In recent years, the use of inorganic antimicrobial agents has attracted interest because of their industrial and medical applications. The important advantages of antimicrobial inorganic agents are improved safety and stability. Titanium complexes are known to show variety of applications. These include role of titanium coatings in infection control in the healthcare sector, the food industry and in aviation. In order to get them accepted, it will be necessary to show activity against relevant pathogens and under conditions found in those industries.SBA 16 material has excellent potential for application in environmental area due to the control both the size and the shape of the pores in the structure of this material, although it has been little exploited. This study concluded that Ti SBA-16-type mesoporous material has maximum antibacterial activity against E. coli, then against S. aureus and then B. subtilis.