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First isolated as a chemical compound by a Russian chemist in 1866,
dimethyl sulfoxide (DMSO) proved to be a near-perfect solvent for
decades before its remarkable biological and medical activities
were discovered. DMSO is one of the most prodigious agents ever to
come out of the world of drug development. Its wide range of
biological actions involving plants, animals, and humans has led to
the publication of tens of thousands of articles in the scientific
literature. Dimethyl Sulfoxide (DMSO) in Trauma and Disease
examines the major clinical uses of DMSO in humans as supported by
basic evidence derived from experiments in animals, including its
effects in disorders such as osteoarthritis, interstitial cystitis,
gastrointestinal inflammatory changes, scleroderma, respiratory
distress, myasthenia gravis, cardiac disease, traumatic brain
injury, and Alzheimer's disease. The effects of DMSO on pain,
cancer, stroke, and spinal cord injury are also discussed. The book
explores how its chemical structure is able to react and deactivate
toxic molecules generated by DNA damage, free radical formation,
inflammation, oxidation, and infection. For the first time, the
collective data on the biological, chemical, and medical actions of
DMSO are presented and analyzed from the published scientific
literature. Clearly written, the book incorporates
easy-to-understand scientific descriptions that appeal both to
health care professionals and the millions of people worldwide who
have used DMSO for an assortment of ailments as a prescriptive or
off-label medication.
First isolated as a chemical compound by a Russian chemist in 1866,
dimethyl sulfoxide (DMSO) proved to be a near-perfect solvent for
decades before its remarkable biological and medical activities
were discovered. DMSO is one of the most prodigious agents ever to
come out of the world of drug development. Its wide range of
biological actions involving plants, animals, and humans has led to
the publication of tens of thousands of articles in the scientific
literature. Dimethyl Sulfoxide (DMSO) in Trauma and Disease
examines the major clinical uses of DMSO in humans as supported by
basic evidence derived from experiments in animals, including its
effects in disorders such as osteoarthritis, interstitial cystitis,
gastrointestinal inflammatory changes, scleroderma, respiratory
distress, myasthenia gravis, cardiac disease, traumatic brain
injury, and Alzheimer's disease. The effects of DMSO on pain,
cancer, stroke, and spinal cord injury are also discussed. The book
explores how its chemical structure is able to react and deactivate
toxic molecules generated by DNA damage, free radical formation,
inflammation, oxidation, and infection. For the first time, the
collective data on the biological, chemical, and medical actions of
DMSO are presented and analyzed from the published scientific
literature. Clearly written, the book incorporates
easy-to-understand scientific descriptions that appeal both to
health care professionals and the millions of people worldwide who
have used DMSO for an assortment of ailments as a prescriptive or
off-label medication.
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