For one-semester undergraduate or master's level introductory courses in Biostatistics.

This concise, algebra-based text is a straight forward, clear approach to biostatistics, containing rigorous explanations of elementary methods without the “bells and whistles” associated with other books that cover this topic. Its goal is to provide a sophisticated introduction of how statistics works at a beginning level. Every concept is carefully and clearly explained, enriched by a mathematical/statistical justification, and then illustrated by at least one concrete, worked data example. Beginning with basic concepts, the text allows readers to acquire the ability to understand rather complicated statistical issues, such as linear regression theory and application.

This practical guide to survival data and its analysis for readers with a minimal background in statistics shows why the analytic methods work and how to effectively analyze and interpret epidemiologic and medical survival data with the help of modern computer systems. The introduction presents a review of a variety of statistical methods that are not only key elements of survival analysis but are also central to statistical analysis in general. Techniques such as statistical tests, transformations, confidence intervals, and analytic modeling are presented in the context of survival data but are, in fact, statistical tools that apply to understanding the analysis of many kinds of data. Similarly, discussions of such statistical concepts as bias, confounding, independence, and interaction are presented in the context of survival analysis and also are basic components of a broad range of applications. These topics make up essentially a 'second-year', one-semester biostatistics course in survival analysis concepts and techniques for non-statisticians.

The vast majority of statistics books delineate techniques used to analyze collected data. The Joy of Statistics is not one of these books. It consists of a series of 42 "short stories", each illustrating how statistical methods applied to data produce insight and solutions to the questions the data were collected to answer. Real-life and sometimes artificial data are used to demonstrate the often painless method and magic of statistics. In addition, the text contains brief histories of the evolution of statistical methods and a number of brief biographies of the most famous statisticians of the 20th century. Sprinkled throughout are statistical jokes, puzzles and traditional stories. The levels of statistical texts span a spectrum, from elementary to introductory to application to theoretical to advanced mathematical. This book explores a variety of statistical applications using graphs and plots, along with detailed and intuitive descriptions, and occasionally a bit of 10th grade mathematics. Examples of a few of the topics included among these "short stories" are pet ownership, gambling games such as roulette, blackjack and lotteries, as well as more serious subjects such as comparison of black/white infant mortality risk, infant birth weight and maternal age, estimation of coronary heart disease risk and racial differences in Hodgkin disease. The statistical descriptions of these topics are in many cases accompanied by easy to understand explanations labelled "How it Works."

Analytic procedures suitable for the study of human disease are scattered throughout the statistical and epidemiologic literature. Explanations of their properties are frequently presented in mathematical and theoretical language. This well-established text gives readers a clear understanding of the statistical methods that are widely used in epidemiologic research without depending on advanced mathematical or statistical theory. By applying these methods to actual data, Selvin reveals the strengths and weaknesses of each analytic approach. He combines techniques from the fields of statistics, biostatistics, demography and epidemiology to present a comprehensive overview that does not require computational details of the statistical techniques described.
For the Third Edition, Selvin took out some old material (e.g. the section on rarely used cross-over designs) and added new material (e.g. sections on frequently used contingency table analysis). Throughout the text he enriched existing discussions with new elements, including the analysis of multi-level categorical data and simple, intuitive arguments that exponential survival times cause the hazard function to be constant. He added a dozen new applied examples to illustrate such topics as the pitfalls of proportional mortality data, the analysis of matched pair categorical data, and the age-adjustment of mortality rates based on statistical models. The most important new feature is a chapter on Poisson regression analysis. This essential statistical tool permits the multivariable analysis of rates, probabilities and counts.

This practical guide to survival data and its analysis for readers with a minimal background in statistics shows why the analytic methods work and how to effectively analyze and interpret epidemiologic and medical survival data with the help of modern computer systems. The introduction presents a review of a variety of statistical methods that are not only key elements of survival analysis but are also central to statistical analysis in general. Techniques such as statistical tests, transformations, confidence intervals, and analytic modeling are presented in the context of survival data but are, in fact, statistical tools that apply to understanding the analysis of many kinds of data. Similarly, discussions of such statistical concepts as bias, confounding, independence, and interaction are presented in the context of survival analysis and also are basic components of a broad range of applications. These topics make up essentially a 'second-year', one-semester biostatistics course in survival analysis concepts and techniques for non-statisticians.

Using real data from published sources, this engaging and lucid casebook shows how statistical tools can be used to analyze important epidemiologic issues. Its 18 cases are described succinctly and the wide variety of methods used to analyze them are then discussed in detail. The author's focus on describing, interpreting and presenting results will set this book apart from other texts.

Statistical analysis typically involves applying theoretically generated techniques to the description and interpretation of collected data. In this text, theory, application and interpretation are combined to present the entire biostatistical process for a series of elementary and intermediate analytic methods. The theoretical basis for each method is discussed with a minimum of mathematics and is applied to a research data example using a computer system called S-PLUS. This system produces concrete numerical results and increases one's understanding of the fundamental concepts and methodology of statistical analysis. This text is not a computer manual, even though it makes extensive use of computer language to describe and illustrate applied statistical techniques. This makes the details of the statistical process readily accessible, providing insight into how and why a statistical method identifies the properties of sampled data. The first chapter gives a simple overview of the S-PLUS language. The subsequent chapters use this valuable statistical tool to present a variety of analytic approaches. Combining statistical logic, data and computer tools, the author explores such topics as random number generation, general linear models, estimation, analysis of tabular data, analysis of variance and survival analysis. The end result is a clear and complete explanation of the way statistical methods can help one gain an understanding of collected data. Modern Applied Biostatistical Methods is unlike other statistical texts, which usually deal either with theory or with applications. It integrates the two elements into a single presentation of theoretical background, data, interpretation, graphics, and implementation. This all-around approach will be particularly helpful to students in various biostatistics and advanced epidemiology courses, and will interest all researchers involved in biomedical data analysis.