Use of psychotropic drugs has come to dominate clinical practice in psychiatry worldwide-perhaps owing largely to perceived simplicity, ease of use, and apparent efficiency, as well as apparent cost-effectiveness of such treatments. Nevertheless, medicinal treatments for patients with psychiatric disorders are but one component of comprehensive clinical care of complex human problems. Extensively updated since its second edition in 1985, "Chemotherapy in Psychiatry," "Third Edition, " again addresses basic aspects of modern psychopharmacology and clinical applications of drugs used in the treatment of major psychiatric disorders, with major emphasis on psychotic, bipolar, and depressive disorders. The presentation covers descriptions of the main classes of psychotropic drugs, selected information concerning their known action mechanisms and metabolic disposition, and their clinical applications for acute illnesses and to prevent recurrences and long-term morbidity. Also covered are limitations and adverse effects of each type of agent, with emphasis on the fact that all psychotropic medicines have adverse effects that range from annoying to potentially lethal." Chemotherapy in Psychiatry, Third Edition, " outlines the need to balance benefits and risks at the level of individual persons. Authoritative, and an important contribution to the literature, "Chemotherapy in Psychiatry, Third Edition" is an invaluable resource for physicians, scientists, trainees, and policymakers. "

Use of psychotropic drugs has come to dominate clinical practice in psychiatry worldwide-perhaps owing largely to perceived simplicity, ease of use, and apparent efficiency, as well as apparent cost-effectiveness of such treatments. Nevertheless, medicinal treatments for patients with psychiatric disorders are but one component of comprehensive clinical care of complex human problems. Extensively updated since its second edition in 1985, Chemotherapy in Psychiatry, Third Edition, again addresses basic aspects of modern psychopharmacology and clinical applications of drugs used in the treatment of major psychiatric disorders, with major emphasis on psychotic, bipolar, and depressive disorders. The presentation covers descriptions of the main classes of psychotropic drugs, selected information concerning their known action mechanisms and metabolic disposition, and their clinical applications for acute illnesses and to prevent recurrences and long-term morbidity. Also covered are limitations and adverse effects of each type of agent, with emphasis on the fact that all psychotropic medicines have adverse effects that range from annoying to potentially lethal. Chemotherapy in Psychiatry, Third Edition, outlines the need to balance benefits and risks at the level of individual persons. Authoritative, and an important contribution to the literature, Chemotherapy in Psychiatry, Third Edition is an invaluable resource for physicians, scientists, trainees, and policymakers.

The advent of chemical or pharmacological therapies has had an enormous impact on the treatment of psychiatric illness. For the chemotherapy to be effective, however, the clinician must take into account many factors in addition to recognition of a syndrome and selection of an appropriate agent and dose. In this extensively revised and expanded edition of a widely used book, Ross Baldessarini concentrates on providing rational, scientific underpinnings for the treatment of patients. In doing so, he bridges the gap between biology, psychology, and clinical practice.

To provide the most up-to-date coverage of the actions and use of psychotropic agents, Professor Baldessarini has enlarged the text to nearly twice its original length and has added sixty-three new tables. More basic preclinical pharmacology is included to guide the thoughtful use of medication. In addition to summarizing this basic knowledge, the text reviews the indications for each drug, the kinds of patients most likely to respond, and side effects and contraindications, and provides summaries of clinical research findings on which rational clinical practice rests.

A chapter is devoted to each of the principal classes of psychotropic drugs: antipsychotic agents, lithium salts and other antimanic agents, antidepressant agents, and antianxiety drugs. Within each chapter is a new section that surveys the future of the field and examines new procedures, theories, and agents. A final chapter covers more general topics such as psychosocial, ethical, and legal aspects of practice in the administration of drugs, as well as the emerging topics of geriatric and pediatric psychopharmacology--material not readilyavailable elsewhere.