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"The Adventures of Annie and Ellie" is a series of stories written
for young children to help instill Scriptural and moral values in
their lives while they are young so that it becomes a part of their
everyday choices as they mature.
Just imagine that people suddenly lost most of their money and
Santa Claus told children that he would no longer be sending
presents. Wouldn't the world be a miserable place? When Father
Christmas Resigned is the story of how one young girl's
determination to help a man in need leads to new hope for children
and their parents everywhere.
This is the ultimate novel of self-discovery and self-love for
those who are coming out of hibernation and ready to do some
emotional spring cleaning, or for those who are simply looking for
a renewed spirit.
Myotonic dystrophy is a multisystemic disorder. The epidemiology of
DM is examined in the first chapter of this book as well as
potential therapeutic strategies. The authors then go on to review
the various involvement of the endocrine system in myotonic
dystrophy and therapeutic strategies are proposed. The fourth
chapter gives an overview on the diagnostic assessment and
management of distinct clinical manifestations of CNS (Central
Nervous System) involvement in DM patients, and the main topics
regarding its pathogenesis are explored. The next chapter focuses
on the strategy of neuromuscular blockage for patients with
myotonic dystrophy, especially focusing on premedication, induction
of anaesthesia, response to muscle relaxants, the crucial points of
safe anaesthesiological care and other perioperative triggers. The
development of biomarkers is of high importance in the diagnosis
and monitoring of diseases and thus is examined with relation to
DM1 (myotonic dystrophy type 1) patients. Other chapters summarize
the different rehabilitative approaches that have been proposed in
this disease; the novel, interesting findings of therapeutic
potential to target DM1 with small molecule kinase inhibitors and
the promises his may provide to this devastating disorder; the
controversial, phenotypical consequences of the interrupted alleles
on DM1 patients; and the sleep disorders associated with myotonic
dystrophies.
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