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Helicobacter pylori is one of the most common causes of chronic
infections in human. A close relationship is now thought to exist
between H. pylori and peptic ulcer disease, gastritis, and certain
other gastroduodenal diseases. Also, it is now firmly established
that infection with H. pylori is a key etiological factor in peptic
ulcer disease, gastric mucosa-associated lymphoid tissue lymphoma,
and gastric adenocarcinoma. Furthermore, several studies have shown
that eradication of H. pylori plays an important role in the
treatment of some gastric-intestinal diseases. Biopsy specimens
were collected from 150 dyspeptic patients. One hundred and seven
were positive for H. pylori. Susceptibilities were determined for
these isolates by disc diffusion methods. The prevalence of
positive H. pylori isolates among the dyspeptic patients was
71.33%. The resistance rate to metronidazole, tetracycline,
clarithromycin, and amoxicillin was 86%, 7.4%, 5.6%, and 0.9%,
respectively. Metronidazole resistance was a character of H. pylori
isolates within most patients in Ismailia, while amoxicillin
resistance is rare.
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