This book constitutes the refereed proceedings of the Second International Bioinformatics, WABI 2002, held in Rome, Italy, in September 2002.The 39 revised full papers presented together with an full invited paper were carefully reviewed and selected from 83 submissions. Among the topics addressed are exact and approximate algorithms for genomics, genetics, sequence analysis, gene and signal recognition, alignment, molecular evolution, phylogenetics, structure determination and prediction, gene expression and gene networks, proteomics, functional genomics, and drug design.

Articles in EGASP '05 are based on presentations made at the E-GASP 2005 gene prediction workshop, held in Hinxton, UK, on 6-7 May 2005. The workshop was community experiment to assess the state-of-the-art in genome annotation in the human genome, with the goal of assessing the accuracy of computational methods to predict protein coding genes in DNA and the overall assessment of the completeness of the current human genome annotations.