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This work provides a review of biological networks as a model for
analysis, presenting and discussing a number of illuminating
analyses. Biological networks are an effective model for providing
insights about biological mechanisms. Networks with different
characteristics are employed for representing different scenarios.
This powerful model allows analysts to perform many kinds of
analyses which can be mined to provide interesting information
about underlying biological behaviors. The text also covers
techniques for discovering exceptional patterns, such as a pattern
accounting for local similarities and also collaborative effects
involving interactions between multiple actors (for example genes).
Among these exceptional patterns, of particular interest are
discriminative patterns, namely those which are able to
discriminate between two input populations (for example
healthy/unhealthy samples). In addition, the work includes a
discussion on the most recent proposal on discovering
discriminative patterns, in which there is a labeled network for
each sample, resulting in a database of networks representing a
sample set. This enables the analyst to achieve a much finer
analysis than with traditional techniques, which are only able to
consider an aggregated network of each population.
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