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Lectins (Hardcover)
Sharon Nathan, Lis Halina
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R2,391
Discovery Miles 23 910
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Ships in 18 - 22 working days
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Lectins are an important group of proteins, which bind to
carbohydrates and can agglutinate cells or precipitate
polysaccharides and glycoproteins. These agglutinating and
precipitating properties are very similar to those of antibodies,
and hence many of the methods used in lectin research are based on
immunochemical techniques. Lectins are however not of immune
origin, and are found in almost all organisms, including plants and
micro-organisms. Current interest in lectins derives particularly
from their usefulness in detecting and studying carbohydrates in
solution and on cell surfaces. Studies of lectin-carbohydrate
interactions are providing information on the precise molecular
details of the interactions between proteins and carbohydrates in
general. Lectins also serve as valuable tools in biological and
medical research, in areas as diverse as separation and
characterization of glycoproteins and glycopeptides, typing of
bacteria and fractionation of lymphocytes and of bone marrow cells.
Their biological role is uncertain but is generally believed to be
primarily as recognition determinants in mirco-organisms, plants
and animals. The purpose of the book is to give an accessible
overview of the properties of lectins, their possible roles and
their applications in biology and biomedical research in
biochemistry and cell biology. This book should be of interest to
biochemists, biologists, microbiologists, pathologists,
histologists, cancer researchers, immunologists and haematologists.
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