Drama based on the teenage years of writer and director Lori Petty. Agnes (Jennifer Lawrence) is the oldest of three daughters who finds herself caring for her younger siblings when her single mother (Selma Blair) turns to prostitution, drugs and alcohol after meeting a pimp named Duval (Bokeem Woodbine), who seems to have a fondness for Agnes. With their house overrun by gamblers, criminals and other seedy characters the girls struggle to lead a normal life. Cammie (Chloë Grace Moretz) escapes the chaos of the house only to sit in bars and Bee (Sophi Bairley) wants nothing more than to run away and be adopted, while Agnes tries to earn enough money to support her family and manage the expectations of being a star basketball player.

Another feature-length adventure following the Mystery Incorporated team. This time the gang investigate at the Mega Mondo Pop Cartoon-a-Con where the villainous Mr. Hyde (voice of John DiMaggio) releases a horde of evil creatures. Shaggy (Matthew Lillard) and Scooby (Frank Welker) take inspiration from their favourite superheroes Blue Falcon and Dynomutt as they attempt to put a stop to Mr. Hyde's wicked ways and save the convention.

The prospect of entering treatment is overwhelming for anyone facing a diagnosis of cancer. While patients have access to a vast amount of medical information online, this advice is often unreliable or confusing. In Living with Cancer, Drs. Vicki A. Jackson and David P. Ryan have crafted the first step-by-step guide aimed at helping people with this life-defining disease grasp what's happening to them while coping physically and emotionally with cancer treatment. An empathetic resource full of relatable patient stories, this book teaches patients and caregivers how to ask the right questions to get the best possible care-beginning at the moment of diagnosis. Drs. Jackson and Ryan explain how to work with a team of doctors and nurse practitioners to minimize symptoms and side effects while living as fully as possible in the face of cancer. They relay important information about understanding prognosis, and they translate what doctors mean when they describe tests, treatments, and medical procedures. Finally, they discuss hospice care and answer questions about continuing treatment and managing the final phase of life. Based on new research and a groundbreaking program in which patients are treated with palliative care-along with the best cancer care-during the course of their illness, this honest and caring book provides the right advice to use at the right time throughout a journey with cancer. It allows a person with cancer to concentrate on living the best life possible, despite an uncertain future. Patients at every stage will find Living with Cancer a comprehensive, thoughtful, and accessible guide for navigating the illness and its treatment.

The prospect of entering treatment is overwhelming for anyone facing a diagnosis of cancer. While patients have access to a vast amount of medical information online, this advice is often unreliable or confusing. In Living with Cancer, Drs. Vicki A. Jackson and David P. Ryan have crafted the first step-by-step guide aimed at helping people with this life-defining disease grasp what's happening to them while coping physically and emotionally with cancer treatment. An empathetic resource full of relatable patient stories, this book teaches patients and caregivers how to ask the right questions to get the best possible care-beginning at the moment of diagnosis. Drs. Jackson and Ryan explain how to work with a team of doctors and nurse practitioners to minimize symptoms and side effects while living as fully as possible in the face of cancer. They relay important information about understanding prognosis, and they translate what doctors mean when they describe tests, treatments, and medical procedures. Finally, they discuss hospice care and answer questions about continuing treatment and managing the final phase of life. Based on new research and a groundbreaking program in which patients are treated with palliative care-along with the best cancer care-during the course of their illness, this honest and caring book provides the right advice to use at the right time throughout a journey with cancer. It allows a person with cancer to concentrate on living the best life possible, despite an uncertain future. Patients at every stage will find Living with Cancer a comprehensive, thoughtful, and accessible guide for navigating the illness and its treatment.

