Recognized scientists and clinicians from around the world discuss the most recent molecular approaches to understanding the cardiovascular system in both health and disease. The authors focus on all components of the system, including blood vessels, heart, kidneys, and the brain, and cover disease states ranging from vascular and cardiac dysfunction to stroke and hypertension. The methods described for identifying the genes that cause susceptibility to cardiovascular diseases emphasize the possibility of discovering new drug targets. Authoritative and ground-breaking, Cardiovascular Genomics offers an unprecedented examination of both the cutting-edge scientific approaches now possible and the results obtained from them in the new science of cardiovascular genomics.

An understanding of Hedgehog structures is an essential component in any chessplayer's knowledge. These structures arise when the black c-pawn is exchanged early on for the white d-pawn (as in the Sicilian Defence). White then adopts a formation with pawns on c4 and e4 and Black curls up in a Hedgehog formation with pawns on a6, b6, d6 and e6. ----- These structures are important as they can arise from an extraordinary variety of openings including the Sicilian Defence, the English Opening and the Queen's Indian Defence. Play is usually highly intricate with White hoping to exploit the natural space advantage while Black remains solid and looks to break out of his or her carapace with the classical thrusts ...b7-b5 and ...d7-d5. ----- Everything you need to know about the Hedgehog systems. --- The structure emphasizes plans and strategies. --- Written by an expert on the opening.