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This book systemically presents the latest research on lectins,
covering all the major topics in the field, including the
heterocomplex of lectins and Toll-like receptors, protective versus
pathogenic functions in connection with microbial infections, and
novel strategies for enhancing host immunity against infectious
diseases caused by viruses, bacteria, and fungi. Lectins are a
large group of glycan-binding proteins that recognize diverse
glycan and non-glycan structures expressed on prokaryotic and
eukaryotic cells, and are vital to cell-cell interactions, the
attachment of microbes to host cells, and the recognition and
activation of immune responses to exogenous and endogenous danger
signals. The composition and structure of microbes are complex and
include numerous 'pathogen-associated molecular patterns' or
'damage-associated molecular patterns'. As such, microbes'
interactions with immune cells activate multiple innate immunity
receptors and produce distinct inflammatory reactions, which can be
protective to contain microbial invasion, or pathogenic to cause
tissue damage and shock syndrome in the host. The book shares
lessons learned from state-of-the art research in this field,
highlights the latest discoveries, and provides insightful
discussions on lectin-mediated inflammatory reactions, while also
outlining future research directions.
This book systemically presents the latest research on lectins,
covering all the major topics in the field, including the
heterocomplex of lectins and Toll-like receptors, protective versus
pathogenic functions in connection with microbial infections, and
novel strategies for enhancing host immunity against infectious
diseases caused by viruses, bacteria, and fungi. Lectins are a
large group of glycan-binding proteins that recognize diverse
glycan and non-glycan structures expressed on prokaryotic and
eukaryotic cells, and are vital to cell-cell interactions, the
attachment of microbes to host cells, and the recognition and
activation of immune responses to exogenous and endogenous danger
signals. The composition and structure of microbes are complex and
include numerous 'pathogen-associated molecular patterns' or
'damage-associated molecular patterns'. As such, microbes'
interactions with immune cells activate multiple innate immunity
receptors and produce distinct inflammatory reactions, which can be
protective to contain microbial invasion, or pathogenic to cause
tissue damage and shock syndrome in the host. The book shares
lessons learned from state-of-the art research in this field,
highlights the latest discoveries, and provides insightful
discussions on lectin-mediated inflammatory reactions, while also
outlining future research directions.
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