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Often considered the workhorse of the cellular machinery, proteins
are responsible for functions ranging from molecular motors to
signaling. The broad recognition of their involvement in all
cellular processes has led to focused efforts to predict their
functions from sequences, and if available, from their structures.
An overview of current research directions, Computational
Protein-Protein Interactions examines topics in the prediction of
protein-protein interactions, including interference with
protein-protein interactions and their design. Explores
Computational Approaches to Understanding Protein-Protein
Interactions Outlining fundamental and applied aspects of the
usefulness of computations when approaching protein-protein
interactions, this book incorporates different views of the same
biochemical problem from sequence to structure to energetics. It
covers protein-protein interaction prediction and dynamics, design,
drug design for inhibition, and uses for the prediction of
function. The text provides general chapters that overview the
topic and also includes advanced material. The chapters detail the
complexity of protein interaction studies and discuss potential
caveats. Addresses the Next Big Problem in Molecular Biology While
it is important to predict protein associations, this is a daunting
task. Edited by two experts in the field and containing
contributions from those at the forefront of research, the book
provides a basic outline of major directions in computational
protein-protein interactions research at the heart of functional
genomics and crucial for drug discovery. It addresses the next big
problem in molecular biology: how to create links between all the
pieces of the cell jigsaw puzzle.
Often considered the workhorse of the cellular machinery, proteins
are responsible for functions ranging from molecular motors to
signaling. The broad recognition of their involvement in all
cellular processes has led to focused efforts to predict their
functions from sequences, and if available, from their structures.
An overview of current research directions, Computational
Protein-Protein Interactions examines topics in the prediction of
protein-protein interactions, including interference with
protein-protein interactions and their design. Explores
Computational Approaches to Understanding Protein-Protein
Interactions Outlining fundamental and applied aspects of the
usefulness of computations when approaching protein-protein
interactions, this book incorporates different views of the same
biochemical problem from sequence to structure to energetics. It
covers protein-protein interaction prediction and dynamics, design,
drug design for inhibition, and uses for the prediction of
function. The text provides general chapters that overview the
topic and also includes advanced material. The chapters detail the
complexity of protein interaction studies and discuss potential
caveats. Addresses the Next Big Problem in Molecular Biology While
it is important to predict protein associations, this is a daunting
task. Edited by two experts in the field and containing
contributions from those at the forefront of research, the book
provides a basic outline of major directions in computational
protein-protein interactions research at the heart of functional
genomics and crucial for drug discovery. It addresses the next big
problem in molecular biology: how to create links between all the
pieces of the cell jigsaw puzzle.
As one of the fastest growing fields of research in the 21st
century, nanotechnology is sure to have an enormous impact on many
aspects of our lives. Nanostructure Design: Methods and Protocols
serves as a major reference for theoretical and experimental
considerations in the design of biological and bio-inspired
building blocks, the physical characterization of the formed
structures, and the development of their technical applications.
The chapters contributed by leading experts are divided into two
sections, the first of which covers experimental aspects of
nanostructure design and the second delves into computational
methods. As a volume of the highly successful Methods in Molecular
Biology (TM) series, this collection pulls together cutting-edge
protocols, written in a step-by-step, readily reproducible format
certain to guide researchers to the desired results. Comprehensive
and essential, Nanostructure Design: Methods and Protocols uses
biological principles and vehicles on design to aid scientists in
the great challenges still ahead.
As one of the fastest growing fields of research in the 21st
century, nanotechnology is sure to have an enormous impact on many
aspects of our lives. Nanostructure Design: Methods and Protocols
serves as a major reference for theoretical and experimental
considerations in the design of biological and bio-inspired
building blocks, the physical characterization of the formed
structures, and the development of their technical applications.
The chapters contributed by leading experts are divided into two
sections, the first of which covers experimental aspects of
nanostructure design and the second delves into computational
methods. As a volume of the highly successful Methods in Molecular
Biology (TM) series, this collection pulls together cutting-edge
protocols, written in a step-by-step, readily reproducible format
certain to guide researchers to the desired results. Comprehensive
and essential, Nanostructure Design: Methods and Protocols uses
biological principles and vehicles on design to aid scientists in
the great challenges still ahead.
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