The early detection of acute blood loss is becoming more important for diagnostic purpose especially with the development of newer portable ultrasound device. Use of the ultrasound in the detection of acute blood loss via measuring the IVC diameter is not the standard clinical practice at the current moment. Current evidence suggests that acute blood loss can be detected early in hypovolemic patient by measuring the IVC diameter. The clinical implication of this study, IVCe was a great marker to determine the volume loss through bleeding in trauma patient. The measurement of the IVC diameter was also a reliable indicator of shock in trauma or medical hypovolemic cases and may even predict it in patients who have normal blood pressure due to sympathetic activity.