Multiple sclerosis is the most common debilitating neurological disease in people under the age of forty in the developed world. Many publications cover medical and clinical approaches to the disease; however, The Biology of Multiple Sclerosis provides a clear and concise up-to-date overview of the scientific literature on the various theories of MS pathogenesis. Covering the main elements of scientific research into multiple sclerosis, the book contains chapters on the neuropathology of the disease as well as an account of the most extensively used animal model experimental autoimmune encephalomyelitis. The book contains chapters regarding the role of viruses in the development of multiple sclerosis. Viruses have long been implicated and chapters on animal models based on virus infection, as well as their possible role in the etiology of MS, are included. Of interest to MS researchers, the book is written to also be of value to postgraduate and medical students.

Multiple Sclerosis (MS) is thought to affect almost 2.5 million people worldwide. With the arrival of several new MS drugs and increased availability of information on the internet, many people are confronted by an overwhelming number of information sources about how best to manage their condition. This new book explains, in a clear and accessible way, what is currently known about MS. It provides an explanation of the disease process, symptoms, diagnosis, and how drugs and alternative approaches to disease management work. It also provides supplementary information on how lifestyle and diet changes may help.
Multiple Sclerosis: The Facts addresses the most frequently asked questions about MS, and provides answers in an easy-to-read and accessible format. The book is an invaluable resource for people with MS, and their families and health care workers will also find it a go-to guide to help understand the disease more clearly. This book will also be of interest to medical students and MS researchers.

The brain is often thought of as an immune-privilege site, implying that trafficking of immune cells and molecules into the central nervous system is limited or controlled so as to prevent collateral damage. Nevertheless, there is increasing evidence demonstrating complex interactions between the immune system and the nervous systems. The increasing evidence for the role of auto-immunity to neuronal proteins in both peripheral and central nervous system disorders has led to the development of animal models and in vitro systems to probe human disorders. This book reviews evidence for auto-immunity to neurons and axons in neurological diseases, discusses the animal models that are used to study the mechanisms of disease and indicates how such auto-immunity is relevant for therapies in these disorders.