G.G. Pendarves, and many more.

Weinberg's work is so ground-breaking, his research so arduous, and his precursors in this field so generally unhelpful that we must regard this as charting virtually unexplored waters. There is nothing really to compare the book to, and there is not likely to be a more complete such book in the near future. Weinberg deserves the thanks of anyone seriously interested in what we might call the cultural history of SF, and his book belongs in any collection that purports to represent that history. "Science Fiction StudieS"

While there have been numerous books published over the past few decades on the subject of science fiction and fantasy books and movies, almost no attention has been paid to science fiction and fantasy artists. Although a number of picture books emerged in recent years, only a limited number have provided any significant information. This comprehensive biographical dictionary represents one of the first research efforts in the field of science fiction art. It is not an art book, but rather a book about artists. As one of the first comprehensive biographical dictionaries, it was intended to serve as a catalyst to stimulate further scholarship.

Could you really use a bullwhip to swing across a chasm? Or rip out a man's heart without killing him? At last, here is the book that finally answers the Indiana Jones-related questions that have troubled you for years. It tells you everything you've ever wanted to know about the history, culture, and science behind your favorite Indy scenes and settings. You'll find out the truth about the Thuggees and their deadly practices, ancient death traps, the Well of Souls, Kali worship in India, and much more.

Advance Praise

"What a treasure house is this book! Robots, space aliens, Einstein, black holes, time travel--these themes, and much more, from Stephen King's amazing books are opened up like toy chests. It's tremendous fun, entirely educational, and a great tribute to King."
--Peter Straub

"A fun, fun read."
--F. Paul Wilson

""The Science of Stephen King" appeals to both the scientist and the longtimereader of Stephen King in me. Gresh and Weinberg use concepts from King's fiction as launching pads for in-depth explorations of concepts as diverse as ESP, pyrokinesis, time travel, artificial intelligence, quantum chemistry, alternate realities, string theory, and the possibility that we'll be visited by aliens or that we'll face a global pandemic. Much of what Stephen King writes about in his novels is closer to reality than you might think."
--Bev Vincent, Ph.D., author of "The Road to the Dark Tower"

"A superb overview of King's use of scientific concepts in his stories. And considering all the scary talk lately about pandemic flu, their chapter on The Stand is timely as hell."
--Stephen Spignesi, author of "The Complete Stephen King Encyclopedia"

"Just as Sagan and Asimov popularized science to the masses by making itentertaining and informative, so too do Gresh and Weinberg.Compulsively readable and thought-provoking."
--George Beahm, author of "The Stephen King Companion"

Tracing the evolving nature of popular and official beliefs about the purported nature of the Jews from the 18th century onwards, Russia and the Jewish Question explores how perceptions of Jews in late Imperial Russia and the Soviet Union shaped the regimes’ policies toward them. In so doing Robert Weinberg provides a fruitful lens through which to investigate the social, economic, political, and cultural developments of modern Russia. Here, Weinberg reveals that the ‘Jewish Question’ – and, by extension anti-Semitism – emerged at the end of the 18th century when the partitions of Poland made hundreds of thousands of Jews subjects of the Russian crown. He skillfully argues the phrase itself implies the singular nature of Jews as a group of people whose religion, culture, and occupational make-up prevent them from fitting into predominantly Christian societies. The book then expounds how other characteristics were associated with the group over time: in particular, debates about rights of citizenship, the impact of industrialization, the emergence of the nation-state, and the proliferation of new political ideologies and movements contributed to the changing nature of the ‘Jewish Question’. Its content may have not remained static, but its purpose consistently questions whether or not Jews pose a threat to the stability and well-being of the societies in which they live and this, in a specifically Russian context, is what Weinberg examines so expertly.

The science behind the gadgets, exploits, and enemies of the world's greatest spy

From the sleek Aston Martin that spits out bullets, nails, and passengers at the push of a button to the microjet that makes hairpin turns to avoid a heat-seeking missile, the science and technology of James Bond films have kept millions of movie fans guessing for decades. Are these amazing feats and gadgets truly possible?

