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This detailed volume aims to elucidate the molecular mechanisms
that underlie antifungal resistance. The book highlights methods to
identify and characterize antifungal activity, to define and
characterize strains with altered responses to antifungal drugs, to
investigate the genetic and molecular mechanisms of these
alterations of antifungal drug susceptibility, and, finally, to
approach the study of these processes in animal models of fungal
infection. Written for the highly successful Methods in Molecular
Biology series, chapters include introductions to their respective
topics, lists of the necessary materials and reagents, step-by-step
and readily reproducible laboratory protocols, as well as tips on
troubleshooting and avoiding known pitfalls. Authoritative
and practical, Antifungal Drug Resistance: Methods and Protocols
serves as an ideal resource for the field and a guide for
investigators to study this important translational aspect of
fungal biology.
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