This issue of Otolaryngologic Clinics, guest edited by Drs. Sarah K. Wise, Ashkan Monfared, and Nicole C. Schmitt is devoted to Biologics in Otolaryngology. This issue is one of six selected each year by our series consulting editor, Dr. Sujana S. Chandrasekhar. Articles in this issue include: Biologics in otolaryngology overview, Current evidence for biologic therapy in chronic rhinosinusitis with nasal polyposis, Choosing the right patient for biologic therapy in CRSwNP, Knowledge gaps and research needs for biologic therapy in rhinology practice, Mechanisms and practical use of biologic therapies for allergy and asthma indications, Immunotherapeutic strategies in head and neck cancer, Cetuximab in head and neck cancer, Anti-PD-1 immune checkpoint blockade for head and neck cancer, Advances in adoptive cell therapy for head and neck cancer, Biologics for the treatment of recurrent respiratory papillomatosis, Past and future biologics for otologic disorders, Biological treatments for Neurofibromatosis Type II and other skullbase disorders, and Biologics in treatment of autoimmune ear disorders.

The quintessential how-to guide on treating allergies for day-to-day practice While encyclopedic tomes on the treatment of allergies have a place on the library shelves of otolaryngologists, Handbook of Otolaryngic Allergy provides a user-friendly office resource clinicians can consult on a daily basis. Written by Christine Franzese, Cecelia Damask, Sarah Wise, and Matthew Ryan, the book encompasses the basic science of allergies, essential knowledge, and how to perform each procedure. Part one starts with basic immunology and allergic rhinitis definition and classifications, followed by discussion of sensitivities vs. clinical allergies, the unified airway concept, and different classes of inhalant allergens. Parts two and three detail all aspects of diagnosis and diverse skin testing methods such as Specific IgE testing. Subsequent parts discuss current treatment methods, allergy emergencies such as anaphylaxis, atopic disorders, and professional issues clinicians must tackle to successfully incorporate allergy treatment into practice. Key Highlights The use of diverse types of pharmacotherapy including decongestants, anti-cholinergics, and antihistamines, as well as biologics, alternative medicines, and monosensitization vs. polysensitization Discussion of immunotherapy approaches including subcutaneous, sublingual, sublingual tablets, and oral mucosal Managing associated atopic disorders such as penicillin allergy, asthma, food allergies, eosinophilic esophagitis, and atopic dermatitis Worksheets with correct answers enable self-testing and accurate vial mixing/preparation This user-friendly reference is a must-have companion for otorhinolaryngology residents and practitioners at any stage of their careers who treat patients with allergies. This book includes complimentary access to a digital copy on https://medone.thieme.com.

Office-Based Rhinology conveys the principles and techniques necessary for successfully undertaking various rhinology procedures in the office setting. The procedures described will range from those commonly performed in the physician's office (e.g. nasal endoscopy and debridement) to certain procedures often performed in the operating room for which, in certain patients, an office setting would be appropriate (e.g. nasal polypectomy and drainage of mucoceles). It also covers relevant sinonasal anatomy and radiology, proper patient selection, and appropriate room setup. Its straightforward approach makes it an easy to use reference, a must-have for practicing otolaryngologists and senior level residents. The book comes with a DVD which includes 28 surgical videos.