"The Science of James Bond" takes you on a fascinating excursion through the true science that underlies Bond's most fantastic and off-the-wall accoutrements. The acclaimed science-fiction authors Lois Gresh and Robert Weinberg provide a highly entertaining, informative look at the real-world achievements and brilliant imaginations behind such singular Bond gadgets as the buzz-saw Rolex, the car that turns into a submarine, and the ever-popular rocket-firing cigarette. They examine hundreds of Q Division's ingenious inventions; analyze Bond's astonishing battles beneath the earth and sea, in the skies, and even in outer space; and ask intriguing questions that lead to enlightening discussions about the limits of science, the laws of nature, and the future of technology.

Filled with entertaining anecdotes from Bond movie shoots and supplemented with "tech" ratings for all of the Bond movies, "The Science of James Bond" separates scientific fact from film fantasy--with some very surprising results.

The science behind the gadgets, exploits, and enemies of the world's greatest spy

From the sleek Aston Martin that spits out bullets, nails, and passengers at the push of a button to the microjet that makes hairpin turns to avoid a heat-seeking missile, the science and technology of James Bond films have kept millions of movie fans guessing for decades. Are these amazing feats and gadgets truly possible?
The Science of James Bond takes you on a fascinating excursion through the true science that underlies Bond's most fantastic and off-the-wall accoutrements. The acclaimed science-fiction authors Lois Gresh and Robert Weinberg provide a highly entertaining, informative look at the real-world achievements and brilliant imaginations behind such singular Bond gadgets as the buzz-saw Rolex, the car that turns into a submarine, and the ever-popular rocket-firing cigarette. They examine hundreds of Q Division's ingenious inventions; analyze Bond's astonishing battles beneath the earth and sea, in the skies, and even in outer space; and ask intriguing questions that lead to enlightening discussions about the limits of science, the laws of nature, and the future of technology.
Filled with entertaining anecdotes from Bond movie shoots and supplemented with ""tech"" ratings for all of the Bond movies, The Science of James Bond separates scientific fact from film fantasy--with some very surprising results.

Toedliche Armbanduhren, unsichtbare Autos, Atombomben vor Miami: In James Bond Filmen ist schon was geboten. Oft phantastisch, gelegentlich seiner Zeit voraus und manchmal erschreckend realistisch bringen Schurken und Helden die Welt seit 1962 zum Schmunzeln und GrA1/4beln. Was ist dran an den Erfindungen von Q und Konsorten? Welche technischen Spielereien gibt es wirklich, was wA1/4rde passieren, wenn der eine oder andere Schurke seine Plane verwirklichen koennte. Diesen Fragen und vielem mehr gehen Lois H. Gresh und Robert Weinberg nach und geben Ihnen so nicht nur einen A berblick A1/4ber die Bond-Reihe, sondern auch A1/4ber den Stand der Wissenschaft in einigen Gebieten.

"I found this book to be a hoot from beginning to end. Ms. Gresh and Mr. Weinberg must have spent some time in institutions for the deranged, because well-balanced minds could not have conceived of this project. But thank God for their derangement, for they have produced a package of pure fun from first page to last. If, like me, you admire superheroes from a distance, or if you are a hardcore fan of them, you will enjoy this book as surely as you would enjoy waking one morning to discover that you are invincible, able to fly, and in possession of a totally cool costume behind which to hide your true identity." —Dean Koontz, from the Introduction

"We comics fans have known it for years, of course: somewhere, in some nether dimension or on some alternate world, there is an Earth on which superheroes are real, living, breathing beings . . . and now Lois Gresh and Bob Weinberg have shown us how that’s possible. Mutants . . . aliens . . . scientific geniuses with a penchant for wearing costumes and masks . . . or just plain Joes who’ve trained their bodies within an inch of their lives . . . all are probed, dissected, examined in loving details. To paraphrase an old DC Comics feature: Science says you’re wrong if you believe that The Science of Superheroes isn’t more fun than a barrel of genetically-altered winged monkeys." —Roy Thomas, writer and editor of X-Men, Fantastic Four, The Incredible Hulk, Superman, Justice League of America, Legion of Superheroes, Star Wars, and many other comic book classics

