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This book emphasizes the important role of invertebrates in
forensic sciences in the detection of crimes, determining the time
and place of death, estimating the minimum Post-Mortem Interval
(PMI), and determining the cause of death. The initial chapter
discusses the forensically essential invertebrates, especially
flies under Order Diptera. Further, the book highlights the
importance, biology, taxonomy, and biodiversity of flies under
Order Diptera with forensic importance. It also discusses the
Cuticular HydroCarbons (CHC) and spectrometry-based studies
reported from flies and larvae of forensic importance. It further
reviews the importance of DNA barcoding in molecular taxonomy-based
studies on forensic flies through understanding, identification,
and grouping the organisms. Towards the end, this book presents the
applications and limitations of forensic entomology in cases of
animal cruelty to a veterinary professional. ​
This book gives an overview of applications of
Machine Learning (ML) in diverse fields of biological
sciences, including healthcare, animal sciences, agriculture, and
plant sciences. Machine learning has major applications in
process modelling, computer vision, signal processing, speech
recognition, and language understanding and processing and life,
and health sciences. It is increasingly used in understanding DNA
patterns and in precision medicine. This book is divided into
eight major sections, each containing chapters that describe the
application of ML in a certain field. The book begins by giving an
introduction to ML and the various ML methods. It then covers
interesting and timely aspects such as applications in genetics,
cell biology, the study of plant-pathogen interactions, and animal
behavior. The book discusses computational methods for toxicity
prediction of environmental chemicals and drugs, which forms
a major domain of research in the field of
biology.  It is of relevance to post-graduate students
and researchers interested in exploring the interdisciplinary areas
of use of machine learning and deep learning in life sciences.
Stem cells hold great promise for cell therapy, tissue engineering,
regenerative medicine and pharmaceutical and biotechnological
applications. This book highlights the potency of stem cells, their
property of self-renewal and their ability to differentiate into
different cell lineages. It further describes the different markers
to identify stem cells, sources, methods of isolation, culture
including 2D, 3D and beyond and their cryopreservation. This is
among the first books to discuss glycosylation and sialylation in
stem cells. Chapters describe application of stem cells in
regenerative medicine and therapy, and highlight their application
in cancer therapy and spinal cord injury. The book talks about the
important patents on stem cells. The book also highlights the plant
stem cells, discussing their pluoripotent nature, role in organ
regeneration after injury, specific stem cell niches, that signals
to block differentiation studied in plants shoot, root, and
vascular meristems, differentiation of plant stem cell,
transcriptional regulation and epigenetic modification of plant
stem cells. This book is exciting and cutting edge. It will be of
great interest to doctors, students and researchers in the field of
regenerative medicine, cancer , biotechnology and plant sciences.
Applications of nanoparticles to the human life and tools in
diagnosis and therapy in field of clinical medicine holds
importance and has been an prime focus of biomedical and clinical
research for quite sometime, though their application in veterinary
medicine is a relatively new focus area of research. Prior to human
applications, studies are initially conducted on animals models.
Thus toxicity based studies and study of impact of nanoparticles on
animal immune system finds importance. In the second volume of the
book we discuss the immune system in animals across invertebrates
and vertebrate phylas and discuss the impact of nanoparticles in
animals life, health, survival and immune system. The book
highlights the toxic effects of nanoparticles as environmental
pollutants and their adverse impact on animal life forms. Both
volumes are also included in a set ISBN 978-3-11-065666-4.
The fast development in the field of nanotechnology has led to a
high variety of nanoparticles. Nanoparticles find importance in
every sphere of human lives and more so in the recent years have
tremendous applications in the sector of biomedical clinical
medicine as diagnostic, prognostic and imaging tools. Their risk to
human and animal life as well as to the environment is still
unclear. Therefore, the study of the impact of nanoparticles on
human and animal life is important. Volume I highlights the impact
of nanoparticles on the human immune system. While discussing the
basic biology of the immune system, this book highlights the
downstream effect of nanoparticles on the human immune system.
Research studies on the development of better and more effective
nanoparticles with more precise and accurate effects and with toxic
minimal side effects are discussed in the book. Both volumes are
also included in a set ISBN 978-3-11-065666-4.
Stem cells hold great promise for cell therapy, tissue engineering,
regenerative medicine and pharmaceutical and biotechnological
applications. This book highlights the potency of stem cells, their
property of self-renewal and their ability to differentiate into
different cell lineages. It further describes the different markers
to identify stem cells, sources, methods of isolation, culture
including 2D, 3D and beyond and their cryopreservation. This is
among the first books to discuss glycosylation and sialylation in
stem cells. Chapters describe application of stem cells in
regenerative medicine and therapy, and highlight their application
in cancer therapy and spinal cord injury. The book talks about the
important patents on stem cells. The book also highlights the plant
stem cells, discussing their pluoripotent nature, role in organ
regeneration after injury, specific stem cell niches, that signals
to block differentiation studied in plants shoot, root, and
vascular meristems, differentiation of plant stem cell,
transcriptional regulation and epigenetic modification of plant
stem cells. This book is exciting and cutting edge. It will be of
great interest to doctors, students and researchers in the field of
regenerative medicine, cancer , biotechnology and plant sciences.
