Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Stimulated by the increasing importance of chiral molecules as pharmaceuticals and the need for enantiomerically pure drugs, techniques in chiral chemistry have been expanded and refined, especially in the areas of chromatography, asymmetric synthesis, and spectroscopic methods for chiral molecule structural characterization. In addition to synthetic chiral molecules, naturally occurring molecules, which are invariably chiral and generally enantiomerically enriched, are of potential interest as leads for new drugs. VCD Spectroscopy for Organic Chemists discusses the applications of vibrational circular dichroism (VCD) spectroscopy to the structural characterization of chiral organic molecules. The book provides all of the information about VCD spectroscopy that an organic chemist needs in order to make use of the technique. The authors, experts responsible for much of the existing literature in this field, discuss the experimental measurement of VCD and the theoretical prediction of VCD. In addition, they evaluate the advantages and limitations of the technique in determining molecular structure. Given the availability of commercial VCD instrumentation and quantum chemistry software, it became possible in the late 1990s for chemists to use VCD in elucidating the stereochemistries of chiral organic molecules. This book helps organic chemists become more aware of the utility of VCD spectroscopy and provides them with sufficient knowledge to incorporate the technique into their own research.

Stimulated by the increasing importance of chiral molecules as pharmaceuticals and the need for enantiomerically pure drugs, techniques in chiral chemistry have been expanded and refined, especially in the areas of chromatography, asymmetric synthesis, and spectroscopic methods for chiral molecule structural characterization. In addition to synthetic chiral molecules, naturally occurring molecules, which are invariably chiral and generally enantiomerically enriched, are of potential interest as leads for new drugs.

VCD Spectroscopy for Organic Chemists discusses the applications of vibrational circular dichroism (VCD) spectroscopy to the structural characterization of chiral organic molecules. The book provides all of the information about VCD spectroscopy that an organic chemist needs in order to make use of the technique. The authors, experts responsible for much of the existing literature in this field, discuss the experimental measurement of VCD and the theoretical prediction of VCD. In addition, they evaluate the advantages and limitations of the technique in determining molecular structure.

Given the availability of commercial VCD instrumentation and quantum chemistry software, it became possible in the late 1990s for chemists to use VCD in elucidating the stereochemistries of chiral organic molecules. This book helps organic chemists become more aware of the utility of VCD spectroscopy and provides them with sufficient knowledge to incorporate the technique into their own research.

Polycystic ovary syndrome (PCOS) is the most common endocrine disturbance, affecting 10 15% of women in the UK. The definition of PCOS has been much debated, while its pathophysiology appears to be multifactorial and is still being actively researched. There is no doubt that PCOS has a significant effect on quality of life and psychological morbidity and, as many specialists are involved in its management, a multidisciplinary approach is required. The 59th RCOG Study Group brought together a range of experts who treat women with PCOS. This book presents the findings of the Study Group, including: a definition of PCOS the accuracy of diagnostic interventions the particular challenges of adolescent diagnosis and management the correlation to ethnicity current approaches to therapy the potential individualisation of therapy the role of the alternative therapies used to manage some aspects of PCOS."

This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.

"How you spend your resources really does speak to the ethics, morals, and values about what is important. I use these ideas each day to help schools leverage their resources in strategic and creative ways to meet students' needs." -Mary Nash, Assistant Superintendent Boston Public Schools, MA "A powerful new lens for looking at school resources by fundamentally changing the question from 'How much money do schools need to succeed?' to 'How well are resources being used to ensure student success?'" -Richard Murnane, Economist and Professor Harvard Graduate School of Education Strategically reorganize school resources to support instructional and performance priorities! How can schools best use the resources they already have? That question is at the heart of this inspiring book for school and district administrators challenged with increasing student performance without additional funding. Exploring the link between purposeful resource allocation and academic achievement, Karen Hawley Miles and Stephen Frank demonstrate how educational leaders can develop successful and strategic schools by assessing how well they use all available resources-people, time, and money-and by creating effective alternatives to meet goals. The authors use their extensive research with urban schools and districts to present case studies of schools that successfully reorganized resources to implement the "Big 3 Guiding Resource Strategies": improving teaching quality, creating individual attention, and maximizing academic time. The Strategic School offers planning guides, checklists, worksheets, and strategies aligned with ISLLC standards to help leaders: Assess current resource use in new ways that go beyond the typical budget review Organize resources more creatively and flexibly Craft a master schedule that works Connect resource allocation to student and school performance

Clitics are grammatical elements that are treated as independent words in syntax but form a phonological unit with the word that precedes or follows it. This volume brings together the facts about clitics in the Slavic languages, where they have become a focal points of recent research. The authors draw relevant generalizations across the Slavic languages and highlight the importance of these phenomena for linguistic theory.

Focusing on issues of case theory and comparative grammar, this study treats selected problems in the syntax of the Slavic languages from the perspective of Government-Binding theory. Steven Franks seeks to develop parametric solutions to related constructions among the various Slavic languages. A model of case based loosely on Jakobson's feature system is adapted to a variety of comparative problems in Slavic, including across-the-board constructions, quantification, secondary predication, null subject phenomena, and voice. Solutions considered make use of recent approaches to phrase structure, including the VP-internal subject hypothesis and the DP hypothesis. The book will serve admirably as an introduction to GB theory for Slavic linguists as well as to the range of problems posed by Slavic for general syntacticians.