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This thoroughly revised second edition is an up-to-date overview of
the current knowledge of Notch and Notch signaling in embryology
and cancer. It discusses this topic from Notch's role in the
development of the embryo to the Notch signaling pathway's role in
the development of a number of cancers, including breast cancer,
malignant melanoma, Non-melanoma skin cancer, intestinal cancer and
others. In the years since the previous edition, there have been
numerous developments and insights within this rapidly moving
field, making this new edition urgently needed. This volume also
features discussions of current insights on Notch's role in
senescence, the regulation of Notch signaling by microRNAs, Notch's
role in the microbiome, diet and its influence on Notch signaling
and more. Taken as a whole, with its companion books -- Notch
Signaling and Embryologic Development and Molecular Basis of Notch
Signaling - this is a definitive discussion of the topic, presented
by internationally-recognized contributors. Presented in a coherent
and accessible structure, this revised and updated second edition
is an essential and up-to-date guide for oncologists,
embryologists, researchers and advanced students.
This thoroughly revised second edition is an up-to-date overview of
the current knowledge of Notch and Notch signaling in embryology
and cancer. It summarizes the newest achievements on this topic
from Notch's flag-ship function in the development of the embryo
and for various inherited diseases to the Notch signaling pathway's
role in the development of leukemia and in a number of cancers,
including skin cancer, intestinal cancer and others. Additionally,
the emerging new role of the Notch signaling pathway as a promising
target for prevention and therapy of various diseases, including
cancer, is discussed. In the years since the previous edition,
there have been numerous developments and insights within this
rapidly moving field, making this new edition urgently needed. This
volume also features discussions of current insights on Notch's
role for embryologic tissue patterning, for stem cells, in
senescence, and on the regulation of Notch signaling by epigenetic
and other factors including microRNAs, long non-codingRNAs, and
more. Taken as a whole, with its companion books - Notch Signaling
in Embryology and Notch Signaling in Cancer - this is a definitive
discussion of the topic, presented by internationally-recognized
contributors. Presented in a coherent and accessible structure,
this revised and updated second edition is an essential and
up-to-date guide for oncologists, embryologists, researchers and
advanced students.
This thoroughly revised second edition is an up-to-date overview of
the current knowledge of Notch and Notch signaling in embryology
and cancer. It discusses this topic from Notch's role in the
development of the embryo to the Notch signaling pathway's role in
the development of a number of cancers, including breast cancer,
malignant melanoma, Non-melanoma skin cancer, intestinal cancer and
others. In the years since the previous edition, there have been
numerous developments and insights within this rapidly moving
field, making this new edition urgently needed. This volume also
features discussions of current insights on Notch's role in
senescence, the regulation of Notch signaling by microRNAs, Notch's
role in the microbiome, diet and its influence on Notch signaling
and more. Taken as a whole, with its companion books - Molecular
Biology of Notch Signaling and Notch Signaling in Cancer - this is
a definitive discussion of the topic, presented by
internationally-recognized contributors. Presented in a coherent
and accessible structure, this revised and updated second edition
is an essential and up-to-date guide for oncologists,
embryologists, researchers and advanced students.
This thoroughly revised second edition is an up-to-date overview of
the current knowledge of Notch and Notch signaling in embryology
and cancer. It discusses this topic from Notch's role in the
development of the embryo to the Notch signaling pathway's role in
the development of a number of cancers, including breast cancer,
malignant melanoma, Non-melanoma skin cancer, intestinal cancer and
others. In the years since the previous edition, there have been
numerous developments and insights within this rapidly moving
field, making this new edition urgently needed. This volume also
features discussions of current insights on Notch's role in
senescence, the regulation of Notch signaling by microRNAs, Notch's
role in the microbiome, diet and its influence on Notch signaling
and more. Taken as a whole, with its companion books -- Notch
Signaling and Embryologic Development and Molecular Basis of Notch
Signaling - this is a definitive discussion of the topic, presented
by internationally-recognized contributors. Presented in a coherent
and accessible structure, this revised and updated second edition
is an essential and up-to-date guide for oncologists,
embryologists, researchers and advanced students.
This thoroughly revised second edition is an up-to-date overview of
the current knowledge of Notch and Notch signaling in embryology
and cancer. It summarizes the newest achievements on this topic
from Notch's flag-ship function in the development of the embryo
and for various inherited diseases to the Notch signaling pathway's
role in the development of leukemia and in a number of cancers,
including skin cancer, intestinal cancer and others. Additionally,
the emerging new role of the Notch signaling pathway as a promising
target for prevention and therapy of various diseases, including
cancer, is discussed. In the years since the previous edition,
there have been numerous developments and insights within this
rapidly moving field, making this new edition urgently needed. This
volume also features discussions of current insights on Notch's
role for embryologic tissue patterning, for stem cells, in
senescence, and on the regulation of Notch signaling by epigenetic
and other factors including microRNAs, long non-codingRNAs, and
more. Taken as a whole, with its companion books - Notch Signaling
in Embryology and Notch Signaling in Cancer - this is a definitive
discussion of the topic, presented by internationally-recognized
contributors. Presented in a coherent and accessible structure,
this revised and updated second edition is an essential and
up-to-date guide for oncologists, embryologists, researchers and
advanced students.
This thoroughly revised second edition is an up-to-date overview of
the current knowledge of Notch and Notch signaling in embryology
and cancer. It discusses this topic from Notch's role in the
development of the embryo to the Notch signaling pathway's role in
the development of a number of cancers, including breast cancer,
malignant melanoma, Non-melanoma skin cancer, intestinal cancer and
others. In the years since the previous edition, there have been
numerous developments and insights within this rapidly moving
field, making this new edition urgently needed. This volume also
features discussions of current insights on Notch's role in
senescence, the regulation of Notch signaling by microRNAs, Notch's
role in the microbiome, diet and its influence on Notch signaling
and more. Taken as a whole, with its companion books - Molecular
Biology of Notch Signaling and Notch Signaling in Cancer - this is
a definitive discussion of the topic, presented by
internationally-recognized contributors. Presented in a coherent
and accessible structure, this revised and updated second edition
is an essential and up-to-date guide for oncologists,
embryologists, researchers and advanced students.
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