The crude methanolic extract and different fractions of plant Boerhavia repens were subjected to a number of biological tests for the evaluation of their pharmacological activity.The whole plant of Boerhavia repens was extracted with methanol by cold extraction method. The concentrated extract of the plant were then partitioned into pet ether, carbon tetrachloride, dichloromethane and ethyl acetate soluble fractions.The carbon tetrachloride, dichloromethane and the ethyl acetate soluble fractions of the plant showed strong anti-oxidant activity. The cytotoxicity evaluation of the plant extracts were carried out by Brine Shrimp Lethality Bioassay. The pet ether soluble fractions of the plant showed strong cytotoxic activity. The crude methanolic extract and pet ether soluble fraction at doses of 400 mg/kg exhibited strong analgesic activity, anti-inflammatory and anti-pyretic activity. The different fractions and the crude methanolic extract were also subjected to anti-microbial assay. However no fractions exhibited strong anti-microbial activity.

Medicinal plants are important source to be explored for the discovery and development of newer, safer and effective drug candidates. In medicinal plants research, bioactivity guided phytochemical research can be considered as a rational approach. The ethanopharmacological investigations of the study plant Schoenoplectus grossus was carried out for the first time ever in research lab by Professor Dr. Rahman's research group. The powdered root of this plant was extracted with methanol and fractioned by modified Kupchan partitioning method to provide petroleum ether, carbon tetrachloride, dichloromethane, and ethyl acetate soluble fractions. All fractions and methanol extract were investigated for pharmacological activities on animal model. The analgesic, antipyretic, anti-inflammatory, antihelmintic, and antidiarrheal effects were analyzed on dose dependent manner by comparing with standard reference drug. The extract was also screened out for cytotoxic, antioxidant, and thrombolytic activity by in vitro methods.