Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.

How was the history of post-classical Rome and of the Church written in the Catholic Reformation? Historical texts composed in Rome at this time have been considered secondary to the city's significance for the history of art. The Invention of Papal History corrects this distorting emphasis and shows how historical writing became part of a comprehensive formation of the image and self-perception of the papacy. By presenting and fully contextualising the path-breaking works of the Augustinian historian Onofrio Panvinio (1530-1568), Stefan Bauer shows what type of historical research was possible in the late Renaissance and the Catholic Reformation. Crucial questions were, for example: How were the pontiffs elected? How many popes had been puppets of emperors? Could any of the past machinations, schisms, and disorder in the history of the Church be admitted to the reading public? Historiography in this period by no means consisted entirely of commissioned works written for patrons; rather, a creative interplay existed between, on the one hand, the endeavours of authors to explore the past and, on the other hand, the constraints of ideology and censorship placed on them. The Invention of Papal History sheds new light on the changing priorities, mentalities, and cultural standards that flourished in the transition from the Renaissance to the Catholic Reformation.

How was the history of post-classical Rome and of the Church written in the Catholic Reformation? Historical texts composed in Rome at this time have been considered secondary to the city's significance for the history of art. The Invention of Papal History corrects this distorting emphasis and shows how historical writing became part of a comprehensive formation of the image and self-perception of the papacy. By presenting and fully contextualising the path-breaking works of the Augustinian historian Onofrio Panvinio (1530-1568), Stefan Bauer shows what type of historical research was possible in the late Renaissance and the Catholic Reformation. Crucial questions were, for example: How were the pontiffs elected? How many popes had been puppets of emperors? Could any of the past machinations, schisms, and disorder in the history of the Church be admitted to the reading public? Historiography in this period by no means consisted entirely of commissioned works written for patrons; rather, a creative interplay existed between, on the one hand, the endeavours of authors to explore the past and, on the other hand, the constraints of ideology and censorship placed on them. The Invention of Papal History sheds new light on the changing priorities, mentalities, and cultural standards that flourished in the transition from the Renaissance to the Catholic Reformation.

Nach einem Herzeingriff - einer Operation oder dem Aufdehnen der Herzkranzgefasse - stellen sich viele Fragen:

- Was liegt meiner Herzerkrankung zugrunde?

- Wie kann ich behandelt werden? Welche Komplikationen kann es geben?

- Wie verhalte ich mich in der ersten Zeit nach der Operation?

- Wie gestalte ich meinen Alltag nach der Operation? Was darf ich, wo muss ich vorsichtig sein?

- Wie lebe ich, um meine Gesundheit zu erhalten?

Zuverlassige und detaillierte Antworten geben Ihnen drei erfahrene Herzchirurgen des Herzzentrums Lahr in diesem Buch.

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