"Weinberg and Gresh tell it like it is–– and how it would be, if our favorite comic book characters actually existed. The Science of Superheroes is a fascinating and entertaining examination of everything from astrophysics to genetic biology to the evolution of the "superhero." —Mark Powers, editor of X-Men and Uncanny X-Men

This innovative reassessment of ritual murder accusations brings together scholars working in history, folklore, ethnography, and literature. Favoring dynamic explanations of the mechanisms, evolution, popular appeal, and responses to the blood libel, the essays rigorously engage with the larger social and cultural worlds that made these phenomena possible. In doing so, the book helps to explain why blood libel accusations continued to spread in Europe even after modernization seemingly made them obsolete. Drawing on untapped and unconventional historical sources, the collection explores a range of intriguing topics: popular belief and scientific knowledge; the connections between antisemitism, prejudice, and violence; the rule of law versus the power of rumors; the politics of memory; and humanitarian intervention on a global scale.

This innovative reassessment of ritual murder accusations brings together scholars working in history, folklore, ethnography, and literature. Favoring dynamic explanations of the mechanisms, evolution, popular appeal, and responses to the blood libel, the essays rigorously engage with the larger social and cultural worlds that made these phenomena possible. In doing so, the book helps to explain why blood libel accusations continued to spread in Europe even after modernization seemingly made them obsolete. Drawing on untapped and unconventional historical sources, the collection explores a range of intriguing topics: popular belief and scientific knowledge; the connections between antisemitism, prejudice, and violence; the rule of law versus the power of rumors; the politics of memory; and humanitarian intervention on a global scale.

On Sunday, March 20, 1911, children playing in a cave near Kiev made a gruesome discovery: the blood-soaked body of a partially clad boy. After right-wing groups asserted that the killing was a ritual murder, the police, with no direct evidence, arrested Menachem Mendel Beilis, a 39-year-old Jewish manager at a factory near the site of the crime. Beilis's trial in 1913 quickly became an international cause celebre. The jury ultimately acquitted Beilis but held that the crime had the hallmarks of a ritual murder. Robert Weinberg's account of the Beilis Affair explores the reasons why the tsarist government framed Beilis, shedding light on the excesses of antisemitism in late Imperial Russia. Primary documents culled from the trial transcript, newspaper articles, Beilis's memoirs, and archival sources, many appearing in English for the first time, bring readers face to face with this notorious trial."

On Sunday, March 20, 1911, children playing in a cave near Kiev made a gruesome discovery: the blood-soaked body of a partially clad boy. After right-wing groups asserted that the killing was a ritual murder, the police, with no direct evidence, arrested Menachem Mendel Beilis, a 39-year-old Jewish manager at a factory near the site of the crime. Beilis's trial in 1913 quickly became an international cause celebre. The jury ultimately acquitted Beilis but held that the crime had the hallmarks of a ritual murder. Robert Weinberg's account of the Beilis Affair explores the reasons why the tsarist government framed Beilis, shedding light on the excesses of antisemitism in late Imperial Russia. Primary documents culled from the trial transcript, newspaper articles, Beilis's memoirs, and archival sources, many appearing in English for the first time, bring readers face to face with this notorious trial."

Film music is an increasingly popular part of the classical music repertoire, with a huge range of beautiful, dramatic and well-loved film scores coming out of Hollywood, from Star Wars to Up. From the early days of silent cinema through Hollywood's Golden Age and up to the modern-day blockbusters, this handy reference guide from Classic FM showcases some of the greatest composers of film scores, along with plenty of suggestions for musical delights ready to be discovered. Classical music plays a key role in film soundtracks, creating iconic moments and bringing classic tracks to a wide audience, from 2001: A Space Odyssey to Apocalypse Now. Packed full of essential information, this pocket-sized handbook explores the history of film music, the development of different styles, award-winning composers and the most popular pieces within the genre. Classic FM's Handy Guides are a fun and informative set of introductions to standout subjects within classical music, each of which can be read and digested in one sitting: a perfect collectible series whether you're new to the world of classical music or an aficionado.

