This collection features five peer-reviewed reviews on managing bacterial diseases of poultry. The first chapter provides a brief overview of Campylobacter in poultry production and the routes of transmission from bird to human. It considers current and future challenges in controlling Campylobacter, as well as the control measures implemented to reduce the occurrence of infection in poultry flocks. The second chapter discusses economically-important enteric diseases and disorders of poultry. The chapter highlights the aetiology of these diseases and explores more sustainable alternatives to promote gastrointestinal health, such as plant-derived extracts, organic acids, prebiotics and probiotics. The third chapter provides an overview of best practices to manage disease outbreaks in poultry. It reviews current disease preventative measures, health monitoring procedures, as well as disease investigation techniques. The fourth chapter reviews the emergence and re-emergence of several infectious pathogens in poultry production and the consequent need to improve current biosecurity measures in poultry flocks to ensure optimal animal health and welfare. The final chapter considers the main alternatives to antibiotics in preventing zoonoses and other major pathogens in poultry. The chapter reviews the sector's use of prebiotics and related compounds, as well as the beneficial effects of their use.