This handbook offers a comprehensive treatise on Grammatical Evolution (GE), a grammar-based Evolutionary Algorithm that employs a function to map binary strings into higher-level structures such as programs. GE's simplicity and modular nature make it a very flexible tool. Since its introduction almost twenty years ago, researchers have applied it to a vast range of problem domains, including financial modelling, parallel programming and genetics. Similarly, much work has been conducted to exploit and understand the nature of its mapping scheme, triggering additional research on everything from different grammars to alternative mappers to initialization. The book first introduces GE to the novice, providing a thorough description of GE along with historical key advances. Two sections follow, each composed of chapters from international leading researchers in the field. The first section concentrates on analysis of GE and its operation, giving valuable insight into set up and deployment. The second section consists of seven chapters describing radically different applications of GE. The contributions in this volume are beneficial to both novices and experts alike, as they detail the results and researcher experiences of applying GE to large scale and difficult problems. Topics include: * Grammar design * Bias in GE * Mapping in GE * Theory of disruption in GE * Structured GE * Geometric semantic GE * GE and semantics * Multi- and Many-core heterogeneous parallel GE * Comparing methods to creating constants in GE * Financial modelling with GE * Synthesis of parallel programs on multi-cores * Design, architecture and engineering with GE * Computational creativity and GE * GE in the prediction of glucose for diabetes * GE approaches to bioinformatics and system genomics * GE with coevolutionary algorithms in cybersecurity * Evolving behaviour trees with GE for platform games * Business analytics and GE for the prediction of patient recruitment in multicentre clinical trials

This book covers the normal anatomy of the human body as seen in the entire gamut of medical imaging. It does so by an initial traditional anatomical description of each organ or system followed by the radiological anatomy of that part of the body using all the relevant imaging modalities. The third edition addresses the anatomy of new imaging techniques including three-dimensional CT, cardiac CT, and CT and MR angiography as well as the anatomy of therapeutic interventional radiological techniques guided by fluoroscopy, ultrasound, CT and MR. The text has been completely revised and over 140 new images, including some in colour, have been added. A series of 'imaging pearls' have been included with most sections to emphasise clinically and radiologically important points. The book is primarily aimed at those training in radiology and preparing for the FRCR examinations, but will be of use to all radiologists and radiographers both in training and in practice, and to medical students, physicians and surgeons and all who use imaging as a vital part of patient care. The third edition brings the basics of radiological anatomy to a new generation of radiologists in an ever-changing world of imaging. This book covers the normal anatomy of the human body as seen in the entire gamut of medical imaging. It does so by an initial traditional anatomical description of each organ or system followed by the radiological anatomy of that part of the body using all the relevant imaging modalities. The third edition addresses the anatomy of new imaging techniques including three-dimensional CT, cardiac CT, and CT and MR angiography as well as the anatomy of therapeutic interventional radiological techniques guided by fluoroscopy, ultrasound, CT and MR. The text has been completely revised and over 140 new images, including some in colour, have been added. A series of 'imaging pearls' have been included with most sections to emphasise clinically and radiologically important points. The book is primarily aimed at those training in radiology, but will be of use to all radiologists and radiographers both in training and in practice, and to medical students, physicians and surgeons and all who use imaging as a vital part of patient care. The third edition brings the basics of radiological anatomy to a new generation of radiologists in an ever-changing world of imaging. Anatomy of new radiological techniques and anatomy relevant to new staging or treatment regimens is emphasised. 'Imaging Pearls' that emphasise clinically and radiologically important points have been added throughout. The text has been revised to reflect advances in imaging since previous edition. Over 100 additional images have been added.

This handbook offers a comprehensive treatise on Grammatical Evolution (GE), a grammar-based Evolutionary Algorithm that employs a function to map binary strings into higher-level structures such as programs. GE's simplicity and modular nature make it a very flexible tool. Since its introduction almost twenty years ago, researchers have applied it to a vast range of problem domains, including financial modelling, parallel programming and genetics. Similarly, much work has been conducted to exploit and understand the nature of its mapping scheme, triggering additional research on everything from different grammars to alternative mappers to initialization. The book first introduces GE to the novice, providing a thorough description of GE along with historical key advances. Two sections follow, each composed of chapters from international leading researchers in the field. The first section concentrates on analysis of GE and its operation, giving valuable insight into set up and deployment. The second section consists of seven chapters describing radically different applications of GE. The contributions in this volume are beneficial to both novices and experts alike, as they detail the results and researcher experiences of applying GE to large scale and difficult problems. Topics include: * Grammar design * Bias in GE * Mapping in GE * Theory of disruption in GE * Structured GE * Geometric semantic GE * GE and semantics * Multi- and Many-core heterogeneous parallel GE * Comparing methods to creating constants in GE * Financial modelling with GE * Synthesis of parallel programs on multi-cores * Design, architecture and engineering with GE * Computational creativity and GE * GE in the prediction of glucose for diabetes * GE approaches to bioinformatics and system genomics * GE with coevolutionary algorithms in cybersecurity * Evolving behaviour trees with GE for platform games * Business analytics and GE for the prediction of patient recruitment in multicentre clinical trials