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This is a comprehensive, state-of-the-art guide to the diagnosis,
treatment, and biology of multiple myeloma and related plasma
disorders. Edited and written by a multidisciplinary group of
recognized authorities from the Mayo Clinic, it presents clear
guidelines on diagnosis and therapy and covers all aspects of
multiple myeloma, from molecular classification and diagnosis, to
risk stratification and therapy. Closely related plasma cell
disorders such as solitary plasmacytoma, Waldenstrom
macroglobulinemia, and light chain amyloidosis are discussed in
detail as well. The book addresses often overlooked topics,
including the role of radiation therapy, vertebral augmentation,
and supportive care. Our understanding of this group of disorders
is developing at an unprecedented rate, and Multiple Myeloma meets
the need among oncologists and hematologists for a clear, timely,
and authoritative resource on their biology, diagnosis, and
treatment.
Due to major advances in understanding the biology and pathogenesis
of the disease, the management of multiple myeloma is changing
rapidly. New diagnostic and prognostic criteria have been
introduced, and treatment options are multiplying with high-dose
chemotherapy regimens, stem cell transplants, and the development
of novel agents and immune-based strategies that target tumor cells
directly. This book is aimed at the practitioner who is looking to
put these advances into clinical context. It will serve as an
up-to-date resource for treatment of myeloma and related disorders.
Chapters are written by international authorities and contain color
photos, diagrams, and algorithms outlining preferred treatment
strategies. Relevant scientific information is integrated
throughout, but the focus here is on providing practical
therapeutic guidance for oncologists and hematologists caring for
myeloma patients. The book covers all myeloma subtypes and related
disorders, including amyloidosis, Waldenstrom macroglobulinemia,
plasmacytoma, MGUS, and POEMS syndrome.
This is a reproduction of a book published before 1923. This book
may have occasional imperfections such as missing or blurred pages,
poor pictures, errant marks, etc. that were either part of the
original artifact, or were introduced by the scanning process. We
believe this work is culturally important, and despite the
imperfections, have elected to bring it back into print as part of
our continuing commitment to the preservation of printed works
worldwide. We appreciate your understanding of the imperfections in
the preservation process, and hope you enjoy this valuable book.
Genetics is the science of heredity that involves the study of
structure and function of genes. Applied genetics refers to the
study of the involvement of the structure and function of genes in
various practical fields. This book provides a focused introduction
to the basic genetic principles and presents the molecular aspects
and latest applied areas in genetics in considerable detail. The
simple and lucid presentation of complicated topics in basic
genetics, molecular genetics, medical genetics and in the latest
applied areas of genetics would prove to be very useful to
students, researchers and teachers.
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