By selecting the ?rst week of June 2008 for the Nobel Symposium "Single Molecular Spectroscopy in Chemistry, Physics and Biology", Rudolf Rigler, Jerker Widengren and Astrid Grasl .. und have once again won the top prize for Meeting Organizers, providing us with a Mediterranean climate on top of the warm hospitality that is unique to Sweden. The S? anga Sab .. y Conference Center was an ideal place to spend this wonderful week, and the comfort of this beautiful place blended perfectly with the high calibre of the scienti?c programme. It was a special privilege for me to be able to actively participate in this meeting on a ?eld that is in many important ways complementary to myownresearch. Iwasimpressedbytheinterdisciplinarywaysinwhichsingle molecule spectroscopy has evolved and is currently pursued, with ingredients originating from physics, all branches of chemistry and a wide range of b- logical and biomedical research. A beautiful concert by Semmy Stahlhammer and Johan Ull' en further extended the interdisciplinary character of the s- posium. I would like to combine thanks to Rudolf, Jerker and Astrid with a glance into a future of other opportunities to enjoy top-levelscience combined with warm hospitality in the Swedish tradition. Z.. urich, Kurt Wuth .. rich April 2009 Participants of the Nobel-Symposium 138: First row: Sarah Unterko?er, Anders Liljas, Xiao-Dong Su, Birgitta Rigler, Carlos Bus- mante, Toshio Yanagida, Steven Block, Xiaowei Zhuang, Sunney Xie. Second row: Ivan Scheblykin, Lars Thelander, Petra Schwille, Watt W.

This is a collection of papers presented and discussed at the first EBSA workshop held at Saltsj6baden outside stockholm in Sweden, July 6-10, 1986. The common theme of these papers is dynamics of biomolecules, and how the dynamics depends on the molecular structure and organi zation, and connects to and determines the biological function. This is a rapidly expanding field of research which combines many different aspects of molecular bio physics. Much material is new and presented for the first time. Even if the work so far has been of the kind that is usually called basic research, practical applications are clearly indicated in some articles, and are waiting around the corner in several other cases. At the workshop only one third of the time was used for the formal presentations and two thirds for discussion. To this should also be added discussions during the poster sessions. During these lively and unrecorded discussions fresh viewpoints emerged and new ideas were created. Ad mittedly, our knowledge at present is only fragmentary but when pieces of the puzzle are brought together at a workshop or in a publication of this kind more extended and sometimes unexpected contours and shapes become vi sible. It is our hope that this rapid publication of camera-ready manuscripts will transfer some of the spi rit at the workshop to the reader, and in his or her institute or laboratory initiate further discussions, bring forward more ideas and start new experimental ap roaches."

By selecting the ?rst week of June 2008 for the Nobel Symposium "Single Molecular Spectroscopy in Chemistry, Physics and Biology", Rudolf Rigler, Jerker Widengren and Astrid Grasl .. und have once again won the top prize for Meeting Organizers, providing us with a Mediterranean climate on top of the warm hospitality that is unique to Sweden. The S? anga Sab .. y Conference Center was an ideal place to spend this wonderful week, and the comfort of this beautiful place blended perfectly with the high calibre of the scienti?c programme. It was a special privilege for me to be able to actively participate in this meeting on a ?eld that is in many important ways complementary to myownresearch. Iwasimpressedbytheinterdisciplinarywaysinwhichsingle molecule spectroscopy has evolved and is currently pursued, with ingredients originating from physics, all branches of chemistry and a wide range of b- logical and biomedical research. A beautiful concert by Semmy Stahlhammer and Johan Ull' en further extended the interdisciplinary character of the s- posium. I would like to combine thanks to Rudolf, Jerker and Astrid with a glance into a future of other opportunities to enjoy top-levelscience combined with warm hospitality in the Swedish tradition. Z.. urich, Kurt Wuth .. rich April 2009 Participants of the Nobel-Symposium 138: First row: Sarah Unterko?er, Anders Liljas, Xiao-Dong Su, Birgitta Rigler, Carlos Bus- mante, Toshio Yanagida, Steven Block, Xiaowei Zhuang, Sunney Xie. Second row: Ivan Scheblykin, Lars Thelander, Petra Schwille, Watt W.

This book focuses on recent advances in the rapidly evolving field of single molecule research. These advances are of importance for the investigation of biopolymers and cellular biochemical reactions, and are essential to the development of quantitative biology. Written by leading experts in the field, the articles cover a broad range of topics, including quantum photonics of organic dyes and inorganic nanoparticles and monitoring of single molecule (enzymatic) reactions.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfangen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen fur die historische wie auch die disziplingeschichtliche Forschung zur Verfugung, die jeweils im historischen Kontext betrachtet werden mussen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

This book surveys recent advances related to the application of single molecule techniques in various fields of science. The topics, each described by leading experts in the field, range from single molecule experiments in quantum optics and solid-state physics to analogous investigations in physical chemistry and biophysics. A unifying theme of all chapters is the power of single molecule techniques to unravel fluctuations and heterogeneities usually hidden in the ensemble average of complex systems. The concept for the book originated from a gathering of some of the world's leading scientists at the Nobel Conference in Sweden.