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From its beginning as a state, New Hampshire provided for the poor
and unfortunate who resided in its towns. Individual towns had
systems in place for dealing with the fate of indigent persons:
support, punishment or removal. Major towns and cities had an
official Overseer of the Poor who either resided at the poor farm
or who arranged for the lodging and care of town paupers. County
and city poor farms had been established throughout New Hampshire
by the mid-1800s. In 1883, the state began to require a standard
affidavit which covered the person's age, place of birth, the times
and places of residence, plus times and places where support had
been previously received. This book presents a transcription of a
clerk's notebook from Keene, New Hampshire, which recorded
interviews held for those who came seeking assistance from Cheshire
County between 1885 and 1900. Entries typically contain:
applicant's name, present residence, age, place of birth, places
lived, and sometimes the circumstances that led to the need to ask
for help, the date of the application, and when the case was
adjudged. Three indices augment the records: a subject index for
frequently mentioned topics, a place name index, and a full name
index. A woman may be listed twice in the full name index if both a
maiden name and a married name are recorded.
Many crimes were not reported in New Hampshire's local newspapers
throughout the 1812-1883 period. This might lead researchers to
believe that this period was relatively crime-free; however, the
lack of coverage was due to the newspaper's space limitation
Written for biologists and medical researchers who don't have any
special training in data analysis and statistics, Guide to Analysis
of DNA Microarray Data, Second Edition begins where DNA array
equipment leaves off: the image produced by the microarray. The
text deals with the questions that arise starting at this point,
providing an introduction to microarray technology, then moving on
to image analysis, data analysis, cluster analysis, and
beyond.
With all chapters rewritten, updated, and expanded to include the
latest generation of technology and methods, Guide to Analysis of
DNA Microarray Data, Second Edition offers practitioners reliable
information using concrete examples and a clear, comprehensible
style. This Second Edition features entirely new chapters on:
* Image analysis
* Experiment design
* Automated analysis, integrated analysis, and systems
biology
* Interpretation of results
Intended for readers seeking practical applications, this text
covers a broad spectrum of proven approaches in this rapidly
growing technology. Additional features include further reading
suggestions for each chapter, as well as a thorough review of
available analysis software.
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