A team of experts in each of the ten major Pulp genres, from action Pulps to spicy Pulps and more, chart for the first time the complete history of Pulp magazines-the stories and their writers, the graphics and their artists, and, of course, the publishers, their market, and readers. Each chapter in the book, which is illustrated with more than 400 examples of the best Pulp graphics (many from the Editors' collections-among the world's largest) is organized in a clear and accessible way, starting with an introductory overview of the genre, followed by a selection of the best covers and interior graphics, organized chronologically through the chapter. All images are fully captioned (many are in essence "nutshell" histories in themselves). Two special features in each chapter focus on topics of particular interest (such as extended profiles of Daisy Bacon, Pulp author and editor of Love Story, the hugely successful romance Pulp, and of Harry Steeger, co-founder of Popular Publications in 1930 and originator of the "Shudder Pulp" genre). With an overall Introduction on "The Birth of the Pulps" by Doug Ellis, and with two additional chapters focusing on the great Pulp writers and the great Pulp artists, The Art of the Pulps covers every aspect of this fascinating genre; it is the first definitive visual history of the Pulps.

The third and final volume of our Kaiki series returns us to the Capital City: Tokyo. While Japan has modernized, renaming old Edo as new-born Tokyo, strange secrets remain hidden under the chrome and spotlights, unaffected by our beliefs in Science and Technology. Enjoy a new collection of stories introducing the strange denizens and happenings of the shadowy world of Japanese uncanny literature. Selected and with commentary by Higashi Masao, a recognized researcher and author in the field.

The list of authors includes some of the most famous names in Japanese literature: Akutagawa Ryunosuke, Tanizaki Jun'ichiro, Edogawa Rampo, Hisao Juran, Endo Shusaku, Kawabata Yasunari and others.

Volume 2 of a 3-volume series covering the evolution and scope of Japanese "kaiki" fiction: uncanny tales, including ghost stories, weird tales and subtle horror. Translations by experts in the field bring an entirely new genre of literature to the English language. The stories are accompanied by one manga, and a comprehensive introduction to the development of the genre in Japan by Higashi Masao, the foremost authority in the field.

Japan has a long history of weird and supernatural literature, but it has been introduced into English only haphazardly until now. The first volume of a 3-volume anthology covering over two centuries of kaiki literature, including both short stories and manga, from Ueda Akinari's Ugetsu Monogatari of 1776 to Kyogoku Natsuhiko's modern interpretations of popular tales. Selected and with commentary by Higashi Masao, a recognized researcher and author in the field, the series systemizes and introduces the scope of the field and helps establish it as a genre of its own. This first volume presents a variety of work focusing on pre-modern Japan, and includes one manga.

Revolutionary Russia: A History in Documents provides a visually stimulating survey of revolutionary Russia, from the collapse of the autocracy in 1917 to the consolidation of the Stalinist system in the 1930s. Authors Robert Weinberg and Laurie Bernstein have collected far-flung documents--many available in English for the first time--and woven them into a narrative that focuses on the effort to build communism in Russia and its effects on the lives of ordinary people. Providing introductions to each chapter and document along with sidebars and detailed photo captions, the main text tantalizes readers with the great vision, conflict, hopes, and horrors of this much-mythologized part of modern history, while the back matter offers resources for further exploration.
Utilizing a mix of textual and visual documents-including photographs, posters, and objects-to create a textured history of revolutionary Russia, the book covers such diverse topics as the prelude to revolution, the Bolshevik rise to power, the fate of the royal family, peasant resistance to Bolshevik policies, Stalin's "revolution from above," and the Great Terror. A picture essay, featuring sixteen posters, provides a visual depiction of the impact of the revolution on women.