In 1943, Jerald C. McIntire is supposed to die in a grenade explosion in the Ardennes forest in World War II. He miraculously survives, but from that point on Jerry no longer needs to eat or sleep, he has no emotions, and he never ages. After several suicide attempts, Jerry discovers he can't die. But how is this possible?

Nearly twenty years after his first brush with death, Jerry learns that he somehow broke the realm of the natural order. Even God Himself isn't sure how it happened, but Jerry is the only man ever born without a soul. The archangel Michael informs him that in the Soul War, good and evil are bound by certain laws and honor checks. Jerry, however, is bound by nothing and can therefore serve as the Master's Centurion-an agent of God bestowed with the name Jericho.

Jericho roams the streets of New York City, keeping order between the agents of Heaven and Hell, the angelus and the demonata. When a rogue deity, an ancient Hittite dragon god, comes to Earth and begins preying on both angels and demons, Jericho must step in to maintain the balance. But he stumbles into a much larger plot-one that threatens to irreparably damage the Balance of the Soul War and end all things.