Written in the same accessible manner as previous editions, the fifth edition of Karch's Pathology of Drug Abuse is an essential guide to the pathology, toxicology, and pharmacology of commonly abused drugs. The book focuses on the investigation of drug-related deaths, practical approaches to the detection of drug abuse, and discussions of medical complications associated with each of the abused drugs. The Fifth Edition Now Features: Completely revised with hundreds of pages of wholly new coverage Extensive discussion of new synthetic cannabinoids and cathinone derivatives Expanded coverage of the functional and molecular pharmacology of cocaine and myocardial remodeling Expanded discussion of deaths related to prescription medications Detailed suggestions on the interpretation of postmortem drug measurements Many new high resolution full-color photomicrographs Additional, helpful new appendices on standard reference values Separate chapters are devoted to cocaine, naturally occurring stimulants, synthetic stimulants, hallucinogens, narcotics, anabolic steroids, disassociative anesthetics, solvent abuse, and marijuana. The book also offers detailed information on the origins, history, and production techniques used to make many of these drugs. Updated, revised, and newly illustrated, Karch's Pathology of Drug Abuse, Fifth Edition is a must-have reference for research and practice related to drug abuse. Steven B. Karch also discusses the book in a video on the CRC Press YouTube channel.

Written in the same accessible manner as previous editions, the fifth edition of Karch's Pathology of Drug Abuse is an essential guide to the pathology, toxicology, and pharmacology of commonly abused drugs. The book focuses on the investigation of drug-related deaths, practical approaches to the detection of drug abuse, and discussions of medical complications associated with each of the abused drugs. The Fifth Edition Now Features: Completely revised with hundreds of pages of wholly new coverage Extensive discussion of new synthetic cannabinoids and cathinone derivatives Expanded coverage of the functional and molecular pharmacology of cocaine and myocardial remodeling Expanded discussion of deaths related to prescription medications Detailed suggestions on the interpretation of postmortem drug measurements Many new high resolution full-color photomicrographs Additional, helpful new appendices on standard reference values Separate chapters are devoted to cocaine, naturally occurring stimulants, synthetic stimulants, hallucinogens, narcotics, anabolic steroids, disassociative anesthetics, solvent abuse, and marijuana. The book also offers detailed information on the origins, history, and production techniques used to make many of these drugs. Updated, revised, and newly illustrated, Karch's Pathology of Drug Abuse, Fifth Edition is a must-have reference for research and practice related to drug abuse. Steven B. Karch also discusses the book in a video on the CRC Press YouTube channel.

A Brief History of Cocaine, Second Edition provides a fascinating historical insight into the reasons why cocaine use is increasing in popularity and why the rise of the cocaine trade is tightly linked with the rise of terrorism The author illustrates the challenges faced by today's governments and explains why current anti-drug efforts have had only a limited effect on this global market. This updated edition reexamines the impact of cocaine production, trade, and consumption on society beginning in the 16th century. It shows how the commercialization of cocaine was driven by cartels of Swiss and German pharmaceutical companies and private enterprises across Europe, Asia, and the United States. The author shows how government policies slowly transformed from trade, shipping, and manufacturing regulations, with little or no success in stemming the flow of drugs. The book describes how anti-drug laws, treaties, and costly initiatives involving crop substitution, crop suppression, interdiction, and international cooperation were first attempted more than 400 years ago and why these strategies failed for Colonial Spain and later backfired on the League of Nations. The author shows how economic necessity among growers, the environmental impact of pesticides, the potential for genetic engineering of coca plants, and other loopholes have actually been counterproductive, undermining the current efforts to curb the cocaine trade. Featuring new and reorganized chapters, A Brief History of Cocaine, Second Edition contains the latest data and statistics relating drug trafficking to terrorism, and explains recent trends in worldwide production, consumption, cost competition, and international transport. This book offers a well-rounded historical perspective that is ideal for criminal justice practitioners, teachers, students, and anyone interested in this topic.

A Brief History of Cocaine, Second Edition provides a fascinating historical insight into the reasons why cocaine use is increasing in popularity and why the rise of the cocaine trade is tightly linked with the rise of terrorism The author illustrates the challenges faced by today's governments and explains why current anti-drug efforts have had only a limited effect on this global market. This updated edition reexamines the impact of cocaine production, trade, and consumption on society beginning in the 16th century. It shows how the commercialization of cocaine was driven by cartels of Swiss and German pharmaceutical companies and private enterprises across Europe, Asia, and the United States. The author shows how government policies slowly transformed from trade, shipping, and manufacturing regulations, with little or no success in stemming the flow of drugs. The book describes how anti-drug laws, treaties, and costly initiatives involving crop substitution, crop suppression, interdiction, and international cooperation were first attempted more than 400 years ago and why these strategies failed for Colonial Spain and later backfired on the League of Nations. The author shows how economic necessity among growers, the environmental impact of pesticides, the potential for genetic engineering of coca plants, and other loopholes have actually been counterproductive, undermining the current efforts to curb the cocaine trade. Featuring new and reorganized chapters, A Brief History of Cocaine, Second Edition contains the latest data and statistics relating drug trafficking to terrorism, and explains recent trends in worldwide production, consumption, cost competition, and international transport. This book offers a well-rounded historical perspective that is ideal for criminal justice practitioners, teachers, students, and anyone interested in this topic.