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This volume of The Enzymes features high-caliber thematic articles
on the topic of molecular machines involved in protein transport
across cellular membranes. The book consists of five parts which
span the range of membranes including bacterial, endoplasmic
reticulum, mitochondrial, chloroplast, and peroxismal.
This book presents an in-depth overview on the topic of protein
synthesis, covering all areas of protein science, including protein
targeting, secretion, folding, assembly, structure, localization,
quality control, degradation, and antigen presentation. Chapters
also include sections on the history of the field as well as
summary panels for quick reference. Numerous color illustrations
complement the presentation of material. This book is an essential
reference for anyone in biochemistry and protein science, as well
as an excellent textbook for advanced students in these and related
fields.
Key Features
* Basic principles and techniques
* Targeting adn sorting sequences
* Protein export in bacteria
* Membrane protein integration into ER and bacterial
membranes
* Protein translocation across the ER
* Disulfide bond formation in prokaryotes and eukaryotes
* Quality control in the export pathway
* Import of proteins into organelles
* The secretory pathway
* Vesicular transport
* Spectacular color throughout
This volume examines a number of different proteases, a type of
enzyme, that are required in order for the change to a biologically
active mature protein to occur. The discussion of these various
proteases is rarely undertaken in one volume and will serve as a
great resource for scientists studying the group of proteases on
signal peptide processing as well as those working on propeptide
processing. These areas of research do not normally overlap, and
yet they are each of common importance to the same cell processes.
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