The immune system is highly complex system with large number of
macromolecules, signaling pathways, protein-protein interactions,
and gene expressions. Studies from genomics, transcriptomics,
metabolomics are generating huge high throughput data that needs to
be analyzed for understanding the Immune system in Health and
Disease. Computational approaches arehelping in understanding the
study of complex biology of immunology and thereby enabling design
of therapeutic strategies in diseases like infectious diseases,
immunodeficiency, allergic, hypersensitive, autoimmune disorders
and diseases like Cancer, HIV etc. Computational Immunology: Basics
highlights the basics of the immune system and function in health
and disease. This book offers comprehensive coverage of the most
essential topics, including Overview of Immunology and
computational Immunology Immune organs and cells, antigen,
antibody, B, cell, T cell Antigen Processing and presentation
Diseases due to abnormalities of the immune system Cancer Biology
Shyamasree Ghosh (MSc, PhD, PGDHE, PGDBI), is currently working in
the School of Biological Sciences, National Institute of Science
Education and Research (NISER), Bhubaneswar, DAE, Govt of India,
graduated from the prestigious Presidency College Kolkata in 1998.
She was awarded the prestigious National Scholarship from the
Government of India. She has worked and published extensively in
glycobiology, sialic acids, immunology, stem cells and
nanotechnology. She has authored several publications that include
books and encyclopedia chapters in reputed journals and books.
Computational Immunology: Applications focuses on different
mathematical models, statistical tools, techniques, and
computational modelling that helps in understanding complex
phenomena of the immune system and its biological functions. The
book also focuses on the latest developments in computational
biology in designing of drugs, targets, biomarkers for early
detection and prognosis of a disease. It highlights the
applications of computational methods in deciphering the complex
processes of the immune system and its role in health and disease.
This book discusses the most essential topics, including Next
generation sequencing (NGS) and computational immunology
Computational modelling and biology of diseases Drug designing
Computation and identification of biomarkers Application in organ
transplantation Application in disease detection and therapy
Computational methods and applications in understanding of the
invertebrate immune system S Ghosh is MSc, PhD, PGDHE, PGDBI, is
PhD from IICB, CSIR, Kolkata, awarded the prestigious National
Scholarship from the Government of India. She has worked and
published extensively in glycobiology, sialic acids, immunology,
stem cells and nanotechnology. She has authored several
publications that include books and encyclopedia chapters in
reputed journals and books.
This book gives an overview of applications of Machine Learning
(ML) in diverse fields of biological sciences, including
healthcare, animal sciences, agriculture, and plant sciences.
Machine learning has major applications in process modelling,
computer vision, signal processing, speech recognition, and
language understanding and processing and life, and health
sciences. It is increasingly used in understanding DNA patterns and
in precision medicine. This book is divided into eight major
sections, each containing chapters that describe the application of
ML in a certain field. The book begins by giving an introduction to
ML and the various ML methods. It then covers interesting and
timely aspects such as applications in genetics, cell biology, the
study of plant-pathogen interactions, and animal behavior. The book
discusses computational methods for toxicity prediction of
environmental chemicals and drugs, which forms a major domain of
research in the field of biology. It is of relevance to
post-graduate students and researchers interested in exploring the
interdisciplinary areas of use of machine learning and deep
learning in life sciences.
This monograph summarizes the current knowledge on potential health
hazards induced by nanomaterials from different sources and sort
such as food, drugs and silver nanoparticles. Methods to assess
toxicity as well as known effects on the genome, neuronal and
respiratory system are discussed. Besides the impact on human and
animal life the books also addresses aquatic toxicity.
Sialic Acids and Sialoglycoconjugates in the Biology of Life,
Health and Disease enables the reader to understand the role of
sialylation as a post translational modification. The book provides
insights on the latest knowledge in the field of sialoglycobiology.
Sialic acids as terminal residues of oligosaccharide chains play
crucial roles in several cellular recognition events. Synthesized
post translationally, they play an important role in recognition,
signaling, immunological response and cell-cell interaction.
Improper sialylations have been associated with several diseases
including cancer. In the post genomics and proteomics era,
sialoglybiology has become more and more important in deciphering
health and disease conditions.
This book explores the latest developments in the field the acute
phase protein (APP), C-reactive protein or CRP in different
diseases, highlighting the structural and functional aspects of CRP
in disease biology. Divided into 5 sections, the book examines
important topics such as the role of CRP in neurodegenerative,
cardiac and parasitic diseases, as well as in cancer and
inflammatory bowel disease, and the expression of CRP in pediatric
respiratory diseases. In addition it discusses the clinical role of
CRP in diagnostics and therapeutics, sepsis, ICU and ITU patients,
and also as a primary marker for inflammation. Given its scope,
this book will appeal to scholars in various fields of medicine and
biology.
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