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Gene expression studies have revealed diagnostic profiles and
upregulation of specific pathways in many solid tumors. The
explosion of new information in gene expression profiling could
potentially lead to the development of tailored treatments in many
solid tumors. In addition many studies are ongoing to validate
these signatures also in predicting response to hormonal,
chemotherapeutic and targeted agents in breast cancer as well as in
other tumors. Diagnostic, Prognostic and Therapeutic Value of Gene
Signatures provides readers a useful and comprehensive resource
about the range of applications of microarray technology in
oncological diseases. Topics covered include gene signatures and
soft tissue sarcomas, prognostic relevance of breast cancer
signatures, gene expression profiling of colorectal cancer and
liver metastasis, gene signatures in GISTs, CNVs and gene
expression profiles in pancreatic cancer, and gene signatures in
head/neck, lung and gastric tumors. Diagnostic, Prognostic and
Therapeutic Value of Gene Signatures will be of great value to
residents and fellows, physicians, pathologists and medical
oncologists.
Gene expression studies have revealed diagnostic profiles and
upregulation of specific pathways in many solid tumors. The
explosion of new information in gene expression profiling could
potentially lead to the development of tailored treatments in many
solid tumors. In addition many studies are ongoing to validate
these signatures also in predicting response to hormonal,
chemotherapeutic and targeted agents in breast cancer as well as in
other tumors. Diagnostic, Prognostic and Therapeutic Value of Gene
Signatures provides readers a useful and comprehensive resource
about the range of applications of microarray technology in
oncological diseases. Topics covered include gene signatures and
soft tissue sarcomas, prognostic relevance of breast cancer
signatures, gene expression profiling of colorectal cancer and
liver metastasis, gene signatures in GISTs, CNVs and gene
expression profiles in pancreatic cancer, and gene signatures in
head/neck, lung and gastric tumors. Diagnostic, Prognostic and
Therapeutic Value of Gene Signatures will be of great value to
residents and fellows, physicians, pathologists and medical
oncologists.
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