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Systemic autoimmune diseases can affect both the central and
peripheral nervous systems in a myriad of ways and through a
heterogeneous number of mechanisms leading to many different
clinical manifestations. As a result, neurological complications of
these disorders can result in significant morbidity and mortality.
Advances in the diagnosis, laboratory investigations, and
management of these conditions has placed an increasing burden on
the practicing clinician to correctly assess and treat these
patients.
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